Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Natalie Silliman"'
Autor:
Austin K Mattox, Christopher Douville, Natalie Silliman, Janine Ptak, Lisa Dobbyn, Joy Schaefer, Maria Popoli, Cherie Blair, Kathy Judge, Kai Pollard, Christine Pratilas, Jaishri Blakeley, Fausto Rodriguez, Nickolas Papadopoulos, Allan Belzberg, Chetan Bettegowda
Publikováno v:
eLife, Vol 11 (2022)
Malignant peripheral nerve sheath tumors (MPNST) are the deadliest cancer that arises in individuals diagnosed with neurofibromatosis and account for nearly 5% of the 15,000 soft tissue sarcomas diagnosed in the United States each year. Comprised of
Externí odkaz:
https://doaj.org/article/5f4eeb9527be4d2ea6e9da2d44488190
Autor:
Simeon U Springer, Chung-Hsin Chen, Maria Del Carmen Rodriguez Pena, Lu Li, Christopher Douville, Yuxuan Wang, Joshua David Cohen, Diana Taheri, Natalie Silliman, Joy Schaefer, Janine Ptak, Lisa Dobbyn, Maria Papoli, Isaac Kinde, Bahman Afsari, Aline C Tregnago, Stephania M Bezerra, Christopher VandenBussche, Kazutoshi Fujita, Dilek Ertoy, Isabela W Cunha, Lijia Yu, Trinity J Bivalacqua, Arthur P Grollman, Luis A Diaz, Rachel Karchin, Ludmila Danilova, Chao-Yuan Huang, Chia-Tung Shun, Robert J Turesky, Byeong Hwa Yun, Thomas A Rosenquist, Yeong-Shiau Pu, Ralph H Hruban, Cristian Tomasetti, Nickolas Papadopoulos, Ken W Kinzler, Bert Vogelstein, Kathleen G Dickman, George J Netto
Publikováno v:
eLife, Vol 7 (2018)
Externí odkaz:
https://doaj.org/article/2a64088993e947c28fb98bda8c6de228
Autor:
Simeon U Springer, Chung-Hsin Chen, Maria Del Carmen Rodriguez Pena, Lu Li, Christopher Douville, Yuxuan Wang, Joshua David Cohen, Diana Taheri, Natalie Silliman, Joy Schaefer, Janine Ptak, Lisa Dobbyn, Maria Papoli, Isaac Kinde, Bahman Afsari, Aline C Tregnago, Stephania M Bezerra, Christopher VandenBussche, Kazutoshi Fujita, Dilek Ertoy, Isabela W Cunha, Lijia Yu, Trinity J Bivalacqua, Arthur P Grollman, Luis A Diaz, Rachel Karchin, Ludmila Danilova, Chao-Yuan Huang, Chia-Tung Shun, Robert J Turesky, Byeong Hwa Yun, Thomas A Rosenquist, Yeong-Shiau Pu, Ralph H Hruban, Cristian Tomasetti, Nickolas Papadopoulos, Ken W Kinzler, Bert Vogelstein, Kathleen G Dickman, George J Netto
Publikováno v:
eLife, Vol 7 (2018)
Current non-invasive approaches for detection of urothelial cancers are suboptimal. We developed a test to detect urothelial neoplasms using DNA recovered from cells shed into urine. UroSEEK incorporates massive parallel sequencing assays for mutatio
Externí odkaz:
https://doaj.org/article/035e9fc0aa4749039ab3ee51913706ab
Autor:
Yuxuan Wang, Karin Sundfeldt, Constantina Mateoiu, Ie-Ming Shih, Robert J Kurman, Joy Schaefer, Natalie Silliman, Isaac Kinde, Simeon Springer, Michael Foote, Björg Kristjansdottir, Nathan James, Kenneth W Kinzler, Nickolas Papadopoulos, Luis A Diaz, Bert Vogelstein
Publikováno v:
eLife, Vol 5 (2016)
We determined whether the mutations found in ovarian cancers could be identified in the patients' ovarian cyst fluids. Tumor-specific mutations were detectable in the cyst fluids of 19 of 23 (83%) borderline tumors, 10 of 13 (77%) type I cancers, and
Externí odkaz:
https://doaj.org/article/77bded7dc6b1436f8f889f8d7f7c42d4
Autor:
Jeanne, Tie, Joshua D, Cohen, Kamel, Lahouel, Serigne N, Lo, Yuxuan, Wang, Suzanne, Kosmider, Rachel, Wong, Jeremy, Shapiro, Margaret, Lee, Sam, Harris, Adnan, Khattak, Matthew, Burge, Marion, Harris, James, Lynam, Louise, Nott, Fiona, Day, Theresa, Hayes, Sue-Anne, McLachlan, Belinda, Lee, Janine, Ptak, Natalie, Silliman, Lisa, Dobbyn, Maria, Popoli, Ralph, Hruban, Anne Marie, Lennon, Nicholas, Papadopoulos, Kenneth W, Kinzler, Bert, Vogelstein, Cristian, Tomasetti, Peter, Gibbs, Susanne, Kosmider
