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Autor:
Erkan Tuncay, Ivan Gando, Jian-Yi Huo, Gautham Yepuri, Natalie Sampler, Belma Turan, Hua-Qian Yang, Ravichandran Ramasamy, William A. Coetzee
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C1017-C1027
Sirtuins are NAD+-dependent deacetylases with beneficial roles in conditions relevant to human health, including metabolic disease, type II diabetes, obesity, cancer, aging, neurodegenerative diseases, and cardiac ischemia. Since ATP-sensitive K+ (KA