Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Natalie G. Anosova"'
Autor:
Catherine Berry, Vincent Pavot, Natalie G. Anosova, Michael Kishko, Lu Li, Tim Tibbitts, Alice Raillard, Sylviane Gautheron, Sheila Cummings, Dinesh S. Bangari, Swagata Kar, Caroline Atyeo, Yixiang Deng, Galit Alter, Cindy Gutzeit, Marguerite Koutsoukos, Roman M. Chicz, Valerie Lecouturier
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-16 (2023)
Abstract Background Since the beginning of the COVID-19 pandemic, several variants of concern (VOC) have emerged for which there is evidence of an increase in transmissibility, more severe disease, and/or reduced vaccine effectiveness. Effective COVI
Externí odkaz:
https://doaj.org/article/7ddec5d298994b9fb951ab9ada5f2108
Autor:
Vincent Pavot, Catherine Berry, Michael Kishko, Natalie G. Anosova, Lu Li, Tim Tibbitts, Dean Huang, Alice Raillard, Sylviane Gautheron, Cindy Gutzeit, Marguerite Koutsoukos, Roman M. Chicz, Valerie Lecouturier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Waning protective efficacy of mRNA-based booster vaccinations has been observed against newly emerging SARS-CoV-2 variants of concern. In this work, Pavot et al. formulate a monovalent Beta vaccine and demonstrate durable cross-neutralising antibody
Externí odkaz:
https://doaj.org/article/82bb567df3234c4eb6b85d8731df0e1a
Autor:
Vincent Pavot, Catherine Berry, Michael Kishko, Natalie G. Anosova, Dean Huang, Tim Tibbitts, Alice Raillard, Sylviane Gautheron, Cindy Gutzeit, Marguerite Koutsoukos, Roman M. Chicz, Valerie Lecouturier
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Emerging SARS-CoV-2 variants of concern (VOCs) raise questions on vaccine effectiveness. Here, the authors show that an adjuvanted protein-based SARS-CoV-2 spike vaccine booster increases cross-neutralization of VOC, including omicron, in non-human p
Externí odkaz:
https://doaj.org/article/c8ccb39de4d2489d998cfdfb67a40d60
Autor:
Jinyu Liu, Michael Kothe, Jianxin Zhang, Eliud Oloo, Svetlana Stegalkina, Sophia T. Mundle, Lu Li, Jinrong Zhang, Leah E. Cole, Lucianna Barone, Hans-Peter Biemann, Harry Kleanthous, Natalie G. Anosova, Stephen F. Anderson
Publikováno v:
Current Research in Structural Biology, Vol 4, Iss , Pp 96-105 (2022)
Clostridium difficile toxins are the primary causative agents for hospital-acquired diarrhea and pseudomembranous colitis. Numerous monoclonal antibodies (mAbs) targeting different domains of Clostridium difficile toxin have been reported. Here we re
Externí odkaz:
https://doaj.org/article/376b5155381642f9bbe8724343d7e516
Autor:
Sudha Chivukula, Timothy Plitnik, Timothy Tibbitts, Shrirang Karve, Anusha Dias, Donghui Zhang, Rebecca Goldman, Hardip Gopani, Asad Khanmohammed, Ashish Sarode, Dustin Cooper, Heesik Yoon, Younghoon Kim, Yanhua Yan, Sophia T. Mundle, Rachel Groppo, Adrien Beauvais, Jinrong Zhang, Natalie G. Anosova, Charles Lai, Lu Li, Gregory Ulinski, Peter Piepenhagen, Joshua DiNapoli, Kirill V. Kalnin, Victoria Landolfi, Ron Swearingen, Tong-Ming Fu, Frank DeRosa, Danilo Casimiro
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract Recent approval of mRNA vaccines for emergency use against COVID-19 is likely to promote rapid development of mRNA-based vaccines targeting a wide range of infectious diseases. Compared to conventional approaches, this vaccine modality promi
Externí odkaz:
https://doaj.org/article/a7de43f864854e63ba72ae5665205ec9
