Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial

Autor: Bijoy K Menon, Brian H Buck, Nishita Singh, Yan Deschaintre, Mohammed A Almekhlafi, Shelagh B Coutts, Sibi Thirunavukkarasu, Houman Khosravani, Ramana Appireddy, Francois Moreau, Gord Gubitz, Aleksander Tkach, Luciana Catanese, Dar Dowlatshahi, George Medvedev, Jennifer Mandzia, Aleksandra Pikula, Jai Shankar, Heather Williams, Thalia S Field, Alejandro Manosalva, Muzaffar Siddiqui, Atif Zafar, Oje Imoukhuede, Gary Hunter, Andrew M Demchuk, Sachin Mishra, Laura C Gioia, Shirin Jalini, Caroline Cayer, Stephen Phillips, Elsadig Elamin, Ashkan Shoamanesh, Suresh Subramaniam, Mahesh Kate, Gregory Jacquin, Marie-Christine Camden, Faysal Benali, Ibrahim Alhabli, Fouzi Bala, MacKenzie Horn, Grant Stotts, Michael D Hill, David J Gladstone, Alexandre Poppe, Arshia Sehgal, Qiao Zhang, Brendan Cord Lethebe, Craig Doram, Ayoola Ademola, Michel Shamy, Carol Kenney, Tolulope T Sajobi, Richard H Swartz, Abhilekh Srivastava, Ahmed M Aljammaz, Akintomide Femi Akindotun, Albert Y Jin, Alexander Fraser, Alexander V Khaw, Alexandru Lemnaru, Alisia Southwell, Alnar Ramji, Alonso Alvarado-Bolaños, Amr Mouminah, Amro B Lahlouh, Amy Y Yu, Anas Alrohimi, Andre Lavoie, Andrea Rogge, Andrew Micieli, Andrew Linh Nguyen, Angelique Callaghan-Brown, Anita Florendo-Cumbermack, Ankur Wadhwa, Ann-Marie Beaudoin, Anne Cayley, Anne Marie Liddy, Anurag Trivedi, Aristeidis H Katsanos, Ashfaq Shuaib, Asif Javed Butt, Olena Bereznyakova, Beth Beauchamp, Breane Mahlitz, Brett R Graham, Brian Dewar, Bryce A Durafourt, Caitlin Holtby, Caitlin S Jackson-Tarlton, Caitlyn Bockus, Caroline Stephenson, Camille Galloway, Céline Odier, Charles Deacon, Charlotte Zerna, Chetan C Vekhande, Christian Bocti, Christian Stapf, Christine Hawkes, Christine Anne Stables, Chrysi Bogiatzi, Claudia Rodriguez, Claudia Candale-Radu, Colleen Murphy, Courtney Sarah Casserly, Daniel Fok, Danielle de Sa Boasquevisque, Daryl Wile, David Volders, Demetrios J Sahlas, Elaine Shand, Elena Adela Cora, Eliane Di Battista, Eileen Stewart, Emily Junk, Emma L Harrison, Eric Frenette, Ericka Teleg, Eslam Abdellah, Esseddeeg Ghrooda, Farhana Akthar, François Evoy, Gary M Klein, Genoveva Maclean, Glen C Jickling, Glenda Hawthorne, Gordon Boyd, Gregory Walker, Gustavo Saposnik, H Lee Lau, Hanan E Badr, Hassanain Toma, Hayrapet Kalashyan, Hugo Marion-Moffet, Ian Grant, Idris Fatakdawala, Isabelle Beaulieu-Boire, Janice Williams, Jaskiran Brar, Jean Rivest, Jeffrey Z Wang, Jessica Dawe, Jillian Stang, Joanne Day, Jodi Miller, Johnathon Gorman, Julia Jasmine Hopyan, Julian Lee, Julie Kromm, Kaitlyn Foster, Kanchana Ratnayake, Kanjana S Perera, Karina Villaluna Murray, Karla Ryckborst, Katie Lin, Kayla Sage, Keithan Sivakuma, Kelly A MacDonald, Kelvin Kuan Ng, Ketki Merchant, Khurshid Khan, Kimia Ghavami, Kyra Johnston, Lauren M Mai, Leah White, Lee Barratt, Linda Longpre, Lisa Crellin, Lissa Peeling, Lori Piquette, Lysa Boissé Lomax, Mahsa Sadeghi, Maneesha Kamra, Manuel Lavoie-April, Margaret Moores, Maria Bres Bullrich, Marie McClelland, Marina Salluzzi, Mark Wilcox, Mark I Boulos, Martha Marko, Matthew Boyko, Maude Lantagne-Hurtubise, May Adel AlHamid, Mays Shawawrah, Michael E Kelly, Michael W D Thorne, Miguel Bussiere, Ming Yin Dominc Tse, Mowad Benguzzi, Mukul Sharma, Myles Horton, Nancy Newcommon, Nandy-Shelwine Simon, Natalie E Parks, Nazeem Sultan, Nevena Markovic, Nicole Daneault, Noman Ishaque, Paige Fairall, Pawel B Kostyrko, Peter K Stys, Philip Teal, Philippe Couillard, Princess King-Azote, Quentin Collier, Rachel Epp, Radhika Nair, Raed A Joundi, Rajive Jassal, Raphael Schneider, Reza Hosseini, Rosalie Bouchard, Ruth Whelan, S Regan Cooley, Sajeevan Sujanthan, Salman Mansoor, Samuel Yip, Sanchea Wasyliw, Sean W. Taylor, Sebastian Friedman, Sharan Mann, Sharleen Weese Maley, Sherry Chiasson, Sherry Xueying Hu, Shorog Althubait, Shuhira Himed, Shuo Chen, Simerpreet S Bal, Stacey A Page, Stacey D Beck, Stephanie Woodroffe, Stephanie D Reiter, Stephen van Gaal, Steven Ray Peters, Sultan Darvesh, Supriya Save, Susan Alcock, Susannah Piercey, Suzie Adam, Sylvie Gosselin, Tess Fitzpatrick, Thomas-Louis Perron, Tim Stewart, Timothy J Benstead, Vishaya Naidoo, Wasan Abd Wahab, Wiesław Oczkowski, William Kingston, William Leduc, William T H To, Yeyao Joe Yu, Zhongyu A Liu, Ziad Ezzat Aljundi

