Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Natalie Giles"'
Autor:
ngiles@anhb.uwa.edu.au, Natalie Giles
This thesis presents the results of an investigation into the structural protein, tubulin, as a potential target for anti-trypanosomatid drug discovery and vaccine development. Recombinant alpha- and beta- tubulin proteins from Trypanosoma brucei rho
Autor:
Catherine Boulanger, Susan M. Ray, Amita Gupta, Christopher M. Brown, Natalie Cain, George E. Nelson, Sarah A. Longworth, Natalie Giles, Jyoti S. Mathad, Natasha Chida, Christian Petrauskis, Jane McKenzie-White, Valeria Fabre, Michael T. Melia, Diana Silva Cantillo, Robert C. Bollinger, Marcos C. Schechter, Kelly Carpenter, Paulina A. Rebolledo, Valerianna Amorosa
Publikováno v:
Open Forum Infectious Diseases
BackgroundInternal medicine physicians are often the first providers to encounter patients with a new diagnosis of tuberculosis. Given the public health risks of missed tuberculosis cases, assessing internal medicine residents’ ability to diagnose
Autor:
Richard Maganga, Katharine F. Adcroft, Diane S. Keeney, Natalie Giles, Arunasalam Dharmarajan, Fiona M. Wood, Mark W. Fear, Ambili Unni
Publikováno v:
Biochemical and Biophysical Research Communications. 377:606-611
The skin provides vital protection from infection and dehydration. Maintenance of the skin is through a constant program of proliferation, differentiation and apoptosis of epidermal cells, whereby proliferating cells in the basal layer differentiatin
Autor:
Fiona M. Wood, Lyn Beazley, Adrian K. West, Sian Falder, Natalie Morellini, Natalie Giles, Mark W. Fear, Carolyn E. King, Katharine F. Adcroft, Sarah A. Dunlop, Suzanne Rea
Publikováno v:
Wound Repair and Regeneration. 16:682-690
Severe injury to the epidermal barrier often results in scarring and life-long functional deficits, the outcome worsening with a number of factors including time taken to heal. We have investigated the potential of exogenous metallothionein IIA (Zn7-
Publikováno v:
Stem Cell Research & Therapy
IntroductionThe aim of our study is to identify the contribution of hematopoietic-derived cells to burn-wound healing in a non-severe injury. There are many conflicting reports of the contribution of bone marrow-derived cells to wound healing and whe
Publikováno v:
Clinical Endocrinology. 55:689-693
Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal dominant tumour syndrome. It is characterized by primary hyperparathyroidism, pituitary neoplasia and foregut lineage neuroendocrine neoplasia. Malignant thymic carcinoid tumours are an unco
Publikováno v:
Burns : journal of the International Society for Burn Injuries. 38(1)
Background The use of non-cultured autologous cells to promote wound healing and in reconstructive procedures is increasing. One common method for preparing these cells is the use of the ReCell ® device. However, despite its current clinical use, no
Autor:
Mark W. Fear, Gerard Eddy Poinern, Katharine F. Adcroft, Fiona M. Wood, Natalie Giles, Leigh G. Parkinson
Publikováno v:
Tissue engineering. Part A. 15(12)
Cells respond to changes in the environment by altering their phenotype. The ability to influence cell behavior by modifying their environment provides an opportunity for therapeutic application, for example, to promote faster wound healing in respon
Publikováno v:
Parasitology research. 104(4)
The binding kinetics of five novel trifluralin analogs with recombinant alpha- and beta-tubulin proteins from Trypanosoma brucei rhodesiense was determined. Native tubulin from rats was used to determine the extent of binding of each analog to mammal
Autor:
Steven A R Webb, Suzanne Rea, Mark W. Fear, Fiona M. Wood, Lauren M. Evill, Natalie Giles, Katharine F. Adcroft, Deborah H. Strickland
Publikováno v:
Burns : journal of the International Society for Burn Injuries. 35(3)
Scarring after severe burn is a result of changes in collagen deposition and fibroblast activity that result in repaired but not regenerated tissue. Re-epithelialisation of wounds and dermal cell repopulation has been thought to be driven by cells in