Výsledky vyhledávání - "Natalie L. Prigozhina"

Akademický článek

Detection and Characterization of Circulating Tumour Cells in Multiple Myeloma

Autor: Liangxuan Zhang, Sharon Beasley, Natalie L. Prigozhina, Renee Higgins, Shoji Ikeda, Florence Y. Lee, Dena Marrinucci, Shidong Jia

Publikováno v: Journal of Circulating Biomarkers, Vol 5 (2016)

Multiple myeloma (MM) remains an incurable disease despite recent therapeutic improvements. The ability to detect and characterize MM circulating tumour cells (CTCs) in peripheral blood provides an alternative to replace or augment invasive bone marr

Externí odkaz: https://doaj.org/article/1ecf56b374cb416ebbba2bb152c35a37

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Assay of Calcium Transients and Synapses in Rat Hippocampal Neurons by Kinetic Image Cytometry and High-Content Analysis: An In Vitro Model System for Postchemotherapy Cognitive Impairment

Autor: Ranor C.B. Basa, Patrick M. McDonough, Natalie L Prigozhina, Jeffrey H. Price

Publikováno v: ASSAY and Drug Development Technologies. 15:220-236

Postchemotherapy cognitive impairment (PCCI) is commonly exhibited by cancer patients treated with a variety of chemotherapeutic agents, including the endocrine disruptor tamoxifen (TAM). The etiology of PCCI is poorly understood. Our goal was to dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c858775f6864b09a9d53d0fb9b4a415d
https://doi.org/10.1089/adt.2017.797

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Amphiphilic suramin dissolves Matrigel, causing an ‘inhibition’ artefact withinin vitroangiogenesis assays

Autor: Natalie L. Prigozhina, Nicholas D. P. Cosford, Andrew J. Heisel, Jeffrey H. Price, Jordan R. Seldeen

Publikováno v: International Journal of Experimental Pathology. 94:412-417

The field of study concerning promotion and/or inhibition of angiogenesis has gathered much attention in the scientific community. A great deal of work has been invested towards defining reproducible assays to gauge for promotion or inhibition of ang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da832903ddb243d23e0d6b57dfb761c4
https://doi.org/10.1111/iep.12043

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Detection and Characterization of Circulating Tumour Cells in Multiple Myeloma

Autor: Shoji Ikeda, Florence Y. Lee, Dena Marrinucci, Liangxuan Zhang, Natalie L. Prigozhina, Shidong Jia, Reneé Higgins, Sharon Beasley

Publikováno v: Journal of Circulating Biomarkers, Vol 5 (2016)
Journal of Circulating Biomarkers
Volume 5
Issue Godište 2016
Journal of Circulating Biomarkers, Vol 5, Iss, p 10 (2016)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb6e00b30b2e29e73a842dec0de269e
https://doaj.org/article/1ecf56b374cb416ebbba2bb152c35a37

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Characterization of a novel angiogenic model based on stable, fluorescently labelled endothelial cell lines amenable to scale-up for high content screening

Autor: Diego Calzolari, Andrew J. Heisel, Pilar Ruiz-Lozano, Jeffrey H. Price, Mark Mercola, Elena B. Pasquale, Jordan R. Seldeen, Edward A. Hunter, Natalie L. Prigozhina, Roberta Noberini, Ke Wei

Publikováno v: Biology of the Cell. 103:467-481

Background. Blood vessel formation is important for many physiological and pathological processes and is therefore a critical target for drug development. Inhibiting angiogenesis to starve a tumour or promoting ‘normalization’ of tumour vasculatu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bec7a9128afbd9374e92ea68fe97e54
https://doi.org/10.1042/bc20100146

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Plasma Membrane Assays And Three-Compartment Image Cytometry for High Content Screening

Autor: Michael A. Mancini, Ling Zhong, Dennis R. Roop, Edward A. Hunter, Jeffrey H. Price, Patrick M. McDonough, David A. Zacharias, Natalie L. Prigozhina, Scott Callaway, I. Mikic

