Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Natalie Stickle"'
Autor:
Maria Kondratyev, Aleksandra Pesic, Troy Ketela, Natalie Stickle, Christine Beswick, Zvi Shalev, Stefano Marastoni, Soroush Samadian, Anna Dvorkin-Gheva, Azin Sayad, Mikhail Bashkurov, Pedro Boasquevisque, Alessandro Datti, Trevor J. Pugh, Carl Virtanen, Jason Moffat, Reidar A. Grénman, Marianne Koritzinsky, Bradly G. Wouters
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract During cancer development, tumor cells acquire changes that enable them to invade surrounding tissues and seed metastasis at distant sites. These changes contribute to the aggressiveness of metastatic cancer and interfere with success of the
Externí odkaz:
https://doaj.org/article/886fde5b19b44a0c8e8d3f024a37afbb
Autor:
Melanie Care, Jeanna McCuaig, Blaise Clarke, Sylvie Grenier, Raymond H Kim, Marjan Rouzbahman, Natalie Stickle, Marcus Q Bernardini, Tracy L. Stockley
Publikováno v:
Molecular Oncology, Vol 15, Iss 1, Pp 80-90 (2021)
The aim of this study was to determine the prevalence of somatic and germline pathogenic variants (PVs) in high‐grade serous cancer (HGSC) and to demonstrate the technical feasibility and effectiveness of a large‐scale, population‐based tumor t
Externí odkaz:
https://doaj.org/article/cd104b9b725b418b9089d7cf78c664d6
Autor:
Tracy Murphy, Stanley W.K. Ng, Ian King, Tong Zhang, Andrea Arruda, Jaime Claudio, Kristele Pan, Chantal Rockwell, Zhibin Lu, Natalie Stickle, Carl Virtanen, Vikas Gupta, Dawn Maze, Caroline McNamara, Aaron D. Schimmer, Andre C. Schuh, Hassan Sibai, Karen Yee, Dina Khalaf, Brian Leber, Mitchell Sabloff, Anne Tierens, Mark D. Minden, Tracy L. Stockley, Steven Chan, Jean C.Y. Wang
Publikováno v:
Blood. 140:9122-9124
Autor:
Liat Hogen, Emily Van De Laar, Marjan Rouzbaham, Marcus Bernardini, Alicia Tone, Stephenie Prokopec, Jeffrey Bruce, Natalie Stickle, Trevor Pugh
Publikováno v:
E-Posters.
Autor:
Augustin Toma, Claudia dos Santos, Beata Burzyńska, Monika Góra, Marek Kiliszek, Natalie Stickle, Holger Kirsten, Leah B. Kosyakovsky, Bo Wang, Sean van Diepen, Slava Epelman, Yishay Szekely, John C. Marshall, Filio Billia, Patrick R. Lawler
Publikováno v:
Circulation research. 131(1)
Autor:
Jeanna M. McCuaig, Natalie Stickle, Tracy Stockley, Talin Boghosian, Tong Zhang, Raymond H. Kim, Alexandra Volenik, Rochelle Demsky, Nicole Ricker, Alicia A. Tone, Terri Stuart-McEwan, Patricia Shaw, Sarah E. Ferguson, Taymaa May, Suzanne Kamel-Reid, Carl Virtanen, Amit M. Oza, Marcus Q. Bernardini, Susan Armel, Stephane Laframboise, Tina Romagnuolo
Publikováno v:
Obstetrical & Gynecological Survey. 76:476-478
Up to 20% of high-grade serous ovarian carcinomas (HGSOC) are hereditary; however, historical uptake of genetic testing is low. We used a unique combination of approaches to identify women in Ontario, Canada, with a first-degree relative (FDR) who di
Autor:
Tracy Stockley, Melanie Care, Marcus Q. Bernardini, Natalie Stickle, Marjan Rouzbahman, Blaise A. Clarke, Raymond H. Kim, Sylvie Grenier, Jeanna McCuaig
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 15, Iss 1, Pp 80-90 (2021)
Molecular Oncology, Vol 15, Iss 1, Pp 80-90 (2021)
The presence of somatic or germline BRCA1/2 pathogenic variants impacts the effectiveness of PARP inhibitor therapy in high‐grade serous ovarian cancer. This study demonstrates that a large‐scale tumor testing program can effectively and accurate
Autor:
Stanley W. K. Ng, Tracy Murphy, Ian King, Tong Zhang, Michelle Mah, Zhibin Lu, Natalie Stickle, Narmin Ibrahimova, Andrea Arruda, Amanda Mitchell, Ming Mai, Rong He, Bindu Swapna Madala, David S. Viswanatha, John E. Dick, Steven Chan, Carl Virtanen, Mark D. Minden, Timothy Mercer, Tracy Stockley, Jean C. Y. Wang
Publikováno v:
Blood advances. 6(3)
Leukemia stem cells (LSCs) are linked to relapse in acute myeloid leukemia (AML). The LSC17 gene expression score robustly captures LSC stemness properties in AML and can be used to predict survival outcomes and response to therapy, enabling risk-ada
Autor:
Mahadeo A. Sukhai, Steven Van Vooren, Natalie Stickle, Mariam Thomas, Tong Zhang, Suzanne Kamel-Reid, Maksym Misyura, Gert Thijs, Tracy Stockley, Carl Virtanen, Swati Garg, Tina Smets, Philippe L. Bedard, Lillian L. Siu
Publikováno v:
The Journal of Molecular Diagnostics. 21:261-273
A common approach in clinical diagnostic laboratories to variant assessment from tumor molecular profiling is sequencing of genomic DNA extracted from both tumor (somatic) and normal (germline) tissue, with subsequent variant comparison to identify t
Autor:
Bryan Lo, Elizabeth McCready, Bekim Sadikovic, Tara Spence, Philippe L. Bedard, Celeste Yu, L.L. Siu, Tracy Stockley, Natalie Stickle, Helen Chow, Harriet Feilotter
Publikováno v:
Current Oncology
Volume 26
Issue 6
Pages 5379-732
Paediatrics Publications
Volume 26
Issue 6
Pages 5379-732
Paediatrics Publications
Background: A pilot inter-laboratory proficiency scheme for 5 Ontario clinical laboratories testing tumour samples for the Ontario-wide Cancer Targeted Nucleic Acid Evaluation (OCTANE) study was undertaken to assess proficiency in the identification