Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Natalie Fursov"'
EGF Potentiation of VEGF Production Is Cell Density Dependent in H292 EGFR Wild Type NSCLC Cell Line
Autor:
Daniel J. Ranayhossaini, Jin Lu, John Mabus, Alexis Gervais, Russell B. Lingham, Natalie Fursov
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 17686-17704 (2014)
Non-small cell lung cancer (NSCLC) affects millions of patients each year worldwide. Existing therapies include epidermal growth factor receptor (EGFR) inhibition using small molecules or antibodies with good efficacy. Unfortunately, intrinsic and ac
Externí odkaz:
https://doaj.org/article/866572fa9fc9426eb63aee3a0c3135fe
Autor:
Robert A. Lamb, Yawei Li, Ramachandra Reddy, Brian Jones, Eilyn R. Lacy, Angela Filer, Jin Lu, Catherine Healy, Changbao Liu, Karen E. Duffy, Ted Petley, Sheng-Jiun Wu, Natalie Fursov
Publikováno v:
Molecular immunology. 75
The cell-surface receptor ST2L triggers cytokine release by immune cells upon exposure to its ligand IL-33. To study the effect of ST2L-dependent signaling in different cell types, we generated antagonist antibodies that bind different receptor domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee1f6831b509492255249ceba4d8773
https://pubmed.ncbi.nlm.nih.gov/27294560
https://pubmed.ncbi.nlm.nih.gov/27294560
Autor:
Anuk Das, Natalie Fursov, Geoffrey L. Chupp, Hemanth Ramaprakash, Cory M. Hogaboam, Ugur B. Ismailoglu, Karen E. Duffy, Ana Paula Moreira, Ana Lucia Coelho, Takehiko Shibata, Rachel M. Bredernitz
Publikováno v:
The American Journal of Pathology. 179:104-115
IL-33 and its soluble receptor and cell-associated receptor (ST2L) are all increased in clinical and experimental asthma. The present study addressed the hypothesis that ST2L impairs the therapeutic effects of CpG in a fungal model of asthma. C57BL/6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fc9d8c61250ad789fc136fca28b2dd
https://doi.org/10.1016/j.ajpath.2011.03.032
https://doi.org/10.1016/j.ajpath.2011.03.032
Autor:
Jill Giles-Komar, Erin Johnston, Natalie Fursov, Michael A. Rycyzyn, Haiyan Jiang, Gordon Powers, Karen E. Duffy, Jamie Fisher, Theodore Petley, Adam Cotty
Publikováno v:
Hybridoma. 30:153-162
ST2L is a transmembrane receptor that belongs to the IL-1 receptor family. The receptor is expressed on various cell types including Th2 cells, mast cells, basophils, growth-activated fibroblasts, and vascular endothelial cells. ST2L activation by it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584cc867a0af6035d68b074740c82abf
https://doi.org/10.1089/hyb.2010.0100
https://doi.org/10.1089/hyb.2010.0100
Publikováno v:
Assay and drug development technologies. 9(4)
Interleukin-6 (IL-6) family of cytokines are multifunctional proteins that play an important role in host defenses, acute phase reactions, immune responses, hematopoiesis, and tumorigenesis. The cytokines are produced by various lymphoid and nonlymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13ff17ff28d773f31008038646af1ad
https://pubmed.ncbi.nlm.nih.gov/21294636
https://pubmed.ncbi.nlm.nih.gov/21294636
Autor:
Zhong Zhong, Patrick Maunder, Mei Cong, Natalie Fursov, Jeffrey R. Haskins, Chandrasekaran Vasudevan, Mark Federici, Thomas Livelli
Publikováno v:
Assay and drug development technologies. 3(5)
As cell-based assays are used more commonly in robotic high-throughput compound screening, cells themselves have become critical reagents. Thus, it has become essential to produce cell reagents with high consistency and quality. We experimented with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078e9eb4fa9849599e7601c4726bf564
https://pubmed.ncbi.nlm.nih.gov/16305308
https://pubmed.ncbi.nlm.nih.gov/16305308
Autor:
Peter Haytko, Mei Cong, Thomas Livelli, Zhong Zhong, Mark Federici, Roland Tacke, Natalie Fursov, Michael Platchek
Publikováno v:
Assay and drug development technologies. 3(1)
In this article we describe the use of division-arrested cells for cell-based assays designed for high-throughput screening. Cells are the most critical and variable reagent for cell-based high-throughput screening. The robustness of robotic screenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24786fb2d833330c7e6aca75d8e7b6d3
https://pubmed.ncbi.nlm.nih.gov/15798391
https://pubmed.ncbi.nlm.nih.gov/15798391
Autor:
Natalie Fursov, Neil Cooch, Dean P. Edwards, Leonard P. Freedman, James G. Greger, Sean McLarney, Boris J. Cheskis
Publikováno v:
Molecular and Cellular Biology. 30:1568-1568
Estrogen actions are mediated by a complex interface of direct control of gene expression (the so-called "genomic action") and by regulation of cell signaling/phosphorylation cascades, referred to as the "nongenomic," or extranuclear, action. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c563a7467e9214da76d947a1d2662e
https://doi.org/10.1128/mcb.00090-10
https://doi.org/10.1128/mcb.00090-10
Autor:
Chandrasekaran Vasudevan, Natalie Fursov, Patrick Maunder, Mei Cong, Mark Federici, Jeffrey R. Haskins, Thomas Livelli, Zhong Zhong
Publikováno v:
Assay & Drug Development Technologies; Oct2005, Vol. 3 Issue 5, p515-523, 9p
Autor:
Natalie Fursov, Mei Cong, Mark Federici, Michael Platchek, Peter Haytko, Roland Tacke, Thomas Livelli, Zhong Zhong
Publikováno v:
Assay & Drug Development Technologies; Feb2005, Vol. 3 Issue 1, p7-15, 9p