Publikováno v: ASSAY and Drug Development Technologies. 5:29-48

High throughput image cytometers analyze individual cells in digital photomicrographs by first assigning pixels within each image to plasma membrane, cytoplasm, nucleus, or other regions. In this study, we report on a novel algorithm that: 1) identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4223e621dab565653ba016c2cc6ef74
https://doi.org/10.1089/adt.2006.024

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Protein-tyrosine Pseudokinase 7 (PTK7) Directs Cancer Cell Motility and Metastasis*

Autor: Natalie L. Prigozhina, John D. Lewis, Phillip E. Schwartz, Robert M. Hoffman, Alex Y. Strongin, Konstantin Stoletov, Vladislav S. Golubkov, Yong Zhang

It is well established that widely expressed PTK7 is essential for vertebrate tissue morphogenesis. In cancer, the functionality of PTK7 is selectively regulated by membrane type-1 matrix metalloproteinase (MT1-MMP), ADAMs (a disintegrin domain and m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1eb06c072f721e3435c5f13d30af7d9
https://europepmc.org/articles/PMC4148854/

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Quantification of lipid droplets and associated proteins in cellular models of obesity via high-content/high-throughput microscopy and automated image analysis

Autor: Patricia A. Loy, Jeffrey H. Price, Patrick M. McDonough, Randall S. Ingermanson, Ramses M. Agustin, Natalie L. Prigozhina, Benjamin M. Buehrer, I. Mikic, James B. Nicoll

Publikováno v: Assay and drug development technologies. 7(5)

Intracellular lipid droplets are associated with a myriad of afflictions including obesity, fatty liver disease, coronary artery disease, and infectious diseases (eg, HCV and tuberculosis). To develop high-content analysis (HCA) techniques to analyze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19998d998550af577846e37397ca05a3
https://pubmed.ncbi.nlm.nih.gov/19895345

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Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes

Autor: Nathan Salomonis, Karen Wei, Brandon Nelson, Ruchi Bajpai, Diego Calzolari, Jeffrey H. Price, Maria Barcova, Natalie L. Prigozhina, Alexey V. Terskikh, René Haverslag, Changsung Kim, H. S. Vincent Chen, Andrew D. McCulloch, Jeffrey G. Jacot, Sean Spiering, Maria Talantova, Hiroko Kita-Matsuo, Bruce R. Conklin, Mark Mercola

Publikováno v: PloS one, vol 4, iss 4
Kita-Matsuo, H; Barcova, M; Prigozhina, N; Salomonis, N; Wei, K; Jacot, JG; et al.(2009). Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS ONE, 4(4). doi: 10.1371/journal.pone.0005046. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6w7867ds
PLoS ONE, Vol 4, Iss 4, p e5046 (2009)
PLoS ONE

Author(s): Kita-Matsuo, Hiroko; Barcova, Maria; Prigozhina, Natalie; Salomonis, Nathan; Wei, Karen; Jacot, Jeffrey G; Nelson, Brandon; Spiering, Sean; Haverslag, Rene; Kim, Changsung; Talantova, Maria; Bajpai, Ruchi; Calzolari, Diego; Terskikh, Alexe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d48739c4b0593532f439562282b341
https://escholarship.org/uc/item/6w7867ds

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Decreased polarity and increased random motility in PtK1 epithelial cells correlate with inhibition of endosomal recycling

Autor: Natalie L. Prigozhina, Clare M. Waterman-Storer

Publikováno v: Journal of cell science. 119(Pt 17)

Locomoting cells exhibit a constant retrograde flow of plasma membrane proteins from the leading edge towards the cell center, which, when coupled to substrate adhesion, may drive forward cell movement. Here, we aimed to test the hypothesis that, in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab4cfe68fd0ea09bc0c8ba0111a2fe0
https://pubmed.ncbi.nlm.nih.gov/16931597

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