Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Natalie L. Roberts"'
Autor:
Paul M. O’Neill, Richard K. Amewu, Susan A. Charman, Sunil Sabbani, Nina F. Gnädig, Judith Straimer, David A. Fidock, Emma R. Shore, Natalie L. Roberts, Michael H.-L. Wong, W. David Hong, Chandrakala Pidathala, Chris Riley, Ben Murphy, Ghaith Aljayyoussi, Francisco Javier Gamo, Laura Sanz, Janneth Rodrigues, Carolina Gonzalez Cortes, Esperanza Herreros, Iñigo Angulo-Barturén, María Belén Jiménez-Díaz, Santiago Ferrer Bazaga, María Santos Martínez-Martínez, Brice Campo, Raman Sharma, Eileen Ryan, David M. Shackleford, Simon Campbell, Dennis A. Smith, Grennady Wirjanata, Rintis Noviyanti, Ric N. Price, Jutta Marfurt, Michael J. Palmer, Ian M. Copple, Amy E. Mercer, Andrea Ruecker, Michael J. Delves, Robert E. Sinden, Peter Siegl, Jill Davies, Rosemary Rochford, Clemens H. M. Kocken, Anne-Marie Zeeman, Gemma L. Nixon, Giancarlo A. Biagini, Stephen A. Ward
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Artemisinin-resistantPlasmodium is an increasing problem. Here, using a medicinal chemistry programme, the authors identify a tetraoxane-based drug candidate that shows no cross-resistance with an artemisinin-resistant strain (PfK13-C580Y) and is eff
Externí odkaz:
https://doaj.org/article/d0b09995908d4fd1a466aa398f702f2f
Autor:
Christina S. Larkin, Mohamed M. Ezat, Natalie L. Roberts, Henning A. Bauch, Robert F. Spielhagen, Riko Noormets, Leonid Polyak, Steven G. Moreton, Tine L. Rasmussen, Michael Sarnthein, Edward T. Tipper, Alex M. Piotrowski
The Nordic Seas are the primary location where the warm waters of the North Atlantic Current densify to form North Atlantic Deep Water, which plays a key part in the modern Atlantic Meridional Overturning Circulation. The formation of dense water in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c9d13e85af89766b985d610eb140be
https://hdl.handle.net/10037/27802
https://hdl.handle.net/10037/27802
Autor:
Gareth S. A. Wright, S. Samar Hasnain, Gina Washbourn, Kangsa Amporndanai, Paul M. O'Neill, Munazza Shahid, Michael Rogers, Varunya Chantadul, Natalie L. Roberts, Svetlana V. Antonyuk, Matthew Pye
Publikováno v:
Communications Biology
COMMUNICATIONS BIOLOGY
Communications Biology, Vol 3, Iss 1, Pp 1-10 (2020)
COMMUNICATIONS BIOLOGY
Communications Biology, Vol 3, Iss 1, Pp 1-10 (2020)
Mutations to the gene encoding superoxide dismutase-1 (SOD1) were the first genetic elements discovered that cause motor neuron disease (MND). These mutations result in compromised SOD1 dimer stability, with one of the severest and most common mutati
Autor:
Sunil Sabbani, Jill Davies, Paul McGillan, Paul O´Neill, Ben Murphy, Richard Amewu, Matthew J. Schnaderbeck, Christopher Riley, Gemma L. Nixon, Emma R. Shore, Stephen A. Ward, Natalie L. Roberts
Publikováno v:
TETRAHEDRON
An efficient route to the synthesis of potent antimalarial aryloxy 1,2,4,5-tetraoxanes is described that permits parallel synthesis for Structure–Activity Relationship (SAR) investigations. Brief details of the in vitro and in vivo antimalarial eva
Autor:
Jerry F. McManus, L. G. Henry, William B Curry, Natalie L Roberts, Alexander M Piotrowski, Lloyd D Keigwin
Publikováno v:
Science. 353:470-474
An ocean of climate impacts Large decreases in Atlantic meridional overturning circulation accompanied every one of the cold Northern Hemispheric stadial events that occurred during the heart of the last glacial period. These events, lasting on avera
Publikováno v:
Paleoceanography. 29:668-679
Over the last 2 decades, significant advances have been made in reconstructing past rates of ocean circulation using sedimentary proxies for the dynamics of abyssal waters. In this study we combine the use of two rate proxies, sortable silt grain siz
Autor:
Albert Galy, Natalie L Roberts, Josephine A. Clegg, Jimin Yu, David J. Wilson, J. A. L. Nicholl, Alexander M Piotrowski
Publikováno v:
Earth and Planetary Science Letters. :289-297
During the last few decades, neodymium isotopes have been increasingly used as a paleoceanographic and paleoclimate proxy on million-year through millennial time-scales. The widespread use of the Nd isotope proxy depends on whether the Nd isotopic co
Autor:
Timothy I. Eglinton, Natalie L Roberts, Alexander M Piotrowski, Henry Elderfield, Michael W. Lomas
Publikováno v:
Geochimica et Cosmochimica Acta
Neodymium isotopes are becoming widely used as a palaeoceanographic tool for reconstructing the source and flow direction of water masses. A new method using planktonic foraminifera which have not been chemically cleaned has proven to be a promising
Autor:
R. E. M. Rickaby, Natalie L Roberts, Henry Elderfield, Andreas Mackensen, Claus-Dieter Hillenbrand
Publikováno v:
Paleoceanography. 25
An increase in whole ocean alkalinity during glacial periods could account, in part, for the drawdown of atmospheric CO2 into the ocean. Such an increase was inevitable due to the near elimination of shelf area for the burial of coral reef alkalinity
Publikováno v:
Science (New York, N.Y.). 327(5961)
The Depths of the Changes Over the course of the past glacial cycle, there have been two major types of rapid, large climate warming events: shorter-lived warm intervals lasting on the order of 1000 years and the last glacial-interglacial transition.