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pro vyhledávání: '"Natalie Rutz"'
Autor:
Christopher van Hoorebeke, Kevin Yang, Samuel J. Mussetter, Grant Koch, Natalie Rutz, R. Scott Lokey, Phillip Crews, Theodore R. Holman
Publikováno v:
ACS omega. 7(47)
Regulation of lipoxygenase (LOX) activity is of great interest due to the involvement of the various LOX isoforms in the inflammatory process and hence many diseases. The bulk of investigations have centered around the discovery and design of inhibit
Autor:
Steven C. Perry, Christopher van Hoorebeke, James Sorrentino, Leslie Bautista, Oluwayomi Akinkugbe, William S. Conrad, Natalie Rutz, Theodore R. Holman
Publikováno v:
Archives of Biochemistry and Biophysics. 727:109317
Human 15-lipoxygenases (LOX) are critical enzymes in the inflammatory process, producing various pro-resolution molecules, such as lipoxins and resolvins, but the exact role each of the two 15-LOXs in these biosynthetic pathways remains elusive. Prev