Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Natalie J. Alexander"'
Autor:
Sally A.I. Knooihuizen, Natalie J. Alexander, Alex Hopke, Nicolas Barros, Adam Viens, Allison Scherer, Natalie J. Atallah, Zeina Dagher, Daniel Irimia, Raymond T. Chung, Michael K. Mansour
Publikováno v:
Hepatology Communications, Vol 5, Iss 3, Pp 502-515 (2021)
Neutrophils are the most abundant white blood cell in the body and are key participants in the defense against fungal infections. Fungal infections occur often in patients with cirrhosis and are associated with increased 30‐day and 90‐day mortali
Externí odkaz:
https://doaj.org/article/472aa4a3961e474baefe5b88567911b9
Autor:
Natalie J. Atallah, Allison K. Scherer, Natalie J. Alexander, Zeina Dagher, Adam L. Viens, Maged Muhammed, John A. Branda, Michael K. Mansour
Publikováno v:
Medical Mycology Case Reports, Vol 28, Iss , Pp 39-41 (2020)
Necrotizing fasciitis is a potentially fatal soft tissue infection that requires prompt clinical suspicion, pharmacological and surgical interventions. Bacterial pathogens, such as beta-hemolytic streptococcus and Staphylococcus aureus, are the main
Externí odkaz:
https://doaj.org/article/9afd5b78de724d2da1dcae64cbc09cac
Autor:
Paige E. Negoro, Shuying Xu, Zeina Dagher, Alex Hopke, Jennifer L. Reedy, Michael B. Feldman, Nida S. Khan, Adam L. Viens, Natalie J. Alexander, Natalie J. Atallah, Allison K. Scherer, Richard A. Dutko, Jane Jeffery, John F. Kernien, J. Scott Fites, Jeniel E. Nett, Bruce S. Klein, Jatin M. Vyas, Daniel Irimia, David B. Sykes, Michael K. Mansour
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Invasive fungal infections constitute a lethal threat, with patient mortality as high as 90%. The incidence of invasive fungal infections is increasing, especially in the setting of patients receiving immunomodulatory agents, chemotherapy, o
Externí odkaz:
https://doaj.org/article/8ea9d37e9ee144ada176ccd4590e9d2d
Autor:
Adam L. Viens, Kyle D. Timmer, Natalie J. Alexander, Rana Barghout, Jelena Milosevic, Alex Hopke, Natalie J. Atallah, Allison K. Scherer, David B. Sykes, Daniel Irimia, Michael K. Mansour
Publikováno v:
The Journal of Immunology. 208:1664-1674
An impaired neutrophil response to pathogenic fungi puts patients at risk for fungal infections with a high risk of morbidity and mortality. Acquired neutrophil dysfunction in the setting of iatrogenic immune modulators can include the inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24271ea807bf3381f801818774d63f61
https://doi.org/10.4049/jimmunol.2100599
https://doi.org/10.4049/jimmunol.2100599
Autor:
Allison K. Scherer, Alex Hopke, Shuying Xu, Adam Viens, Natalie J. Alexander, Kyle D. Timmer, Dakota Archambault, Daniel Floyd, Natalie J. Atallah, Catherine Rhee, Murat Cetinbas, David T. Scadden, Daniel Irimia, David B. Sykes, Ruslan I. Sadreyev, Michael K. Mansour
Once perceived to be homogenous effector cells, neutrophils have since been shown to exhibit population heterogeneity. Here, we established an experimental model of clonal neutrophil heterogeneity using conditionally immortalized clonal granulocyte m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b33aa3cb16e20712865b8a692d40777
https://doi.org/10.1101/2022.11.01.514676
https://doi.org/10.1101/2022.11.01.514676
Autor:
Kyle Timmer, Natalie J. Alexander, Michael K. Mansour, Daniel Irimia, Nicolas Barros, Alex Hopke, Allison K. Scherer, Zeina Dagher, Adam Viens, Sally A.I. Knooihuizen, Natalie J. Atallah
Publikováno v:
J Infect Dis