Autor:
Kirill V. Kalnin, Timothy Plitnik, Michael Kishko, Jinrong Zhang, Donghui Zhang, Adrien Beauvais, Natalie G. Anosova, Tim Tibbitts, Josh DiNapoli, Gregory Ulinski, Peter Piepenhagen, Sheila M. Cummings, Dinesh S. Bangari, Susan Ryan, Po-Wei D. Huang, James Huleatt, Deanne Vincent, Katherine Fries, Shrirang Karve, Rebecca Goldman, Hardip Gopani, Anusha Dias, Khang Tran, Minnie Zacharia, Xiaobo Gu, Lianne Boeglin, Jonathan Abysalh, Jorel Vargas, Angela Beaulieu, Monic Shah, Travis Jeannotte, Kimberly Gillis, Sudha Chivukula, Ron Swearingen, Victoria Landolfi, Tong-Ming Fu, Frank DeRosa, Danilo Casimiro
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Emergency use authorization of COVID vaccines has brought hope to mitigate pandemic of coronavirus disease 2019 (COVID-19). However, there remains a need for additional effective vaccines to meet the global demand and address the potential n
Externí odkaz:
https://doaj.org/article/9fae835e0be047258ae7c50814033e8c
Autor:
Leah E. Cole, Jinrong Zhang, Kristl M. Pacheco, Philippe Lhéritier, Natalie G. Anosova, Julie Piolat, Lingyi Zheng, Nathalie Reveneau
Publikováno v:
Vaccines, Vol 8, Iss 4, p 729 (2020)
While both whole-cell (wP) and acellular pertussis (aP) vaccines have been highly effective at reducing the global pertussis disease burden, there are concerns that compared to wP vaccination, the immune responses to aP vaccination may wane more rapi
Externí odkaz:
https://doaj.org/article/da75338024f846578dc27c478d9c4252
Autor:
David L. Gordon, Harry Kleanthous, Penelope J. Adamson, Natalie G. Anosova, Tom P. Gordon, Alex D. Colella, Tim Chataway, Jing J. Wang
Publikováno v:
Vaccine. 38:2077-2087
Clostridioides difficile infection is the leading cause of nosocomial diarrhoea globally. Immune responses to toxins produced by C. difficile are important in disease progression and outcome. Here, we analysed the anti-toxin A and anti-toxin B serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2314e2ea07f289bd0dd24ca71b071b41
https://doi.org/10.1016/j.vaccine.2019.10.096
https://doi.org/10.1016/j.vaccine.2019.10.096
Autor:
Tim Tibbitts, Cindy Gutzeit, Natalie G. Anosova, Vincent Pavot, Sylviane Gautheron, Valerie Lecouturier, Roman Chicz, Catherine C. Berry, Dean Huang, Michael G. Kishko, Alice Raillard, Marguerite Koutsoukos
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that partly evade neutralizing antibodies has raised concerns of reduced vaccine effectiveness and increased infection. We previously demonstrated in preclinical m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849f0ef5d859aae7a1975cabfda8d15a
https://doi.org/10.21203/rs.3.rs-871537/v1
https://doi.org/10.21203/rs.3.rs-871537/v1
Autor:
Lucianna Barone, Kristl M Pacheco, Lu Li, Fuqin Ma, Christopher Rogers, Utsav Jetley, Yanhua Yan, Nicola Beltraminelli, Laurence Quemeneur, Leah E. Cole, Jinrong Zhang, Harry Kleanthous, Natalie G. Anosova, Stephen Anderson, Sophia Mundle, Jianxin Zhang
Publikováno v:
Vaccine. 37:3892-3901
Clostridium difficile infection (CDI) is the principal cause of nosocomial diarrhea and pseudomembranous colitis associated with antibiotic therapy. The pathological effects of CDI are primarily attributed to toxins A (TcdA) and B (TcdB). Adequate to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992883bcc614bec8ec9d5fb502976504
https://doi.org/10.1016/j.vaccine.2019.05.040
https://doi.org/10.1016/j.vaccine.2019.05.040