Epigenetic and transcriptome responsiveness to ER modulation by tissue selective estrogen complexes in breast epithelial and breast cancer cells.

Autor: Terri L Messier, Joseph R Boyd, Jonathan A R Gordon, Coralee E Tye, Natalie A Page, Rabail H Toor, Sayyed K Zaidi, Barry S Komm, Seth Frietze, Janet L Stein, Jane B Lian, Gary S Stein

Publikováno v: PLoS ONE, Vol 17, Iss 7, p e0271725 (2022)

Selective estrogen receptor modulators (SERMs), including the SERM/SERD bazedoxifene (BZA), are used to treat postmenopausal osteoporosis and may reduce breast cancer (BCa) risk. One of the most persistent unresolved questions regarding menopausal ho

Externí odkaz: https://doaj.org/article/23747e72e03144299f6791559e911b97

LncMIR181A1HG is a novel chromatin-bound epigenetic suppressor of early stage osteogenic lineage commitment

Autor: Coralee E. Tye, Prachi N. Ghule, Jonathan A. R. Gordon, Fleur S. Kabala, Natalie A. Page, Michelle M. Falcone, Kirsten M. Tracy, Andre J. van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)

Abstract Bone formation requires osteogenic differentiation of multipotent mesenchymal stromal cells (MSCs) and lineage progression of committed osteoblast precursors. Osteogenic phenotype commitment is epigenetically controlled by genomic (chromatin

Externí odkaz: https://doaj.org/article/cb869d076f7b42c0a921afee30acdf08

Regulation of osteogenesis by long noncoding RNAs: An epigenetic mechanism contributing to bone formation

Autor: Michelle M. Falcone, Natalie A. Page, Janet L. Stein, Jane B. Lian, Coralee E. Tye, Gary S. Stein, Joseph R. Boyd

Publikováno v: Connective tissue research. 59(sup1)

Long noncoding RNAs (lncRNAs) have recently emerged as novel regulators of lineage commitment, differentiation, development, viability, and disease progression. Few studies have examined their role in osteogenesis; however, given their critical and w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9458f5e1a62944203678a2da38b00b
https://pubmed.ncbi.nlm.nih.gov/29745821

Selective expression of long non-coding RNAs in a breast cancer cell progression model

Autor: Natalie A. Page, Kirsten Tracy, Gary S. Stein, Andrew J. Fritz, Coralee E. Tye, Jane B. Lian, Janet L. Stein

Publikováno v: Journal of cellular physiology. 233(2)

Long non-coding RNAs (lncRNAs) are acknowledged as regulators of cancer biology and pathology. Our goal was to perform a stringent profiling of breast cancer cell lines that represent disease progression. We used the MCF-10 series, which includes the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f7e4ed9cb212a59576f917568e14ff
https://pubmed.ncbi.nlm.nih.gov/28488769

Contents Vol. 141, 2006

Autor: S. Ma, Kazuo Takahashi, Per Stahl Skov, Masatoshi Nakazawa, Zahra Pourpak, Seiko Shigeta, B. Ho, Mutsuhiko Minami, Josef J.M. van der Steen, Takeshi Kato, Asghar Aghamohammadi, Mehdi Yeganeh, Claude André, Guy Brusselle, Ali Salavati, Thomas Fuchs, Toshio Miyawaki, Tsutomu Hirasawa, Naoya Yoshioka, Maurilia Fiorini, Janne Björkander, Tjeerd Blacquière, Sina Abdollahzade, Tania Maes, Kouichi Mitsuishi, Masatosi Oshita, Ko Okumura, Neil Goodman, Yuko Kikuchi, Guy Joos, Kazuo Nishikawa, Nicole Graf, Katarzyna Wosińska, Graham Jones, Johannes Ring, Mikiko Ota, Francisque Leynadier, Luigi D. Notarangelo, Zenro Ikezawa, Graeme J. Stewart, Gabriela Senti, Paul G.H. Mulder, Ruben Oliver, Hideoki Ogawa, Alessandro Maselli Del Giudice, A. Lee, Gian Luigi Marseglia, Nima Parvaneh, Norihiko Fukuoka, Tsunehiro Aki, T.-N. Tan, H. P. van Bever, Ana I. Tabar, B.W. Lee, Nima Rezaei, Seiji Kawamoto, Francesca Goffi, D.L.M. Goh, Monica Arvidsson, Michiko Aihara, Chiaki Iwamura, Sabina Rak, Floriano Bonifazi, Hans de Groot, Lian Duan, Matteo Gelardi, Setsuko Matsukura, Shigaku Ikeda, Marta Anda, Takaharu Hayashi, Pål Johansen, L.P. Shek, Roy Gerth van Wijk, Chunping Xu, Michaela Allen, Maria Luisa Fiorella, Wei He, Brunello Wüthrich, Nicolette W. de Jong, Halina Plewako, Bettina M. Prinz Vavricka, Hirokazu Kanegane, Giorgio Ciprandi, Kazuhisa Ono, Ali Akbar Amirzargar, Alessandro Plebani, Thomas M. Kündig, Shahram Teimourian, S. Galvain, Natalie S. Page, P. Sangsupawanich, Maria Beatrice Bilò, Romain Pauwels, Ken R. Bracke, Lena Håkansson, Ken Takeda, Karim Vermaelen, Catherine Klersy, Christ C. Smeekens, Toshiro Takai, Ingel K. Demedts, Chi Ma, Nima Pouladi, Mostafa Moin, Teresa Candreva

Publikováno v: International Archives of Allergy and Immunology. 141:419-421

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b86ed665d57b324e22f231a17a44dac
https://doi.org/10.1159/000097037