Background Solid organ transplant (SOT) and stem cell transplant (SCT) recipients are at increased risk of invasive fungal disease despite normal neutrophil counts. Here, we measure neutrophil anti-Candida activity. Methods Twenty-one SOT and 19 SCT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d9255a41bd505b86c027baf5e5c326
https://doi.org/10.1093/infdis/jiab009
https://doi.org/10.1093/infdis/jiab009
Autor:
Daniel Irimia, Nicolas Barros, Allison K. Scherer, Raymond T. Chung, Adam Viens, Natalie J. Alexander, Michael K. Mansour, Natalie J. Atallah, Zeina Dagher, Alex Hopke, Sally A.I. Knooihuizen
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 5, Iss 3, Pp 502-515 (2021)
Hepatology Communications, Vol 5, Iss 3, Pp 502-515 (2021)
Neutrophils are the most abundant white blood cell in the body and are key participants in the defense against fungal infections. Fungal infections occur often in patients with cirrhosis and are associated with increased 30‐day and 90‐day mortali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80505c0bfdf7e5ae4c8b522611ae519b
http://europepmc.org/articles/PMC7917271
http://europepmc.org/articles/PMC7917271
Autor:
David B Sykes, Michelle M Martinelli, Paige Negoro, Shuying Xu, Katrina Maxcy, Kyle Timmer, Adam L Viens, Natalie J Alexander, Johnny Atallah, Brendan D Snarr, Shane R Baistrocchi, Natalie J Atallah, Alex Hopke, Allison Scherer, Ivy Rosales, Daniel Irimia, Donald C Sheppard, Michael K Mansour
Publikováno v:
Journal of leukocyte biology. 111(6)
The use of mature neutrophil (granulocyte) transfusions for the treatment of neutropenic patients with invasive fungal infections (IFIs) has been the focus of multiple clinical trials. Despite these efforts, the transfusion of mature neutrophils has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bf3d12b0b286ea3a41a4b770799ebd
https://pubmed.ncbi.nlm.nih.gov/35362111
https://pubmed.ncbi.nlm.nih.gov/35362111
Autor:
Zeina Dagher, Adam Viens, Allison K. Scherer, Michael K. Mansour, Natalie J. Atallah, John A. Branda, Natalie J. Alexander, Maged Muhammed
Publikováno v:
Medical Mycology Case Reports
Medical Mycology Case Reports, Vol 28, Iss, Pp 39-41 (2020)
Medical Mycology Case Reports, Vol 28, Iss, Pp 39-41 (2020)
Necrotizing fasciitis is a potentially fatal soft tissue infection that requires prompt clinical suspicion, pharmacological and surgical interventions. Bacterial pathogens, such as beta-hemolytic streptococcus and Staphylococcus aureus, are the main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45db00bf32086d4fe2ade66df9a2c227
https://doi.org/10.1016/j.mmcr.2020.04.004
https://doi.org/10.1016/j.mmcr.2020.04.004
Autor:
John F. Kernien, Michael Feldman, Shuying Xu, Paige E. Negoro, Allison K. Scherer, Alex Hopke, Jennifer L. Reedy, Jeniel E. Nett, Daniel Irimia, Natalie J. Alexander, J. Scott Fites, Nida S. Khan, Michael K. Mansour, Zeina Dagher, Richard A. Dutko, Jatin M. Vyas, Natalie J. Atallah, Bruce S. Klein, Adam Viens, David B. Sykes, Jane B Jeffery
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
mBio, Vol 11, Iss 3, p e02043-19 (2020)
mBio, Vol 11, Iss 3, p e02043-19 (2020)
Invasive fungal infections constitute a lethal threat, with patient mortality as high as 90%. The incidence of invasive fungal infections is increasing, especially in the setting of patients receiving immunomodulatory agents, chemotherapy, or immunos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16557bea15c0fec40fed9416f529256
https://journals.asm.org/doi/10.1128/mBio.02043-19
https://journals.asm.org/doi/10.1128/mBio.02043-19