Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Natalie J. Török"'
Autor:
Yuan Li, Joy X. Jiang, Weiguo Fan, Sarah R. Fish, Suvarthi Das, Parul Gupta, Gergely Mozes, Lorand Vancza, Sutapa Sarkar, Koshi Kunimoto, Dongning Chen, Hyesuk Park, Dahn Clemens, Alexey Tomilov, Gino Cortopassi, Natalie J. Török
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 1, Pp 197-211 (2023)
Background & Aims: Src homology and collagen (Shc) proteins are major adapters to extracellular signals, however, the regulatory role of Shc isoforms in sterile inflammatory responses in alcoholic hepatitis (AH) has not been fully investigated. We hy
Externí odkaz:
https://doaj.org/article/491df578ef6a4f948fce48a5bdc6e425
Autor:
Natalie J. Török, MD
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 3, Pp 299-300 (2017)
Externí odkaz:
https://doaj.org/article/324c915c47bc4877997e54d3cc7ce7fd
Publikováno v:
Journal of Cellular and Molecular Medicine. 27:471-481
Autor:
Bruce D. Hammock, A. F. S. Mello, Natalie J. Török, Fawaz G. Haj, Jun Yang, Ming-Fo Hsu, Bryan Chu, Christophe Morisseau, Jeff Cheng, Shinichiro Koike
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 815-830 (2021)
Cellular and molecular gastroenterology and hepatology, vol 11, iss 3
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 11, iss 3
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Alcohol-associated liver disease (ALD) is a significant cause of liver-related morbidity and mortality worldwide and with limited therapies. Soluble epoxide hydrolase (sEH; Ephx2) is a largely cytosolic enzyme that is highly express
Autor:
Gregory W. Charville, Gergely Mozes, Weiguo Fan, Gino A Cortopassi, Alexey Tomilov, Natalie J. Török, Jon J. Ramsey, David D. Gae, Yuan Li, Sarah R. Fish, Joy X. Jiang, Suvarthi Das, Ali Dehnad
Publikováno v:
Hepatology
Background and aims Older patients with obesity/type II diabetes mellitus frequently present with advanced NASH. Whether this is due to specific molecular pathways that accelerate fibrosis during aging is unknown. Activation of the Src homology 2 dom
Autor:
Weiguo Fan, Natalie J. Török
Publikováno v:
Hepatology Communications, Vol 5, Iss 4, Pp 553-555 (2021)
This is an editorial about non-invasive fibrosis markers in patients with NASH and type 2 diabetes mellitus.
Autor:
Yuan Li, Joy X. Jiang, Weiguo Fan, Sarah R. Fish, Suvarthi Das, Parul Gupta, Gergely Mozes, Lorand Vancza, Sutapa Sarkar, Koshi Kunimoto, Dongning Chen, Hyesuk Park, Dahn Clemens, Alexey Tomilov, Gino Cortopassi, Natalie J. Török
Publikováno v:
Cellular and molecular gastroenterology and hepatology, vol 15, iss 1
Background & aimsSrc homology and collagen (Shc) proteins are major adapters to extracellular signals, however, the regulatory role of Shc isoforms in sterile inflammatory responses in alcoholic hepatitis (AH) has not been fully investigated. We hypo
Autor:
Chun Kui Hui, Claire Montgomery, Joy X. Jiang, Alexey Tomilov, Gino A Cortopassi, Natalie J. Török
Publikováno v:
J Biochem Mol Toxicol
Shc expression rises in human nonalcoholic steatohepatitis (NASH) livers, and Shc-deficient mice are protected from NASH–thus Shc inhibition could be a novel therapeutic strategy for NASH. Idebenone was recently identified as the first small-molecu
Autor:
Xinshou Ouyang, Yanqin Qin, Yonglin Chen, Yasuko Iwakiri, Natalie J. Török, Joy X. Jiang, Suyavaran Arumugam, Muhammad N. Yousaf, Sheng Na Han, Peng Zhao, Mohd Salah Mankash, Junbao Liu, Jiansheng Li
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
The cardiac glycoside digoxin was identified as a potent suppressor of pyruvate kinase isoform 2-hypoxia-inducible factor-α (PKM2-HIF-1α) pathway activation in liver injury mouse models via intraperitoneal injection. We have assessed the therapeuti
Autor:
Paul Y. Kwo, Natalie J. Török, Janice Jiang, Robert K. S. Wong, Omar Alshuwaykh, Raymond E. Kim
Publikováno v:
American Journal of Gastroenterology. 116:S557-S558