Publikováno v: Lancet (London, England). 400(10347)

Intravenous thrombolysis with alteplase bolus followed by infusion is a global standard of care for patients with acute ischaemic stroke. We aimed to determine whether tenecteplase given as a single bolus might increase reperfusion compared with this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc5e53429743ba8fd155e21c582c468
https://pubmed.ncbi.nlm.nih.gov/35779556

Navigating the TOR of Multiple Sclerosis

Autor: Natalie E Parks

Publikováno v: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 47(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8d07dcbbb202654072901c941f14ed
https://pubmed.ncbi.nlm.nih.gov/32326985

Comorbidity and persistence of disease-modifying therapy use in relapsing remitting multiple sclerosis

Autor: Pantelis Andreou, Virender Bhan, Ruth Ann Marrie, John D. Fisk, Natalie E Parks, Susan Kirkland

Publikováno v: Multiple Sclerosis and Related Disorders. 56:103249

Background Comorbidity decreases the likelihood of initiating disease-modifying therapy (DMT) for multiple sclerosis (MS). Our objective was to characterize the relationship between comorbidity and initial DMT persistence along with reasons for DMT d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20700baffbdd17082ba241e4281fa5d7
https://doi.org/10.1016/j.msard.2021.103249

Effects of Magnitude on the Displacement of Leisure Items by Edible Items During Preference Assessments

Autor: Mindy Scheithauer, Christina A. Simmons, Colin S. Muething, Natalie A. Parks, Seth B. Clark, Nathan A. Call

Publikováno v: Behavior modification. 44(5)

Studies on preference assessments have shown that when both edible and leisure items are compared, edible items tend to displace leisure items in preference hierarchies. However, the mechanisms behind this process are currently unclear. One possibili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611068de9874ce1a4c267d2bb5630c12
https://pubmed.ncbi.nlm.nih.gov/30983381

Neuroradiologic manifestations of Erdheim-Chester disease

Autor: Natalie E. Parks, Jay Mandrekar, Ronald S. Go, Gaurav Goyal, W. Oliver Tobin

Publikováno v: Neurology. Clinical practice. 8(1)

BackgroundWe describe the neuroradiologic features of a cohort of patients with Erdheim-Chester disease.MethodsWe assessed patients at Mayo Clinic Rochester between January 1, 1990, and July 31, 2016, with pathologically confirmed Erdheim-Chester dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44da6c0d18e7896a43a4563e6707c689
https://pubmed.ncbi.nlm.nih.gov/29517068