Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Natalie Dowell-Mesfin"'
Autor:
Matthew R. Hynd, Karen L. Smith, William Shain, Natalie Dowell-Mesfin, Hong Wu, Bruce J. Herron, Sung June Kim
Publikováno v:
Journal of Neuroscience Methods. 203:398-406
Neural prosthetic devices are showing increasing clinical use for the treatment of a variety of neurological disorders. However the functions on these devices are often limited due to an inability to effectively and chronically interface with neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cadffccde2691b011b264fd273aa4654
https://doi.org/10.1016/j.jneumeth.2011.09.023
https://doi.org/10.1016/j.jneumeth.2011.09.023
Autor:
Natalie Dowell-Mesfin, William Shain, Matthew R. Hynd, James N. Turner, Shalin J. Jhaveri, Christopher K. Ober
Publikováno v:
Biomacromolecules. 10:174-183
Local pharmacological intervention may be needed to ensure the long-term performance of neural prosthetic devices because of insertion-related neuron loss and reactive cell responses that form compact sheaths, leading to decreased device performance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e83ae1d809c2239981f83fe6137309
https://doi.org/10.1021/bm801101e
https://doi.org/10.1021/bm801101e
Autor:
William Shain, Matthew R. Hynd, Sang Beom Jun, Badrinath Roysam, Sung June Kim, Yousef Al-Kofahi, Natalie Dowell-Mesfin
Publikováno v:
Journal of Neural Engineering. 5:203-213
Polyacrylamide and poly(ethylene glycol) diacrylate hydrogels were synthesized and characterized for use as drug release and substrates for neuron cell culture. Protein release kinetics was determined by incorporating bovine serum albumin (BSA) into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4b61d1917d3d4647866fb8ccdf2f2e
https://doi.org/10.1088/1741-2560/5/2/011
https://doi.org/10.1088/1741-2560/5/2/011
Autor:
David L. Martin, William Shain, Matthew R. Hynd, John P. Frampton, Natalie Dowell-Mesfin, Mary-Rose Burnham, James N. Turner
Publikováno v:
Journal of Biomedical Materials Research Part A. :347-354
Patterning of multiple proteins and enzymes onto biocompatible surfaces can provide multiple signals to control cell attachment and growth. Acrylamide-based hydrogels were photo-polymerized in the presence of streptavidin-acrylamide, resulting in pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c22942928517abe70c5dec03386c137
https://doi.org/10.1002/jbm.a.31002
https://doi.org/10.1002/jbm.a.31002
Autor:
Badrinath Roysam, M. A. Abdul-Karim, Murat Yuksel, S. Kalyanaraman, Natalie Dowell-Mesfin, A. Jeromin
Publikováno v:
IEEE Transactions on Image Processing. 14:1338-1350
An automated method is presented for selecting optimal parameter settings for vessel/neurite segmentation algorithms using the minimum description length principle and a recursive random search algorithm. It trades off a probabilistic measure of imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c9f7431b024d377654428d22bb7d2c
https://doi.org/10.1109/tip.2005.852462
https://doi.org/10.1109/tip.2005.852462
Autor:
Andrew J. Spence, K.L. Smith, Conrad D. James, Harold G. Craighead, William Shain, Rifat J. Hussain, Michael Isaacson, Natalie Dowell-Mesfin, James N. Turner
Publikováno v:
IEEE Transactions on Biomedical Engineering. 51:1640-1648
Neuronal cell networks have been reconstructed on planar microelectrode arrays (MEAs) from dissociated hippocampal pyramidal neurons. Microcontact printing (microCP) and a photoresist-liftoff method were used to selectively localize poly-L-lysine (PL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1155b478934f1a1a9537dd168fe55d
https://doi.org/10.1109/tbme.2004.827252
https://doi.org/10.1109/tbme.2004.827252
Autor:
James N. Turner, William Shain, S. Lasek, Khalid Al-Kofahi, Badrinath Roysam, Donald H. Szarowski, Ali Can, Natalie Dowell-Mesfin
Publikováno v:
IEEE Transactions on Information Technology in Biomedicine. 7:302-317
This paper presents a method to exploit rank statistics to improve fully automatic tracing of neurons from noisy digital confocal microscope images. Previously proposed exploratory tracing (vectorization) algorithms work by recursively following the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fdb36ad0e1b573a1c5e895e240f925
https://doi.org/10.1109/titb.2003.816564
https://doi.org/10.1109/titb.2003.816564
Autor:
Sang Beom Jun, William Shain, Sung June Kim, Natalie Dowell-Mesfin, Matthew R. Hynd, Karen L. Smith
Publikováno v:
Medicalbiological engineeringcomputing. 48(9)
Patch-clamping or microelectrode arrays (MEA) are conventional methods to monitor the electrical activity in biological neural networks in vitro. Despite the effectiveness of these techniques, there are disadvantages including the limited number of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4174b124f5430e36f737df596190028b
https://pubmed.ncbi.nlm.nih.gov/20490941
https://pubmed.ncbi.nlm.nih.gov/20490941
Autor:
K.L. Smith, Sang Beom Jun, William Shain, Sung June Kim, James N. Turner, M. Hynd, Natalie Dowell-Mesfin
Publikováno v:
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2005
Rectangular networks of rat hippocampal neurons have been produced on microelectrode arrays (MEAs). The crossing points of networks were located at the recording electrode sites by aligned microcontact printing (muCP) technique. Polydimethysiloxane (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fd736c56fa3d76bdd6cd9d3c5c6112
https://pubmed.ncbi.nlm.nih.gov/17282041
https://pubmed.ncbi.nlm.nih.gov/17282041
Publikováno v:
Journal of neuroscience methods. 162(1-2)
Biochemical surface modification has been used to direct cell attachment and growth on a biocompatible gel surface. Acrylamide-based hydrogels were photo-polymerized in the presence of an acroyl-streptavidin monomer to create planar, functionalized s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9ee68246060a60fef43d75971d29a9
https://pubmed.ncbi.nlm.nih.gov/17368788
https://pubmed.ncbi.nlm.nih.gov/17368788