Výsledky vyhledávání - "Natalie Böhm"

Akademický článek

Characterising meaningful patient and public involvement in the pharmaceutical industry research setting: a retrospective quality assessment

Autor: Jennifer Preston, Natalie Bohm, Adit Bassi, Angela Davies, Kamil Sterniczuk, Berkeley Phillips, Sally-Anne Dews, Sean Buckland, Lucy Clements, Rachel Daley, Sophie Evett, Samantha Howland, Emma Kinloch, Gareth Powell

Publikováno v: BMJ Open, Vol 13, Iss 8 (2023)

Objectives Patient and public involvement (PPI) in clinical research has a well-established infrastructure in the UK, and while there has been good progress within pharmaceutical-industry-sponsored research, further improvements are still needed. Thi

Externí odkaz: https://doaj.org/article/52fba11a97d74cb9ad889632a1e7f0e7

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FK506-binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells

Autor: Klaus Aktories, Katharina Ernst, Natalie Böhm, Michel R. Popoff, Simon Langer, Holger Barth, Carsten Schwan, Gunter Fischer, Eva Kaiser

Publikováno v: Cellular Microbiology
Cellular Microbiology, Wiley, 2012, 14 (8), pp.1193-1205. ⟨10.1111/j.1462-5822.2012.01788.x⟩
Cellular Microbiology, Wiley, 2012, 14 (8), pp.1193-1205. 〈10.1111/j.1462-5822.2012.01788.x〉
Cellular Microbiology, 2012, 14 (8), pp.1193-1205. ⟨10.1111/j.1462-5822.2012.01788.x⟩

International audience; The binary Clostridium botulinum C2 toxin consists of the binding/translocation component C2IIa and the separate enzyme component C2I. C2IIa delivers C2I into the cytosol of eukaryotic target cells where C2I ADP-ribosylates ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232049c54ee0d27ab7a0671407f6cdf8
https://hal-pasteur.archives-ouvertes.fr/pasteur-01762818

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Akademický článek

Living with Ulcerative Colitis Study (LUCY) in England: a retrospective study evaluating healthcare resource utilisation and direct healthcare costs of postoperative care in ulcerative colitis

Autor: Joseph C Cappelleri, Matthew J Brookes, Natalie Bohm, John Waller, Irene Modesto, Marco D DiBonaventura, Ruth Mokgokong, Danielle Bargo

Publikováno v: BMJ Open Gastroenterology, Vol 7, Iss 1 (2020)

Objective Ulcerative colitis (UC) is a lifelong, relapsing-remitting disease. Patients non-responsive to pharmacological treatment may require a colectomy. We estimated pre-colectomy and post-colectomy healthcare resource utilisation (HCRU) and costs

Externí odkaz: https://doaj.org/article/c5d9c17e64254fdcb9025b0823da3aa2

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Akademický článek

Sarcopenic Obesity in Heart Failure With Preserved Ejection Fraction

Autor: Danielle L. Kirkman, Natalie Bohmke, Hayley E. Billingsley, Salvatore Carbone

Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)

Heart failure with preserved ejection fraction (HFpEF) is a public health epidemic that is projected to double over the next two decades. Despite the high prevalence of HFpEF, there are currently no FDA approved therapies for health-related outcomes

Externí odkaz: https://doaj.org/article/f804a0ec57484b919ab0accec2296537

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Akademický článek

Impact of physical activity on monocyte subset CCR2 expression and macrophage polarization following moderate intensity exercise

Autor: Anson M. Blanks, Thomas T. Wagamon, Lindsay Lafratta, Mabel G. Sisk, Morgan B. Senter, Lauren N. Pedersen, Natalie Bohmke, Attiya Shah, Virginia L. Mihalick, R. Lee Franco

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 2, Iss , Pp 100033- (2020)

Coronary artery disease (CAD) is an immune-mediated disease in which CCR2 attracts classical, intermediate, and non-classical monocytes to the arterial intima where they differentiate to macrophages. Balance between pro-inflammatory M1 and anti-infla

Externí odkaz: https://doaj.org/article/1eb46f0b8e9e4ccd854fd3eb19772333

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Akademický článek

Tofacitinib for the treatment of moderately to severely active ulcerative colitis: a systematic review, network meta-analysis and economic evaluation

Autor: Emily Wright, Christoph Lohan, Alex Diamantopoulos, Corinne LeReun, Natalie Bohm, Laura Marie Sawyer

Publikováno v: BMJ Open Gastroenterology, Vol 6, Iss 1 (2019)

Background and aims In the UK, treatments for patients with moderately to severely active ulcerative colitis who have an inadequate response to conventional therapies comprise four biological therapies—the tumour necrosis factor inhibitor (TNFi) ag

Externí odkaz: https://doaj.org/article/1f1ecced7b13469b8d58ece1b71d353f

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