Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Natalie Donin"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The complement system participates in the pathogenesis of many diseases. Complement activation produces several active protein complexes and peptides, including the terminal C5b-9 complexes. It was reported that C5b-9 complexes insert into the plasma
Externí odkaz:
https://doaj.org/article/3c4313197ff34f9bb281b940a942d8ad
Autor:
Zvi Fishelson, Osnat Bairey, Ritta Jubran, Natalie Donin, Moran Saar-Ray, Anna Wawruszak, Lea Ziporen
Publikováno v:
International Journal of Oncology.
Cancer cells have developed numerous strategies to maintain their proliferative capacity and to withstand different kinds of stress. The mitochondrial stress‑70 protein named glucose regulated protein 75 (GRP75), also known as mortalin, is an intri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de83b71c5cf3450209bd22982750a018
https://doi.org/10.3892/ijo.2020.5101
https://doi.org/10.3892/ijo.2020.5101
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
The complement system participates in the pathogenesis of many diseases. Complement activation produces several active protein complexes and peptides, including the terminal C5b-9 complexes. It was reported that C5b-9 complexes insert into the plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45d49055d0f312cb346c2b3a4c0f031
https://pubmed.ncbi.nlm.nih.gov/29527209
https://pubmed.ncbi.nlm.nih.gov/29527209
Publikováno v:
Molecular Immunology. 47:310-317
Cell death and survival signals activated by the complement membrane attack complex C5b-9 play important roles in complement-associated diseases and in antibody-based cancer therapy. Here, we investigated the involvement of the JNK mitogen-activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ea3c1d0e1fd576ac70814518f46dfa
https://doi.org/10.1016/j.molimm.2009.09.016
https://doi.org/10.1016/j.molimm.2009.09.016
Publikováno v:
The Journal of Immunology. 182:515-521
The membrane attack complex (MAC) of the complement system induces a necrotic-type cell death. Earlier findings suggested that Bcl-2 protects cells from MAC-induced necrosis. Here we examined the involvement of Bid, a proapoptotic protein, in MAC-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0103e9009cde3f78a50951a8187050e
https://doi.org/10.4049/jimmunol.182.1.515
https://doi.org/10.4049/jimmunol.182.1.515
Publikováno v:
Molecular Immunology. 40:109-123
Monoclonal antibodies (mAbs) are being increasingly used in cancer therapy owing to their ability to recognize specifically cancer cells and to activate complement- and cell-mediated cytotoxicity and/or to induce growth arrest or apoptosis. The thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e597a54b8eb0923eab2a9315991d06eb
https://doi.org/10.1016/s0161-5890(03)00112-3
https://doi.org/10.1016/s0161-5890(03)00112-3
Autor:
Katrin Jurianz, Michael Kirschfink, Natalie Donin, Lea Ziporen, Zvi Fishelson, Stefan Schultz
Publikováno v:
Clinical and Experimental Immunology. 131:254-263
SUMMARY Nucleated cells employ several strategies to evade killing by homologous complement. We studied complement resistance in the human carcinoma cell lines (CA) T47D (mammary), SKOV3 (ovarian), and PC-3 (prostate) with emphasis on the following m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0527e6412aa79ac2b90f7e6a11bd7fcd
https://doi.org/10.1046/j.1365-2249.2003.02066.x
https://doi.org/10.1046/j.1365-2249.2003.02066.x
Autor:
Dina Katzenelson, Asher Pinchassov, M. Michowitz, Jehuda Hiss, S Kay, Ginnette Schibi, Natalie Donin, Judith Leibovici
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1497:37-50
Disturbance of apoptosis is an established factor in tumorigenesis. The role of apoptosis in tumor progression is not yet clear. In the present study we compared the tendency to spontaneous apoptosis (and the proliferative capacity) of tumor cells de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75cbfaa9cba6329436c6b3049e42f6f9
https://doi.org/10.1016/s0167-4889(00)00037-9
https://doi.org/10.1016/s0167-4889(00)00037-9
Autor:
Natalie Donin, S Kay, M. Michowitz, Judith Sinai, Judith Leibovici, Ginnette Schibi, Annette Siegal, Dina Katzenelson
Publikováno v:
Cancer Investigation. 18:702-714
Dysregulation in apoptotic cell death has recently emerged as a factor in tumorigenesis, but its effect in tumor progression is not yet established. In the present study we evaluated the levels of proliferative and apoptotic cell fractions in a T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21ce20ea3b928c31b405c71662d8f30
https://doi.org/10.3109/07357900009012202
https://doi.org/10.3109/07357900009012202
Autor:
J Ravia, Asher Pinchassov, M. Michowitz, Dina Katzenelson, Judith Leibovici, Natalie Donin, Judith Sinai, Annette Siegal, S Kay
Publikováno v:
APOPTOSIS. 4:429-440
Resistance to apoptosis may be related to tumor progression, due to the implications it might have on both tumor mass and genetic instability. We compared the tendency to spontaneous apoptosis and the proliferative capacity of metastatic growths of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9828ee096590f16c05a4f01f18b261a9
https://doi.org/10.1023/a:1009648325350
https://doi.org/10.1023/a:1009648325350