Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Natalie M. Landry"'
Autor:
Raghu S Nagalingam, Sikta Chattopadhyaya, Danah S Al-Hattab, David Y C Cheung, Leah Y Schwartz, Sayantan Jana, Nina Aroutiounova, D Allison Ledingham, Teri L Moffatt, Natalie M Landry, Rushita A Bagchi, Ian M C Dixon, Jeffrey T Wigle, Gavin Y Oudit, Zamaneh Kassiri, Davinder S Jassal, Michael P Czubryt
Publikováno v:
European Heart Journal. 43:4739-4750
Aims In response to pro-fibrotic signals, scleraxis regulates cardiac fibroblast activation in vitro via transcriptional control of key fibrosis genes such as collagen and fibronectin; however, its role in vivo is unknown. The present study assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3e1676f5ff089c0cab8c5222b495a4
https://doi.org/10.1093/eurheartj/ehac362
https://doi.org/10.1093/eurheartj/ehac362
Autor:
Peter A. Cattini, Michael P. Czubryt, Davinder S. Jassal, David Cheung, Barbara E. Nickel, Robert R. Fandrich, Elissavet Kardami, Raghu S. Nagalingam, Ian M.C. Dixon, Navid Koleini, Natalie M. Landry
Publikováno v:
Cell and Tissue Research. 385:753-768
Fibroblast growth factor 2 (FGF2), produced as high (Hi-) and low (Lo-) molecular weight isoforms, is implicated in cardiac response to injury. The role of endogenous FGF2 isoforms during chronic stress is not well defined. We investigated the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84604ecee03ebf92d2631fa2b1401a34
https://doi.org/10.1007/s00441-021-03465-0
https://doi.org/10.1007/s00441-021-03465-0
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2299
Two-dimensional cell culture is the primary method employed for proof-of-concept studies in most molecular biology labs. While immortalized cell lines are convenient and easy to maintain for extended periods in vitro, their inability to accurately re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca0399844a3559275437783763f58ab8
https://pubmed.ncbi.nlm.nih.gov/34028743
https://pubmed.ncbi.nlm.nih.gov/34028743
Autor:
Ian M.C. Dixon, Thomas W. Meier, Robert R. Fandrich, Krista L. Filomeno, Todd A. Duhamel, Sunil G. Rattan, Elissavet Kardami, Navid Koleini, Sarah J. Foran, Simon C. Meier, Claire F. Meier, Natalie M. Landry
Publikováno v:
Basic Research in Cardiology
We have previously shown that overexpression of SKI, an endogenous TGF-β1 repressor, deactivates the pro-fibrotic myofibroblast phenotype in the heart. We now show that SKI also functions independently of SMAD/TGF-β signaling, by activating the Hip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8056941623b3cd6db791b339e12f41a2
https://doi.org/10.1007/s00395-021-00865-9
https://doi.org/10.1007/s00395-021-00865-9
Autor:
Navid, Koleini, Barbara E, Nickel, Raghu S, Nagalingam, Natalie M, Landry, Robert R, Fandrich, David Y C, Cheung, Ian M, Dixon, Michael P, Czubryt, Davinder S, Jassal, Peter A, Cattini, Elissavet, Kardami
Publikováno v:
Cell and tissue research. 385(3)
Fibroblast growth factor 2 (FGF2), produced as high (Hi-) and low (Lo-) molecular weight isoforms, is implicated in cardiac response to injury. The role of endogenous FGF2 isoforms during chronic stress is not well defined. We investigated the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59e8067b0143dede31da8264751d36a7
https://pubmed.ncbi.nlm.nih.gov/34057573
https://pubmed.ncbi.nlm.nih.gov/34057573
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613818
Two-dimensional cell culture is the primary method employed for proof-of-concept studies in most molecular biology labs. While immortalized cell lines are convenient and easy to maintain for extended periods in vitro, their inability to accurately re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da7e9a10d39ddcb51ce1b8bc314233a5
https://doi.org/10.1007/978-1-0716-1382-5_13
https://doi.org/10.1007/978-1-0716-1382-5_13
Autor:
Natalie M. Landry, Danah S. Al-Hattab, Raghu S. Nagalingam, Michael P. Czubryt, Hamza A. Safi, Ian M.C. Dixon, Jeffrey T. Wigle, Rushita A. Bagchi
Publikováno v:
Journal of Molecular and Cellular Cardiology. 120:64-73
Remodeling of the cardiac extracellular matrix is responsible for a number of the detrimental effects on heart function that arise secondary to hypertension, diabetes and myocardial infarction. This remodeling consists both of an increase in new matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ddd60f739055de9f4426d87e6cc961
https://doi.org/10.1016/j.yjmcc.2018.05.004
https://doi.org/10.1016/j.yjmcc.2018.05.004
Autor:
Robert R. Fandrich, Elissavet Kardami, Peter A. Cattini, Natalie M. Landry, Raghu S. Nagalingam, Ian M.C. Dixon, Barbara E. Nickel, Navid Koleini, Michael P. Czubryt
Publikováno v:
Circulation Research. 125
Fibroblast growth factor 2 (FGF2) is implicated in normal cardiac development as well as cardiac pathophysiology; however, FGF2 exist as multiple high and low molecular weight isoforms. While endogenous low molecular weight FGF2 (Lo-FGF2) is cardiopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d0dc812b59050e9afa9d2270e753b0d
https://doi.org/10.1161/res.125.suppl_1.838
https://doi.org/10.1161/res.125.suppl_1.838
Publikováno v:
Advances in experimental medicine and biology. 1132
Cardiac muscle (the myocardium) is a unique arrangement of atria and ventricles that are spatially and electrically separated by a fibrous border. The spirally-arranged myocytes in both left and right ventricles are tethered by the component molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e7ed9b51910caf41ce72aea85fe287d
https://pubmed.ncbi.nlm.nih.gov/31037622
https://pubmed.ncbi.nlm.nih.gov/31037622
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::411a26204bc745aea7ac1f78fb055788
https://doi.org/10.1096/fasebj.2019.33.1_supplement.832.8
https://doi.org/10.1096/fasebj.2019.33.1_supplement.832.8