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Autor:
Natalie M. Hawco, Suk K. Hong, Patrick I. Brown, Gary O. Rankin, Monica A. Valentovic, Dianne K. Anestis
Publikováno v:
Toxicology. 110:17-25
Among N -(halophenyl)succinimides, N -(3,5-dichlorophenyl)succinimide (NDPS) is a potent nephrotoxicant as well as an agricultural fungicide. Although two chloride groups on the phenyl ring are essential to induce optimal nephrotoxicity, the role of