Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Natalie J Hannan"'
Autor:
Teresa M MacDonald, Susan P Walker, Natalie J Hannan, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103780- (2022)
Summary: Preeclampsia is pregnancy-specific, and significantly contributes to maternal, and perinatal morbidity and mortality worldwide. An effective predictive test for preeclampsia would facilitate early diagnosis, targeted surveillance and timely
Externí odkaz:
https://doaj.org/article/1cf0eba2fffd4463afbde578f21bd073
Autor:
Pathum Thilakasiri, Jennifer Huynh, Ashleigh R Poh, Chin Wee Tan, Tracy L Nero, Kelly Tran, Adam C Parslow, Shoukat Afshar‐Sterle, David Baloyan, Natalie J Hannan, Michael Buchert, Andrew Mark Scott, Michael DW Griffin, Frederic Hollande, Michael W Parker, Tracy L Putoczki, Matthias Ernst, Ashwini L Chand
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 4, Pp n/a-n/a (2019)
Abstract Excessive signaling through gp130, the shared receptor for the interleukin (IL)6 family of cytokines, is a common hallmark in solid malignancies and promotes their progression. Here, we established the in vivo utility of bazedoxifene, a ster
Externí odkaz:
https://doaj.org/article/f3ddb855617e4e378193d6b8beddb2bb
Autor:
Tu'uhevaha J Kaitu'u-Lino, Fiona C Brownfoot, Sally Beard, Ping Cannon, Roxanne Hastie, Tuong V Nguyen, Natalie K Binder, Stephen Tong, Natalie J Hannan
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0188845 (2018)
The discovery of new treatments that prevent or treat preeclampsia would be a major advance. Antiangiogenic factors soluble fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sENG) are secreted in excess from the placenta, causing hypertension
Externí odkaz:
https://doaj.org/article/bfb8090bf31148f6bd84804d7f40e274
Autor:
Natalie J Hannan, Natalie K Binder, Sally Beard, Tuong-Vi Nguyen, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0187082 (2018)
Preeclampsia is one of the most serious complications of pregnancy. Currently there are no medical treatments. Given placental oxidative stress may be an early trigger in the pathogenesis of preeclampsia, therapies that enhance antioxidant pathways h
Externí odkaz:
https://doaj.org/article/c76c1bca21da4a4799aca7d9fbd3b0dc
Autor:
Lucy A. Bartho, Daniel R. McKeating, Susan P. Walker, Brunda Nijagal, Teresa M. MacDonald, Natasha Pritchard, Natalie J. Hannan, Anthony V. Perkins, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metabolomics is the study of small molecules (metabolites), within cells, tissues and biofluids. Maternal metabolites can provide important insight into the health and development of both mother and fetus throughout pregnancy. This study ass
Externí odkaz:
https://doaj.org/article/f38eb2cd176049bfb44b36cc0ecad250
Autor:
Natalie K Binder, Jemma Evans, Lois A Salamonsen, David K Gardner, Tu'uhevaha J Kaitu'u-Lino, Natalie J Hannan
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163096 (2016)
Embryo implantation requires synchronized dialogue between the receptive endometrium and activated blastocyst via locally produced soluble mediators. During the mid-secretory (MS) phase of the menstrual cycle, increased glandular secretion into the u
Externí odkaz:
https://doaj.org/article/7bc92863f861496e92d3fe48ff0f831e
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93320 (2014)
We have previously shown in two independent cohorts that circulating first trimester Macrophage Inhibitory Cytokine-1 (MIC-1) levels are lower in women in early pregnancy who are destined to miscarriage. While promising, the diagnostic performance of
Externí odkaz:
https://doaj.org/article/304be50a245141939ccdb4b73294c867
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53098 (2012)
BACKGROUND: Synchronous development of the endometrium (to achieve a receptive state) and of the embryo is essential for successful implantation and ongoing pregnancy. Endometrial receptivity exists only for a finite time in a menstrual cycle and the
Externí odkaz:
https://doaj.org/article/e59bab97e4624cc48e0cc3ca0e503c01
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52304 (2012)
Worldwide, 48% of adult males are overweight or obese. An association between infertility and excessive body weight is now accepted, although focus remains primarily on females. It has been shown that parental obesity results in compromised embryo de
Externí odkaz:
https://doaj.org/article/8fd2e452be17409bb17119a039ecefe9
Autor:
Natalie K. Binder, Natasha de Alwis, Sally Beard, Elif Kadife, Alesia Harper, Tu'uhevaha J. Kaitu'u-Lino, Fiona C. Brownfoot, Natalie J. Hannan
Publikováno v:
Placenta. 132:20-26