Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Natalie S Firmino"'
Autor:
Natalie S Firmino, Rachel A Cederberg, Che-Min Lee, Rocky Shi, Brennan J Wadsworth, S Elizabeth Franks, Kiersten N Thomas, Lisa R Decotret, Kevin L Bennewith
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Hypoxia develops in germinal centers (GCs) induced by model antigens; however, it is unknown whether tumor-reactive GCs are also hypoxic. We identified GC hypoxia in lymph nodes (LNs) draining murine mammary tumors and lethally irradiated tumor cells
Externí odkaz:
https://doaj.org/article/564080d65da14b9aa13ca29d3b8f43bd
Autor:
Brennan J. Wadsworth, Kiersten N Thomas, Kevin L. Bennewith, S. Elizabeth Franks, Natalie S. Firmino, Rachel A. Cederberg, Che-Min Lee, Rocky Shi, Lisa R. Decotret
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology
article-version (VoR) Version of Record
Hypoxia develops in germinal centers (GCs) induced by model antigens; however, it is unknown whether tumor-reactive GCs are also hypoxic. We identified GC hypoxia in lymph nodes (LNs) draining murine mammary tumors and lethally irradiated tumor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39540298db181f1f63f201e1736f59a5
https://doaj.org/article/564080d65da14b9aa13ca29d3b8f43bd
https://doaj.org/article/564080d65da14b9aa13ca29d3b8f43bd
Autor:
Rachel A. Cederberg, Francois Benard, Nadine Colpo, Jinhe Pan, Kevin L. Bennewith, Brennan J. Wadsworth, S. Elizabeth Franks, Kuo-Shyan Lin, Che-Min Lee, Natalie S. Firmino
Publikováno v:
Cancer letters. 493
Hypoxic tumour cells are radiation-resistant and are associated with poor therapeutic outcome. A poorly understood source of tumour hypoxia is unstable perfusion, which exposes tumour cells to varying oxygen tensions over time creating "transiently"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92bb639528006b1574548dd9f6cbf81
https://pubmed.ncbi.nlm.nih.gov/32763272
https://pubmed.ncbi.nlm.nih.gov/32763272
Autor:
Katey S. S. Enfield, Wan L. Lam, David A. Rowbotham, Victor D. Martinez, Natalie S. Firmino, Kevin L. Bennewith
Publikováno v:
Oral Oncology. 55:43-48
Summary Objectives As HPV-induced cases of oral malignancy increase, it is important to understand the molecular differences between HPV positive and negative head and neck squamous cell carcinoma (HNSCC). PIWI-interacting RNAs (piRNAs) are a class o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f45be817a80ad27b90eb8b5273a8e2c
https://doi.org/10.1016/j.oraloncology.2016.01.012
https://doi.org/10.1016/j.oraloncology.2016.01.012
Autor:
Min Hee Oh, Bryant T. Harbourne, Arun M. Unni, Rachel A. Cederberg, Jenna L. Collier, Kevin L. Bennewith, Vivian Lam, Ninan Abraham, Elizabeth Franks, Jennifer Luu, Liz Halvorsen, William W. Lockwood, Gerry Krystal, Etienne Melese, Natalie S. Firmino
Publikováno v:
Cancer Immunology Research. 8:A38-A38
Lung cancer development is driven by the expression of mutant oncogenes, with EGFR and KRAS being the most frequent mutations in lung adenocarcinoma. However, these mutations alone are not sufficient for tumorigenesis, and additional factors influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4426ba6f623eec88c9f9f56cf57580cb
https://doi.org/10.1158/2326-6074.tumimm18-a38
https://doi.org/10.1158/2326-6074.tumimm18-a38
Autor:
Marcel B. Bally, Gemma M. Ryan, Kevin L. Bennewith, Ada W. Y. Leung, Roger Gilabert-Oriol, Natalie S. Firmino
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2922 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Tumours are complex systems of genetically diverse malignant cells that proliferate in the presence of a heterogeneous microenvironment consisting of host derived microvasculature, stromal, and immune cells. The components of the tumour microenvironm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d49cab0c91948befe50a35e14ff15ca
http://www.mdpi.com/1422-0067/19/10/2922
http://www.mdpi.com/1422-0067/19/10/2922
Autor:
Erin A. Marshall, Kevin W. Ng, Christine Anderson, Brennan J. Wadsworth, Victor D. Martinez, Wan L. Lam, Kevin L. Bennewith, Natalie S. Firmino
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Hypoxia promotes tumour aggressiveness and reduces patient survival. A spectrum of poor outcome among patients with hypoxic tumours suggests that additional factors modulate how tumours respond to hypoxia. PIWI-interacting RNAs (piRNAs) are small non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15ff5b941f8fab8a46c142a9f0a1a0c
https://doi.org/10.1038/s41598-017-18462-z
https://doi.org/10.1038/s41598-017-18462-z
Autor:
Kristen Reipas, Sandra E. Dunn, Natalie S. Firmino, Anna L. Stratford, Rachel Berns, Kaiji Hu, Alastair H. Davies
Publikováno v:
Oncotarget
The triple-negative breast cancer (TNBC) subtype is enriched in cancer stem cells (CSCs) and clinically correlated with the highest rate of recurrence. Several studies implicate the RSK pathway as being pivotal for the growth and proliferation of CSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8859a7981d7b19a951e84e25bfc7940e
https://doi.org/10.18632/oncotarget.4135
https://doi.org/10.18632/oncotarget.4135
Autor:
Wan L. Lam, Victor D. Martinez, Erin A. Marshall, Natalie S. Firmino, Adam P. Sage, Kevin W. Ng, Kevin L. Bennewith
Publikováno v:
Scientific Data
Only 3% of the transcribed human genome is translated into protein, and small non-coding RNAs from these untranslated regions have demonstrated critical roles in transcriptional and translational regulation of proteins. Here, we provide a resource th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cf7b6eddbb2870820ae325f96ce7bf
https://pubmed.ncbi.nlm.nih.gov/29064465
https://pubmed.ncbi.nlm.nih.gov/29064465
Autor:
Anna L. Stratford, Rachel Berns, Abbas Fotovati, Kaiji Hu, Arezoo Astanehe, Christopher A. Maxwell, Sandra E. Dunn, Kristen Reipas, Natalie S. Firmino, Mary Rose Pambid, Alastair H. Davies, Gordon B. Mills
Publikováno v:
Stem Cells. 32:1437-1450
There is growing evidence that cancer-initiation could result from epigenetic changes. Y-box binding protein-1 (YB-1) is a transcription/translation factor that promotes the formation of tumors in transgenic mice; however, the underlying molecular ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4fa5f8466f2cdaf94849389b927e5f
https://doi.org/10.1002/stem.1707
https://doi.org/10.1002/stem.1707