Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Natalie J Thompson"'
Autor:
Saurabh K Srivastava, Vincent J B Ruigrok, Natalie J Thompson, Anke K Trilling, Albert J R Heck, Cees van Rijn, Jules Beekwilder, Maarten A Jongsma
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64040 (2013)
BACKGROUND: The 16 kDa heat shock protein (HSP) is an immuno-dominant antigen, used in diagnosis of infectious Mycobacterium tuberculosis (M.tb.) causing tuberculosis (TB). Its use in serum-based diagnostics is limited, but for the direct identificat
Externí odkaz:
https://doaj.org/article/0dd5c70f4a6f4ba59ec4c6a630ed4c8a
Publikováno v:
TrAC Trends in Analytical Chemistry. 48:72-80
Mass spectrometry (MS) is emerging as an efficient method for the structural analysis of various new antibody-based therapeutic products. Here, we review the current trends and describe recent applications that highlight the use of MS to tackle the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::263ea614f11f20d55ed398a4e01efc45
https://doi.org/10.1016/j.trac.2013.02.013
https://doi.org/10.1016/j.trac.2013.02.013
Autor:
Alexander Makarov, Albert J. R. Heck, Esther van Duijn, Eugen Damoc, Rebecca J. Rose, Sara Rosati, Eduard Denisov, Natalie J. Thompson
Publikováno v:
Angewandte Chemie. 124:13166-13170
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5dcbbaeb9204a3ec94b36bc63896e9d
https://doi.org/10.1002/ange.201206745
https://doi.org/10.1002/ange.201206745
Autor:
Eduard Denisov, Rebecca J. Rose, Alexander Makarov, Esther van Duijn, Eugen Damoc, Natalie J. Thompson, Sara Rosati, Albert J. R. Heck
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition; Vol 51
Angewandte Chemie International Edition; Vol 51
Monoclonal antibodies (mAbs) represent a major class of therapeutic biomolecules being developed by the biopharmaceutical industry, their popularity largely being a result of their high specificity towards targets. Therapeutic mAbs are being develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3e22764891f4affc88e5975e85f527
Autor:
Thomas Kislinger, Ruth Isserlin, Maria G. Trivieri, Anthony O. Gramolini, David H. MacLennan, Natalie J. Thompson, Andrew Emili, Brendan J. Frey, Ailis Fagan, Hendrik Huedig, Gavin Y. Oudit, Peter P. Liu, Anitha Kannan, Jonathan G. Seidman, Vincent Fong, Peter H. Backx, Sara Arab, Rasoul Alikhani-Koopaei, George Hess, Parveen Sharma, Marc D. Perry, Desmond G. Higgins, Christine E. Seidman
Publikováno v:
Molecular & Cellular Proteomics. 7:519-533
Defective mobilization of Ca2+ by cardiomyocytes can lead to cardiac insufficiency, but the causative mechanisms leading to congestive heart failure (HF) remain unclear. In the present study we performed exhaustive global proteomics surveys of cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b610aa58cc884ed8160fca5e461843
https://doi.org/10.1074/mcp.m700245-mcp200
https://doi.org/10.1074/mcp.m700245-mcp200
Autor:
Natalie J. Thompson, Jean-Luc Brédas, Kelly Lancaster, Veaceslav Coropceanu, Seth R. Marder, Stephen Barlow, Kelly M. Lefler, Luca Beverina, Susan A. Odom
Publikováno v:
Chemistry - A European Journal. 13:9637-9646
Five diamines with thiophene-based bridges-(E)-1,2-bis-{5-[bis(4- butoxyphenyl)amino]-2-thienyljethylene (1), 5,5′-bis[bis(4-methoxyphenyl) amino]-2,2′-bithiophene (2), 2,6-bis[bis(4-butoxyphenyl)amino]dithieno[3, 2-b:2′,3′-d]thiophene (3), N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3606d9e81b93345e77a9734429e99513
https://doi.org/10.1002/chem.200700668
https://doi.org/10.1002/chem.200700668
Autor:
Natalie J. Thompson, Jonathan S. Weissman, Sean R. Collins, Andrew Emili, Maya Schuldiner, Thanuja Punna, Kayu Chin, Stephen Buratowski, Timothy P. Hughes, Michael Grunstein, Charles Boone, Nevan J. Krogan, Jack Greenblatt, Michael-Christopher Keogh, Siavash K. Kurdistani, Stephanie A. Morris, Brian D. Strahl, Vladimir Podolny, Seong Hoon Ahn
Publikováno v:
Cell. 123(4):593-605
SummaryThe yeast histone deacetylase Rpd3 can be recruited to promoters to repress transcription initiation. Biochemical, genetic, and gene-expression analyses show that Rpd3 exists in two distinct complexes. The smaller complex, Rpd3C(S), shares Sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553623142937a8ec1463b1d4675231bb
Autor:
Kristin Ingvarsdottir, Andrew Emili, Timothy P. Hughes, Natalie J. Thompson, Shelley L. Berger, Jack Greenblatt, N. C. Tolga Emre, Nevan J. Krogan, Anastasia Wyce
Publikováno v:
Molecular and Cellular Biology. 25:1162-1172
The SAGA complex is a multisubunit protein complex involved in transcriptional regulation in Saccharomyces cerevisiae. SAGA combines proteins involved in interactions with DNA-bound activators and TATA-binding protein (TBP), as well as enzymes for hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2911f2056648188a4dba0df01fa133a
https://doi.org/10.1128/mcb.25.3.1162-1172.2005
https://doi.org/10.1128/mcb.25.3.1162-1172.2005
Autor:
Nira Datta, Michael-Christopher Keogh, Natalie J. Thompson, Michael Davey, Nevan J. Krogan, Andrew Emili, Jeff Pootoolal, Kristin Baetz, Trevor C. Y. Kwok, Philip Hieter, Jack Greenblatt, Stephen Buratowski, Timothy P. Hughes, Chika Sawa
Publikováno v:
Proceedings of the National Academy of Sciences. 101:13513-13518
NuA4, the only essential histone acetyltransferase complex in Saccharomyces cerevisiae , acetylates the N-terminal tails of histones H4 and H2A. Affinity purification of NuA4 revealed the presence of three previously undescribed subunits, Vid21/Eaf1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0136d21d9bd99904bd894d33e7d8f0
https://doi.org/10.1073/pnas.0405753101
https://doi.org/10.1073/pnas.0405753101
Autor:
Alexander Berthold Hendrik Bakker, Linda Johanna Aleida Hendriks, Esther van Duijn, Sara Rosati, John de Kruif, Arjan Barendregt, Natalie J. Thompson, Mark Throsby, Albert J. R. Heck
Publikováno v:
Analytical chemistry. 84(16)
Native mass spectrometry was evaluated for the qualitative and semiquantitative analysis of composite mixtures of antibodies representing biopharmaceutical products coexpressed from single cells. We show that by using automated peak fitting of the io
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a1dbb3308dc345a9bbdab2559a367c
https://pubmed.ncbi.nlm.nih.gov/22882109
https://pubmed.ncbi.nlm.nih.gov/22882109