Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Natalie S. Rudolph"'
1
Lessons from randomized phase III studies with active cancer immunotherapies--outcomes from the 2006 meeting of the Cancer Vaccine Consortium (CVC)
Autor: Brent A. Blumenstein, Axel Hoos, Kerry Wentworth, Natalie S. Rudolph, Hyam I. Levitsky, L. H. Finke
Publikováno v: Vaccine. 25
After years of effort to develop active cancer immunotherapies, seven candidate products achieved promising results in phase I/II studies that triggered phase III randomized studies. One candidate to date has received an approvable letter from the Un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a172d7156495ac71853483c25625ad61
https://pubmed.ncbi.nlm.nih.gov/17916465
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2
Biopharmaceutical production in transgenic livestock
Autor: Natalie S. Rudolph
Publikováno v: Trends in biotechnology. 17(9)
The production of recombinant human proteins in the milk of transgenic dairy animals offers a safe, renewable source of commercially important proteins that cannot be produced as efficiently in adequate quantities by other methods. A decade of succes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6632321a95fc6252d1b4ef6360710862
https://pubmed.ncbi.nlm.nih.gov/10461183
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3
Single-cell analysis of the relationship among transferrin receptors, proliferation, and cell cycle phase in K562 cells
Autor: Betsy M. Ohlsson-Wilhelm, Peter T. Rowley, James F. Leary, Natalie S. Rudolph
Publikováno v: Cytometry. 6:151-158
Multiparameter single-cell analysis by flow cytometry was used to distinguish between size-related changes in K562 cell transferrin receptor (TfR) expression and changes in membrane receptor density throughout the cell cycle and over time in culture.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbfea5d0b036606cd9c33e29f0063f1
https://doi.org/10.1002/cyto.990060211
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4
Linkage disequilibrium between theT/t complex andPgk-2 in wild mice
Autor: John L. VandeBerg, Natalie S. Rudolph
Publikováno v: Journal of Experimental Zoology. 217:455-458
Linkage disequilibrium between the T/t complex and Pgk-2 - two loci flanking the murine major histocompatibility complex on chromosome 17 - has been found in a population of wild mice. By subjecting 78 wild males to progeny testing, we extracted 15 r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b255f71ab3db4decfd5dd52090546e18
https://doi.org/10.1002/jez.1402170319
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5
Restriction of PGK-B to spermatogenic cells: Evidence from experimentally cryptorchid mice
Autor: Natalie S. Rudolph, John L. VandeBerg
Publikováno v: Developmental Genetics. 1:341-353
The hypothesis that PGK-B, like LDH-C4, is restricted to spermatogenic cells was explored by examining isozyme patterns in testes from mice depleted of germinal cells by surgical cryptorchism. In experimentally cryptorchized C57BL/10Sn males, decline
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ab217229f79ca511b511911a0545e6e
https://doi.org/10.1002/dvg.1020010407
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6
Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia
Autor: Natalie S. Rudolph, Samuel A. Latt
Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 211:31-41
Flow cytometric analysis of 5-bromodeoxyuridine (BrdU) incorporation during DNA synthesis was used to characterize the effects of X-rays on cell-cycle kinetics in the DNA-repair deficiency disease ataxia telangiectasia (AT). Cultured fibroblasts from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39269288aac201a3977a32bd2a7d859
https://doi.org/10.1016/0027-5107(89)90104-8
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8
Hemin preferentially stimulates synthesis of alpha-globin in K562 human erythroleukemia cells
Autor: Natalie S. Rudolph, Peter T. Rowley, Barbara A. Farley, Sandra Labella, Barbara A. Kosciolek, Betsy M. Ohlsson-Wilhelm
Publikováno v: Blood. 59:1098-1102
K562 human erythroleukemia cells are an established cell line derived from an adult with chronic myelogenous leukemia. Hemin stimulates their synthesis of embryonic and fetal hemoglobins. We have found that their globin synthetic pattern depends on t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::657e71a6ca031f700cd0ed71c8f3ca5b
https://doi.org/10.1182/blood.v59.5.1098.1098
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9
Identification of ataxia telangiectasia heterozygotes by flow cytometric analysis of X-ray damage
Autor: John B. Little, Samuel A. Latt, Natalie S. Rudolph, Hatsumi Nagasawa
Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 211:19-29
Flow cytometry was used to identify heterozygotes for the autosomal recessive DNA-repair deficiency disease ataxia telangiectasia (AT). Confluent G0/G1 fibroblasts from 4 homozygotes (at/at), 5 obligate heterozygotes (at/+) and 7 presumed normal cont
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b71b11c7b341f54eff0f21fd5e6279a
https://doi.org/10.1016/0027-5107(89)90103-6
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10
Erythroid induction of K562 human leukemia cells: enhancement by purines
Autor: Natalie S. Rudolph, Barbara A. Farley, Betsy M. Ohlsson-Wilhelm, Peter T. Rowley
Publikováno v: Archives of biochemistry and biophysics. 239(2)
K562 cells are human leukemia cells inducible for hemoglobin synthesis by a variety of agents. This report demonstrates that hypoxanthine, which alone has no inductive effect, enhances induction by thymidine, resulting in a greater absolute, as well
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a78d04888fea75bc459eb8b3fdc9e15
https://pubmed.ncbi.nlm.nih.gov/4004276
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