Publikováno v:
New England Journal of Medicine. 386:2261-2272
The role of adjuvant chemotherapy in stage II colon cancer continues to be debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor recurrence-free survival, whereas its absence predicts a low risk of recurrence. The be
Autor:
Yuxuan Wang, Christopher Douville, Joshua D. Cohen, Austin Mattox, Sam Curtis, Natalie Silliman, Maria Popoli, Janine Ptak, Lisa Dobbyn, Nadine Nehme, Jonathan C. Dudley, Mahmoud Summers, Ming Zhang, Lan T. Ho-Pham, Bich N. H. Tran, Thach S. Tran, Tuan V. Nguyen, Chetan Bettegowda, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The analysis of cell-free DNA (cfDNA) from plasma offers great promise for the earlier detection of cancer. At present, changes in DNA sequence, methylation, or copy number are the most sensitive ways to detect the presence of cancer. To further incr
Autor:
Yuxuan Wang, Christopher Douville, Joshua D. Cohen, Austin Mattox, Sam Curtis, Natalie Silliman, Maria Popoli, Janine Ptak, Lisa Dobbyn, Nadine Nehme, Jonathan C. Dudley, Mahmoud Summers, Ming Zhang, Chetan Bettegowda, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein
The analysis of cell-free DNA (cfDNA) from plasma offers great promise for the earlier detection of cancer. At present, changes in DNA sequence, methylation, or copy number are the most sensitive ways to detect the presence of cancer. To further incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4beb46a894451db0bf0f939224cc019
https://doi.org/10.1101/2022.12.06.22283116
https://doi.org/10.1101/2022.12.06.22283116
Autor:
Brian J. Mog, Kenneth W. Kinzler, Jeanne Tie, Maria Popoli, Lisa Dobbyn, Christopher Douville, Peter Gibbs, Bert Vogelstein, Nickolas Papadopoulos, Cristian Tomasetti, Natalie Silliman, Joy Schaefer, Jonathan C. Dudley, Janine Ptak, Joshua D. Cohen
Publikováno v:
Nat Biotechnol
Identification and quantification of low-frequency mutations remain challenging despite improvements in the baseline error rate of next-generation sequencing technologies. Here, we describe a method, termed SaferSeqS, that addresses these challenges
Autor:
Christopher Douville, Austin K Mattox, Natalie Silliman, Janine Ptak, Lisa Dobbyn, Joy Schaefer, Maria Popoli, Cherie Blair, Kathy Judge, Kai Pollard, Christine Pratilas, Jaishri Blakeley, Fausto Rodriguez, Nickolas Papadopoulos, Allan Belzberg, Chetan Bettegowda
Publikováno v:
eLife. 11
Malignant peripheral nerve sheath tumors (MPNST) are the deadliest cancer that arises in individuals diagnosed with neurofibromatosis and account for nearly 5% of the 15,000 soft tissue sarcomas diagnosed in the United States each year. Comprised of
Autor:
Joshua D. Cohen, Lisa Dobbyn, Desmond Yip, Jeanne Tie, Maria Popoli, Peter Gibbs, Bert Vogelstein, Yuxuan Wang, Cristian Tomasetti, Iain Skinner, Janine Ptak, Kenneth W. Kinzler, Hui-Li Wong, Christos S. Karapetis, Natalie Silliman, Suzanne Kosmider, Nickolas Papadopoulos, Matthew Burge, Mary J. Schaeffer, Timothy J. Price, Rachel Wong, Lu Li, Andrew Haydon, Belinda Lee, Margaret Lee, Niall C. Tebbutt, Serigne Lo, Michael Christie
Publikováno v:
Int J Cancer
Studies in multiple solid tumor types have demonstrated the prognostic significance of ctDNA analysis after curative intent surgery. A combined analysis of data across completed studies could further our understanding of circulating tumor DNA (ctDNA)