Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Natalie J. Hannan"'
Autor:
Lucy A. Bartho, Daniel R. McKeating, Susan P. Walker, Brunda Nijagal, Teresa M. MacDonald, Natasha Pritchard, Natalie J. Hannan, Anthony V. Perkins, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metabolomics is the study of small molecules (metabolites), within cells, tissues and biofluids. Maternal metabolites can provide important insight into the health and development of both mother and fetus throughout pregnancy. This study ass
Externí odkaz:
https://doaj.org/article/f38eb2cd176049bfb44b36cc0ecad250
Autor:
Lydia Baird, Ping Cannon, Manju Kandel, Tuong-Vi Nguyen, Anna Nguyen, Georgia Wong, Cíara Murphy, Fiona C. Brownfoot, Elif Kadife, Natalie J. Hannan, Stephen Tong, Lucy A. Bartho, Tu’uhevaha J. Kaitu’u-Lino
Publikováno v:
Reproductive Biology and Endocrinology, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Preeclampsia is a severe complication of pregnancy which is attributed to placental dysfunction. The retrotransposon, Paternal Expressed Gene 10 (PEG10) harbours critical placental functions pertaining to placental trophoblast cel
Externí odkaz:
https://doaj.org/article/139c5e16fdb548e5b92b05ec1676dcad
Autor:
Bridget M. Arman, Natalie K. Binder, Natasha de Alwis, Sally Beard, Danielle A. Debruin, Alan Hayes, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino, Natalie J. Hannan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Spontaneous preterm birth is the leading cause of perinatal morbidity and mortality. Tocolytics are drugs used in cases of imminent preterm birth to inhibit uterine contractions. Nifedipine is a calcium channel blocking agent used to delay t
Externí odkaz:
https://doaj.org/article/ecae7aa9492148a588dc9ec772536a2e
Autor:
Bianca R. Fato, Sally Beard, Natalie K. Binder, Natasha Pritchard, Tu’uhevaha J. Kaitu’u-Lino, Natasha de Alwis, Natalie J. Hannan
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2660 (2023)
Gestational diabetes mellitus (GDM) is a condition of pregnancy defined by new-onset hyperglycemia. GDM is associated with impaired maternal endothelial and vascular reactivity. Endothelin-1 (ET-1) is a potent vasoconstrictor that contributes to endo
Externí odkaz:
https://doaj.org/article/c4d4ec67fad0462a9d66aeeffb7c39f9
Autor:
Natasha de Alwis, Sally Beard, Natalie K. Binder, Natasha Pritchard, Tu’uhevaha J. Kaitu’u-Lino, Susan P. Walker, Owen Stock, Katie M. Groom, Scott Petersen, Amanda Henry, Joanne M. Said, Sean Seeho, Stefan C. Kane, Stephen Tong, Natalie J. Hannan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) transcripts are elevated in the circulation of individuals whose pregnancies are complicated by preterm fetal growth restriction (FGR). In this paper, we show that the cases with preeclam
Externí odkaz:
https://doaj.org/article/fd7a986eec1140abaec2740950069538
Autor:
Manju Kandel, Stephen Tong, Susan P Walker, Ping Cannon, Tuong-Vi Nguyen, Teresa M. MacDonald, Natalie J. Hannan, Tu’uhevaha J. Kaitu’u-Lino, Lucy A Bartho
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Preeclampsia is a disease of pregnancy responsible for significant maternal and neonatal mortality. Galectin-3 is a β-Galactoside binding protein. This study aimed to characterise galectin-3 in women with preeclampsia and human trophoblast stem cell
Externí odkaz:
https://doaj.org/article/6ae85dac2026490296b52890bce0f9ab
Autor:
Damanpreet Garcha, Susan P. Walker, Teresa M. MacDonald, Jon Hyett, Jessica Jellins, Jenny Myers, Sebastian E. Illanes, Jhy K. Nien, Manuel Schepeler, Emerson Keenan, Carole-Anne Whigham, Ping Cannon, Elizabeth Murray, Tuong-Vi Nguyen, Manju Kandel, Joshua Masci, Ciara Murphy, Tess Cruickshank, Natasha Pritchard, Natalie J. Hannan, Fiona Brownfoot, Alexandra Roddy Mitchell, Anna Middleton, Gabrielle Pell, Georgia P. Wong, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Fetal growth restriction is a leading cause of stillbirth that often remains undetected during pregnancy. Identifying novel biomarkers may improve detection of pregnancies at risk. This study aimed to assess syndecan-1 as a biomarker for sma
Externí odkaz:
https://doaj.org/article/b9a4aa52db5d4a63b2d39175244dc8af
Autor:
Roxanne Hastie, Lina Bergman, Susan P. Walker, Tu'uhevaha Kaitu'u‐Lino, Natalie J. Hannan, Fiona Brownfoot, Sonja Schell, Alesia Harper, Ping Cannon, Catherine A. Cluver, Stephen Tong
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 16 (2022)
Background The angiogenic factors soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and placental growth factor (PlGF) are postulated to be pathogenic disease drivers of preeclampsia. If true, then circulating levels should become more deranged with
Externí odkaz:
https://doaj.org/article/ce31eed7eed84510833ab10efcf561d1
Autor:
Natasha de Alwis, Sally Beard, Natalie K. Binder, Natasha Pritchard, Tu’uhevaha J. Kaitu’u-Lino, Susan P. Walker, Owen Stock, Katie Groom, Scott Petersen, Amanda Henry, Joanne M. Said, Sean Seeho, Stefan C. Kane, Lisa Hui, Stephen Tong, Natalie J. Hannan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Previously, we identified increased maternal circulating DAAM2 mRNA in pregnancies complicated by preterm fetal growth restriction (FGR). Here, we assessed whether circulating DAAM2 mRNA could detect FGR, and whether the DAAM2 gene, known to
Externí odkaz:
https://doaj.org/article/651f19d9ebf742ba844ba2da24a85f7f
Autor:
Natalie K. Binder, Sally Beard, Natasha de Alwis, Bianca R. Fato, Tuong-Vi Nguyen, Tu’uhevaha J. Kaitu’u-Lino, Natalie J. Hannan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6182 (2023)
Preeclampsia is associated with an increased lifelong risk of cardiovascular disease (CVD). It is not clear whether this is induced by persistent systemic organ and vascular damage following preeclampsia or due to a predisposition to both conditions
Externí odkaz:
https://doaj.org/article/2a303682986d41c091fe5fe2038086cb