Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Natalie C Knox"'
Autor:
Shelley W Peterson, Natalie C Knox, George R Golding, Shaun D Tyler, Andrea D Tyler, Philip Mabon, Joanne E Embree, Fiona Fleming, Sergio Fanella, Gary Van Domselaar, Michael R Mulvey, Morag R Graham
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152493 (2016)
Whereas the infant gut microbiome is the subject of intense study, relatively little is known regarding the nares microbiome in newborns and during early life. This study aimed to survey the typical composition and diversity of human anterior nare mi
Externí odkaz:
https://doaj.org/article/748a0a136fd04403bea4ba0bf911e004
Autor:
Andrea D Tyler, Sara Christianson, Natalie C Knox, Philip Mabon, Joyce Wolfe, Gary Van Domselaar, Morag R Graham, Meenu K Sharma
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148676 (2016)
The advent and widespread application of next-generation sequencing (NGS) technologies to the study of microbial genomes has led to a substantial increase in the number of studies in which whole genome sequencing (WGS) is applied to the analysis of m
Externí odkaz:
https://doaj.org/article/6c8c0ae7433f4d2cbf594a9ef490358a
Autor:
Jake C. Szamosi, Jessica D. Forbes, Julia K. Copeland, Natalie C. Knox, Shahrokh Shekarriz, Laura Rossi, Morag Graham, Christine Bonner, David S. Guttman, Gary Van Domselaar, Michael G. Surette, Charles N. Bernstein
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
BackgroundIn studies evaluating the microbiome, numerous factors can contribute to technical variability. These factors include DNA extraction methodology, sequencing protocols, and data analysis strategies. We sought to evaluate the impact these fac
Externí odkaz:
https://doaj.org/article/7b50db6529844fc89e269b43d733d669
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 16, Iss , Pp 108-120 (2018)
Clinical metagenomics (CMg) is the discipline that refers to the sequencing of all nucleic acid material present within a clinical specimen with the intent to recover clinically relevant microbial information. From a diagnostic perspective, next-gene
Externí odkaz:
https://doaj.org/article/e7636ce965ee47499a7f2e9bcb308e33
Autor:
Geoffrey, Liang, Feng, Zhu, Ali I, Mirza, Amit, Bar-Or, Charles N, Bernstein, Christine, Bonner, Jessica D, Forbes, Morag, Graham, Janace, Hart, Natalie C, Knox, Ruth Ann, Marrie, Julia, O'Mahony, Gary, Van Domselaar, E Ann, Yeh, Yinshan, Zhao, Brenda, Banwell, Emmanuelle, Waubant, Helen, Tremlett
Publikováno v:
Multiple Sclerosis Journal. 28:1819-1824
Objective: Examine if the gut microbiota composition changes across repeated samples in paediatric-onset multiple sclerosis (MS) or monophasic-acquired demyelinating syndromes (monoADS). Methods: A total of 36 individuals (18 MS/18 monoADS) with ⩾2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd46d94353907fa85f7f44a9198a6ebc
https://doi.org/10.1177/13524585221079533
https://doi.org/10.1177/13524585221079533
Autor:
Helen Tremlett, Feng Zhu, Douglas Arnold, Amit Bar‐Or, Charles N. Bernstein, Christine Bonner, Jessica D. Forbes, Morag Graham, Janace Hart, Natalie C. Knox, Ruth Ann Marrie, Ali I. Mirza, Julia O’Mahony, Gary Van Domselaar, E. Ann Yeh, Yinshan Zhao, Brenda Banwell, Emmanuelle Waubant, the US Network of Pediatric MS Centers, the Canadian Pediatric Demyelinating Disease Network
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Vol 8, Iss 12, Pp 2252-2269 (2021)
Annals of Clinical and Translational Neurology, Vol 8, Iss 12, Pp 2252-2269 (2021)
Objective To examine the gut microbiota in individuals with and without pediatric‐onset multiple sclerosis (MS). Methods We compared stool‐derived microbiota of Canadian Pediatric Demyelinating Disease Network study participants ≤21 years old,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ed95ef510c7295e2c5a95b3c6d9a43
https://doi.org/10.1002/acn3.51476
https://doi.org/10.1002/acn3.51476
Autor:
Raymond S. W. Tsang, Gary Van Domselaar, Julianne V. Kus, Kristy Hayden, Tauqeer Ahmad, George Zahariadis, Marina Ulanova, Paul Van Caeseele, Kami Kandola, Michelle Shuel, Michael Patterson, Brendan Hanley, Gregory J. Tyrrell, Richard Garceau, Greg J. German, Linda Hoang, Natalie C. Knox, David Haldane, Brigitte Lefebvre, Jessica Minion
Publikováno v:
Canadian Journal of Microbiology. 66:99-110
This study examined the phylogenetic structure of serotype a Haemophilus influenzae (Hia) isolates recovered from patients in Canada. Hia isolates from 490 separate patients and an American Type Culture Collection (ATCC) strain were analyzed by multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d552812dc76b45131741e54456381412
https://doi.org/10.1139/cjm-2019-0406
https://doi.org/10.1139/cjm-2019-0406
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Chronic intestinal inflammation and microbial dysbiosis are hallmarks of colorectal cancer (CRC) and inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis. However, the mechanistic relationship between gut dysbiosis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fa145b0bc9fcccd39af9d47dd4bf90
Autor:
Natalie C. Knox, Charles N. Bernstein, Jessica D. Forbes, Gary Van Domselaar, Christy-Lynn Peterson
Publikováno v:
American Journal of Gastroenterology. 114:1051-1070
There is a growing appreciation for the role of the gut microbiome in human health and disease. Aided by advances in sequencing technologies and analytical methods, recent research has shown the healthy gut microbiome to possess considerable diversit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806ab34a4248907c318b622d84387f6b
https://doi.org/10.14309/ajg.0000000000000305
https://doi.org/10.14309/ajg.0000000000000305
Publikováno v:
Current Treatment Options in Gastroenterology. 17:115-126
This review aims to highlight recent research on the gut microbiome in IBD and the application of microbiome-modulating therapies for the treatment of IBD including the use of the microbiome as an indicator for disease severity and treatment response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdc57e0d5fc4716a0b32e52fa9dee28
https://doi.org/10.1007/s11938-019-00221-w
https://doi.org/10.1007/s11938-019-00221-w