Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Natalie N. C. Shih"'
Autor:
Matthew R. Lawrence-Paul, Tien-chi Pan, Dhruv K. Pant, Natalie N. C. Shih, Yan Chen, George K. Belka, Michael Feldman, Angela DeMichele, Lewis A. Chodosh
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background Evolutionary models of breast cancer progression differ on the extent to which metastatic potential is pre-encoded within primary tumors. Although metastatic recurrences often harbor putative driver mutations that are not detected
Externí odkaz:
https://doaj.org/article/e39183bc9dda4422b08a07e9f44a1073
Autor:
Sagarika Banerjee, Zhi Wei, Tian Tian, Dipayan Bose, Natalie N. C. Shih, Michael D. Feldman, Thaer Khoury, Angela De Michele, Erle S. Robertson
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-14 (2021)
Abstract Alterations to the natural microbiome are linked to different diseases, and the presence or absence of specific microbes is directly related to disease outcomes. We performed a comprehensive analysis with unique cohorts of the four subtypes
Externí odkaz:
https://doaj.org/article/48080ec997f14e9db4382388ebb6ce47
Autor:
Pasquale Sansone, Claudio Ceccarelli, Marjan Berishaj, Qing Chang, Vinagolu K. Rajasekhar, Fabiana Perna, Robert L. Bowman, Michele Vidone, Laura Daly, Jennifer Nnoli, Donatella Santini, Mario Taffurelli, Natalie N. C. Shih, Michael Feldman, Jun J. Mao, Christopher Colameco, Jinbo Chen, Angela DeMichele, Nicola Fabbri, John H. Healey, Monica Cricca, Giuseppe Gasparre, David Lyden, Massimiliano Bonafé, Jacqueline Bromberg
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
ER+ breast cancer patients treated with endocrine therapies often acquire resistance and develop metastasis. In this study, the authors demonstrate that endocrine therapies can promote the self-renewal of CD133hi/ERlodrug resistant cells with metasta
Externí odkaz:
https://doaj.org/article/0f73773c836b47a9b54b97e9c2ac1634
Autor:
Zhi Wei, S. Banerjee, Angela De Michele, Erle S. Robertson, Natalie N. C. Shih, Michael Feldman, Thaer Khoury, Dipayan Bose, Tian Tian
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Alterations to the natural microbiome are linked to different diseases, and the presence or absence of specific microbes is directly related to disease outcomes. We performed a comprehensive analysis with unique cohorts of the four subtypes of breast
Autor:
George Lee, Rachel Sparks, Sahirzeeshan Ali, Natalie N C Shih, Michael D Feldman, Elaine Spangler, Timothy Rebbeck, John E Tomaszewski, Anant Madabhushi
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97954 (2014)
Quantitative histomorphometry (QH) refers to the application of advanced computational image analysis to reproducibly describe disease appearance on digitized histopathology images. QH thus could serve as an important complementary tool for pathologi
Externí odkaz:
https://doaj.org/article/ac15bf95ad0a413c972f37e6b8c46d4b
Autor:
Michael Feldman, Sacheth Chandramouli, Jessica Kim, Jesse K. McKenney, Sanjay Gupta, Kaustav Bera, David I. Lee, Priti Lal, Francesca Khani, Mohammed Shahait, Ayah El-Fahmawi, Pingfu Fu, Natalie N. C. Shih, Brian D. Robinson, Andrew Janowczyk, Nafiseh Janaki, Patrick Leo, Anant Madabhushi, Xavier Farre, Kosj Yamoah, Timothy R. Rebbeck, Robin Elliott
Publikováno v:
Eur Urol Focus
European urology focus, vol 7, iss 4
European urology focus, vol 7, iss 4
Background The presence of invasive cribriform adenocarcinoma (ICC), an expanse of cells containing punched-out lumina uninterrupted by stroma, in radical prostatectomy (RP) specimens has been associated with biochemical recurrence (BCR). However, IC
Autor:
Aaron Solomon, Noah Goodman, Dhruv K. Pant, Michael Feldman, Kara N. Maxwell, Matt R. Paul, S. William Stavropoulos, Tien-chi Pan, Yan Chen, Natalie N. C. Shih, George K. Belka, Danielle Soucier-Ernst, Kyra L. Harvey, Lewis A. Chodosh, Candace Clark, Angela DeMichele, David B. Lieberman, Jennifer J.D. Morrissette
Publikováno v:
J Clin Invest
Nearly all breast cancer deaths result from metastatic disease. Despite this, the genomic events that drive metastatic recurrence are poorly understood. We performed whole-exome and shallow whole-genome sequencing to identify genes and pathways prefe
Autor:
Mark A. Rosen, John E. Tomaszewski, Natalie N. C. Shih, Li-Ping Wang, Mirabela Rusu, Anant Madabhushi, Amy Ziober, Asha Singanamalli, Michael Feldman, Rachel Sparks
Publikováno v:
Journal of Magnetic Resonance Imaging. 43:149-158
Background: To identify computer extracted in vivo dynamic contrast enhanced (DCE) MRI markers associated with quantitative histomorphometric (QH) characteristics of microvessels and Gleason scores (GS) in prostate cancer. Methods: This study conside
Autor:
Asha Singanamalli, Anant Madabhushi, Timothy R. Rebbeck, John E. Tomaszewski, Michael Feldman, Elaine Spangler, Stephen R. Master, Haibo Wang, George Lee, Natalie N. C. Shih
Publikováno v:
IEEE Transactions on Medical Imaging. 34:284-297
In this work, we present a new methodology to facilitate prediction of recurrent prostate cancer (CaP) following radical prostatectomy (RP) via the integration of quantitative image features and protein expression in the excised prostate. Creating a
Autor:
Michael Feldman, Robin Elliott, Anant Madabhushi, Sanjay Gupta, Patrick Leo, Natalie N. C. Shih
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Site variation in fixation, staining, and scanning can confound automated tissue based image classifiers for disease characterization. In this study we incorporated stability into four feature selection methods for identifying the most robust and dis