Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Natalie Ng"'
Autor:
Shaliny Ramachandran, Tiffany S. Ma, Jon Griffin, Natalie Ng, Iosifina P. Foskolou, Ming-Shih Hwang, Pedro Victori, Wei-Chen Cheng, Francesca M. Buffa, Katarzyna B. Leszczynska, Sherif F. El-Khamisy, Natalia Gromak, Ester M. Hammond
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Hypoxia induces a change in transcriptional response in mammalian cells. Here the authors reveal a role for the RNA/DNA helicase Senataxin in protecting cells from DNA damage induced during transcription in hypoxia.
Externí odkaz:
https://doaj.org/article/53d171bea0d243d0a270df932d095042
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 4, p e1006683 (2019)
The actin family of cytoskeletal proteins is essential to the physiology of virtually all archaea, bacteria, and eukaryotes. While X-ray crystallography and electron microscopy have revealed structural homologies among actin-family proteins, these te
Externí odkaz:
https://doaj.org/article/9de135470a34456aa9a8bd68297d768c
Autor:
Ana R. Pereira, Jen Hsin, Ewa Król, Andreia C. Tavares, Pierre Flores, Egbert Hoiczyk, Natalie Ng, Alex Dajkovic, Yves V. Brun, Michael S. VanNieuwenhze, Terry Roemer, Rut Carballido-Lopez, Dirk-Jan Scheffers, Kerwyn Casey Huang, Mariana G. Pinho
Publikováno v:
mBio, Vol 7, Iss 5 (2016)
ABSTRACT A mechanistic understanding of the determination and maintenance of the simplest bacterial cell shape, a sphere, remains elusive compared with that of more complex shapes. Cocci seem to lack a dedicated elongation machinery, and a spherical
Externí odkaz:
https://doaj.org/article/f16c8280e23f43a6a894f35a18b85773
Autor:
Amanda J. Wright, H. Douglas Goff, Alejandro G. Marangoni, Iris J. Joye, Natalie Ng, Michael A. Rogers, Saeed M. Ghazani, Peter X. Chen
Publikováno v:
Food & Function. 10:8195-8207
Altering sn-fatty acid position of glycerol mono-oleate (GMO) from sn-1 to sn-2 decreases fatty acid bioaccessibility by 25.9% providing possible strategies to tailor lipemic responses of food emulsions. Lipid digestion kinetics and fatty acid bioacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4471fe57af39921ddc97da458186c9
https://doi.org/10.1039/c9fo02210d
https://doi.org/10.1039/c9fo02210d
Autor:
Ming-Shih Hwang, Wei-Chen Cheng, Tiffany S Ma, Katarzyna B. Leszczynska, Pedro Victori, Francesca M. Buffa, Shaliny Ramachandran, Natalia Gromak, Natalie Ng, Iosifina P. Foskolou, Ester M. Hammond
The levels of hypoxia associated with resistance to radiotherapy significantly impact cancer patient prognosis. These levels of hypoxia initiate a unique transcriptional response with the rapid activation of numerous transcription factors in a backgr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17dfc2fa1cff565d5c8776bc33f25b2d
https://doi.org/10.1101/2020.05.24.113548
https://doi.org/10.1101/2020.05.24.113548
Publikováno v:
The FEBS Journal. 285:1563-1571
The term hypoxia refers to any condition where insufficient oxygen is available and therefore encompasses a range of actual oxygen concentrations. The regions of tumours adjacent to necrotic areas are at almost anoxic levels and are known to be extre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe6a26e4ee269ab9a06f3baed8e3ae9
https://doi.org/10.1111/febs.14377
https://doi.org/10.1111/febs.14377
Autor:
Robert John Walsh, Rebecca Ong, Seng Wee Cheo, Peter Q.J. Low, Aishwarya Jayagopal, Matilda Lee, Natalie Ngoi, Samuel G. Ow, Andrea L.A. Wong, Siew Eng Lim, Yi Wan Lim, Valerie Heong, Raghav Sundar, Ross A. Soo, Cheng Ean Chee, Wei Peng Yong, Boon Cher Goh, Soo Chin Lee, David S.P. Tan, Joline S.J. Lim
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMolecular profiling of metastatic breast cancer (MBC) through the widespread use of next-generation sequencing (NGS) has highlighted actionable mutations and driven trials of targeted therapy matched to tumour molecular profiles, with imp
Externí odkaz:
https://doaj.org/article/98dbdbab3f7349b688320adc069900de
Autor:
Natalie Ng, Alan P. Boyle, Shengcheng Dong, Sierra S. Nishizaki, Cody Morterud, Robert S. Porter, Courtney Asman, Jessica A. Switzenberg, Colten Williams
Publikováno v:
Bioinformatics
Motivation Genome-wide association studies have revealed that 88% of disease-associated single-nucleotide polymorphisms (SNPs) reside in noncoding regions. However, noncoding SNPs remain understudied, partly because they are challenging to prioritize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e633a6002d45842672b70b247682715
https://europepmc.org/articles/PMC7999143/
https://europepmc.org/articles/PMC7999143/
Autor:
Alan P. Boyle, Colten Williams, Natalie Ng, Shengcheng Dong, Cody Morterud, Sierra S. Nishizaki
GWAS have revealed that 88% of disease associated SNPs reside in noncoding regions. However, noncoding SNPs remain understudied, partly because they are challenging to prioritize for experimental validation. To address this deficiency, we developed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d339364ab9c4b7b7fc37e614e860a3