Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Natalie R Powers"'
Autor:
Natalie R Powers, Emil D Parvanov, Christopher L Baker, Michael Walker, Petko M Petkov, Kenneth Paigen
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006146 (2016)
In many mammals, including humans and mice, the zinc finger histone methyltransferase PRDM9 performs the first step in meiotic recombination by specifying the locations of hotspots, the sites of genetic recombination. PRDM9 binds to DNA at hotspots t
Externí odkaz:
https://doaj.org/article/ef39fb2063b4469d869565c64bbbe09d
Autor:
John D Eicher, Natalie R Powers, Kelly Cho, Laura L Miller, Kathryn L Mueller, Susan M Ring, J Bruce Tomblin, Jeffrey R Gruen
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63762 (2013)
Language impairment (LI) and reading disability (RD) are common pediatric neurobehavioral disorders that frequently co-occur, suggesting they share etiological determinants. Recently, our group identified prenatal nicotine exposure as a factor for RD
Externí odkaz:
https://doaj.org/article/96237115843749ad882b7861ff42d897
Autor:
Beth L. Dumont, Kenneth Paigen, Natalie R. Powers, Raman Akinyanju Lawal, Catherine Brunton, Tanmoy Bhattacharyya, Petko M. Petkov, Mary Ann Handel, Chihiro Emori, Ewelina Bolcun-Filas
Publikováno v:
Science Advances
Sex-specific modulation of a meiotic DNA damage checkpoint limits the requirement for PRDM9 in mammalian fertility.
In many mammals, genomic sites for recombination are determined by the histone methyltransferase PRMD9. Some mouse strains lackin
In many mammals, genomic sites for recombination are determined by the histone methyltransferase PRMD9. Some mouse strains lackin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b595c71e0f96cf3beb53d9fedd778e
https://doi.org/10.1101/2020.03.10.985358
https://doi.org/10.1101/2020.03.10.985358
Autor:
Dylan M. Rausch, Gregory W. Carter, Hui Tian, Bo Ji, Michael D. Walker, Christopher L. Baker, Catrina Spruce, Petko M. Petkov, Kenneth Paigen, Kwangbom Choi, Seda Arat, Natalie R. Powers, Pavlina Petkova, Guruprasad Ananda
While much is known about the enzymes that deposit and remove epigenetic modifications, less is known about the trans-acting system that determines when and where these modifications occur. By looking at four diverse... The epigenetic landscape varie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e428393ac7e3a46c33e523c6cefc569
https://doi.org/10.1101/322081
https://doi.org/10.1101/322081
Autor:
Christopher Geissler, Jeffrey G. Malins, Andrew K. Adams, Jeffrey R. Gruen, Mellissa M C DeMille, Kevin Tang, Natalie R. Powers, Beatrice M. Bowen, Chintan M. Mehta, Jan C. Frijters, Dongnhu T. Truong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Languages evolve rapidly due to an interaction between sociocultural factors and underlying phonological processes that are influenced by genetic factors. DCDC2 has been strongly associated with core components of the phonological proces
Autor:
Natalie R. Powers, Shelley D. Smith, Richard Boada, Barbara A. Lewis, Bruce F. Pennington, John D. Eicher, Sudha K. Iyengar, Fenghua Deng, Catherine M. Stein, Jeffrey R. Gruen, Allison A vrich Ciesla
Publikováno v:
Genes, Brain, and Behavior
A major milestone of child development is the acquisition and use of speech and language. Communication disorders, including speech sound disorder (SSD), can impair a child's academic, social and behavioral development. Speech sound disorder is a com
Autor:
Petko M. Petkov, Tanmoy Bhattacharyya, Mary Ann Handel, Michael G. Walker, Catherine Brunton, Alexander Fine, Natalie R. Powers
Publikováno v:
Curr Biol
Meiotic recombination is required for correct segregation of chromosomes to gametes and to generate genetic diversity. In mice and humans, DNA double-strand breaks (DSBs) are initiated by SPO11 at recombination hotspots activated by PRDM9-catalyzed h
Autor:
Terry L. Jernigan, John D. Eicher, Nicholas J. Schork, B. St Pourcain, Susan M. Ring, Cinnamon S. Bloss, Brian Keating, Tal Kenet, Natacha Akshoomoff, Elizabeth R. Sowell, David N. Kennedy, B. J. Casey, Laura L. Miller, Anders M. Dale, Thomas Ernst, Burcu F. Darst, Ondrej Libiger, Sarah S. Murray, David G. Amaral, G Davey Smith, Linda Chang, Natalie R. Powers, Timothy T. Brown, Jean A. Frazier, Joshua M. Kuperman, Stewart H. Mostofsky, Jeffrey R. Gruen, Donald J. Hagler, Walter E. Kaufmann, Hauke Bartsch
Publikováno v:
Genes, Brain and Behavior
Genes, Brain, and Behavior
Genes, Brain, and Behavior
Written and verbal languages are neurobehavioral traits vital to the development of communication skills. Unfortunately, disorders involving these traits-specifically reading disability (RD) and language impairment (LI)-are common and prevent affecte
Autor:
Christopher L. Baker, Petko M. Petkov, Natalie R. Powers, Kenneth Paigen, Emil D Parvanov, Michael G. Walker
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 6, p e1006146 (2016)
PLoS Genetics, Vol 12, Iss 6, p e1006146 (2016)
In many mammals, including humans and mice, the zinc finger histone methyltransferase PRDM9 performs the first step in meiotic recombination by specifying the locations of hotspots, the sites of genetic recombination. PRDM9 binds to DNA at hotspots t
Autor:
Joel Gelernter, Sharna D. Jamadar, Shashwath A. Meda, Jeffrey R. Gruen, Godfrey D. Pearlson, Natalie R. Powers
Publikováno v:
Schizophrenia Research. 129:141-148
Individuals with schizophrenia show a broad range of language impairments, including reading difficulties. A recent structural MRI (sMRI) study linked these difficulties to structural abnormalities in language-related regions ( Leonard et al., 2008 )