Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Natalie K. Brown"'
Autor:
Xi Wang, Natalie K. Brown, Bo Wang, Kaavian Shariati, Kai Wang, Stephanie Fuchs, Juan M. Melero‐Martin, Minglin Ma
Publikováno v:
Advanced Science, Vol 8, Iss 17, Pp n/a-n/a (2021)
Abstract Islet transplantation has shown promise as a curative therapy for type 1 diabetes (T1D). However, the side effects of systemic immunosuppression and limited long‐term viability of engrafted islets, together with the scarcity of donor organ
Externí odkaz:
https://doaj.org/article/1603645c79574028a81a6154a978c547
Autor:
DARIO F. DE JESUS, ZIJIE ZHANG, NATALIE K. BROWN, GIORGIO BASILE, LING XIAO, SEVIM KAHRAMAN, CLAYTON E. MATHEWS, ALVIN C. POWERS, MARK A. ATKINSON, DECIO L. EIZIRIK, ROHIT KULKARNI
Publikováno v:
Diabetes. 71
Innate immunity is directly associated with Type 1 diabetes (T1D) . Recently, N6-methyladenosine (m6A) has been shown to modulate human β-cell biology and innate immunity. Here, we focused on the contribution of m6A in modulating T1D development. RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e1ab4c4e16b67860b6673728d7b1e6
https://doi.org/10.2337/db22-9-or
https://doi.org/10.2337/db22-9-or
Autor:
Ercument Dirice, Jiang Hu, Amélia M. Silva, Natalie K. Brown, Larissa Haertle, Dorota Kaminska, Thomas Haaf, Chih-Hao Wang, Tomohiko Kimura, Rohit N. Kulkarni, Ville Männistö, Dario F. De Jesus, Renzo Riemens, Yu-Hua Tseng, Kazuki Orime, Jussi Pihlajamäki, Giorgio Basile
Publikováno v:
J Clin Invest
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Although gene-environment interactions have been implicated in the etiology of several disorders, the impact of paternal and/or maternal metabolic syndrome on the cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4546b532dbcd501a461194f9900067a4
https://doi.org/10.1172/jci127502
https://doi.org/10.1172/jci127502
Autor:
Stephanie Fuchs, Minglin Ma, Kai Wang, Juan M. Melero-Martin, Bo Wang, Kaavian Shariati, Natalie K. Brown, Xi Wang
Publikováno v:
Advanced Science, Vol 8, Iss 17, Pp n/a-n/a (2021)
Advanced Science
Advanced Science
Islet transplantation has shown promise as a curative therapy for type 1 diabetes (T1D). However, the side effects of systemic immunosuppression and limited long‐term viability of engrafted islets, together with the scarcity of donor organs, highli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b31bb414f5550c0e11f9541a24a2cf
https://doaj.org/article/1603645c79574028a81a6154a978c547
https://doaj.org/article/1603645c79574028a81a6154a978c547
Autor:
Rohit N. Kulkarni, Jiang Hu, Chuan He, Mengjie Chen, Manoj K. Gupta, Dario F. De Jesus, Zijie Zhang, Sevim Kahraman, Natalie K. Brown
Publikováno v:
Nature Metabolism. 1:765-774
The regulation of islet cell biology is critical for glucose homeostasis1.N6 -methyladenosine (m6A) is the most abundant internal messenger RNA (mRNA) modification in mammals2. Here we report that the m6A landscape segregates human type 2 diabetes (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f95d72738f5af5de8da37100f626c4f
https://doi.org/10.1038/s42255-019-0089-9
https://doi.org/10.1038/s42255-019-0089-9
Autor:
Dario F. De Jesus, Sevim Kahraman, Clayton E. Mathews, Mark A. Atkinson, Natalie K. Brown, Decio L. Eizirik, Alvin C. Powers, Rohit N. Kulkarni, Zijie Zhang, Chuan He, Jiang Hu
Publikováno v:
Diabetes. 70
Type 1 diabetes (T1D) is an autoimmune disease characterized by a progressive destruction of β-cells and several candidate genes associated with T1D have been linked to innate immunity. Recently, N6-methyladenosine (m6A) has been shown to modulate h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2314f01ee897cce67e9f666f40323839
https://doi.org/10.2337/db21-287-or
https://doi.org/10.2337/db21-287-or
Autor:
Natalie K. Brown
Publikováno v:
Nature.
Natalie Brown explains how her father’s childhood diagnosis has inspired her to research the condition as an undergraduate. Natalie Brown explains how her father’s childhood diagnosis has inspired her to research the condition as an undergraduate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12c51547590c59e03740d8d3b0ac97ec
https://doi.org/10.1038/d41586-020-00225-y
https://doi.org/10.1038/d41586-020-00225-y
Autor:
Dario F, De Jesus, Zijie, Zhang, Sevim, Kahraman, Natalie K, Brown, Mengjie, Chen, Jiang, Hu, Manoj K, Gupta, Chuan, He, Rohit N, Kulkarni
Publikováno v:
Nature metabolism
The regulation of islet cell biology is critical for glucose homeostasis1.N6-methyladenosine (m6A) is the most abundant internal messenger RNA (mRNA) modification in mammals2. Here we report that the m6A landscape segregates human type 2 diabetes (T2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61f6ac93694c59cbfd249d2e219e4d3d
https://pubmed.ncbi.nlm.nih.gov/31867565
https://pubmed.ncbi.nlm.nih.gov/31867565