Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Natalie, Krahmer"'
Autor:
Perla Cota, Özüm Sehnaz Caliskan, Aimée Bastidas-Ponce, Changying Jing, Jessica Jaki, Lama Saber, Oliver Czarnecki, Damla Taskin, Anna Karolina Blöchinger, Thomas Kurth, Michael Sterr, Ingo Burtscher, Natalie Krahmer, Heiko Lickert, Mostafa Bakhti
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101853- (2024)
Objective: The consequences of mutations in genes associated with monogenic forms of diabetes on human pancreas development cannot be studied in a time-resolved fashion in vivo. More specifically, if recessive mutations in the insulin gene influence
Externí odkaz:
https://doaj.org/article/9e1e1763e24b47d79c646e24cd6e365f
Autor:
Konxhe Kulaj, Alexandra Harger, Michaela Bauer, Özüm S. Caliskan, Tilak Kumar Gupta, Dapi Menglin Chiang, Edward Milbank, Josefine Reber, Angelos Karlas, Petra Kotzbeck, David N. Sailer, Francesco Volta, Dominik Lutter, Sneha Prakash, Juliane Merl-Pham, Vasilis Ntziachristos, Hans Hauner, Michael W. Pfaffl, Matthias H. Tschöp, Timo D. Müller, Stefanie M. Hauck, Benjamin D. Engel, Jantje M. Gerdes, Paul T. Pfluger, Natalie Krahmer, Kerstin Stemmer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Extracellular vesicles (EVs) convey inter-organ communication in health and disease. Here, the authors report that adipocyte-derived EVs isolated from insulin-resistant obese but not lean male mice stimulate insulin secretion via the targeted transfe
Externí odkaz:
https://doaj.org/article/7a980c15ae974d7993862a2be969cbb9
Autor:
Francesca Sacco, Giorgia Massacci, Venafra Veronica, Valeria Bica, Sara Latini, Thomas Fischer, Dimitrios Mougiakakos, Martin Böttcher, Livia Perfetto, Natalie Krahmer, Felix Klingelhuber, Monia Pugliese
Publikováno v:
HemaSphere, Vol 7, p e310578d (2023)
Externí odkaz:
https://doaj.org/article/65da723653484a1c9710aed59454bb77
Autor:
Nora Kory, Susanne Grond, Siddhesh S. Kamat, Zhihuan Li, Natalie Krahmer, Chandramohan Chitraju, Ping Zhou, Florian Fröhlich, Ivana Semova, Christer Ejsing, Rudolf Zechner, Benjamin F. Cravatt, Robert V. Farese, Jr., Tobias C. Walther
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 1, Pp 226-235 (2017)
Variations in the gene LDAH (C2ORF43), which encodes lipid droplet-associated hydrolase (LDAH), are among few loci associated with human prostate cancer. Homologs of LDAH have been identified as proteins of lipid droplets (LDs). LDs are cellular orga
Externí odkaz:
https://doaj.org/article/3ec52a4ce7e4467191376e0d18ab2f9f
Autor:
Natalie Krahmer, Matthias Mann
Publikováno v:
Contact, Vol 2 (2019)
Lipid droplets (LDs), important organelles for energy storage and involved in the development of metabolic disorders, are extremely dynamic and interact with many other cellular compartments to orchestrate lipid metabolism. Little is known about how
Externí odkaz:
https://doaj.org/article/9f1a880ac06f4e398908d12c6172f283
Autor:
Imke L. Lemmer, Daniel T. Haas, Nienke Willemsen, Stefan Kotschi, Irmak Toksöz, Ejona Gjika, Sajjad Khani, Maria Rohm, Nick Diercksen, Phong B.H. Nguyen, Michael P. Menden, Desalegn T. Egu, Jens Waschke, Steen Larsen, Tao Ma, Zachary Gerhart-Hines, Stephan Herzig, Kenneth Dyar, Natalie Krahmer, Alexander Bartelt
Muscle function is an important denominator of energy balance and metabolic health. Adapting the proteome to energetic challenges, in response to diet or fasting, is facilitated by programs of proteostasis, but the adaptive role of the ubiquitin-prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07e87d379dc15de8e84ce06a596576cb
https://doi.org/10.1101/2023.04.20.537611
https://doi.org/10.1101/2023.04.20.537611
Autor:
Zhouyi Rong, Hongcheng Mai, Saketh Kapoor, Victor G. Puelles, Jan Czogalla, Julia Schädler, Jessica Vering, Claire Delbridge, Hanno Steinke, Hannah Frenzel, Katja Schmidt, Özüm Sehnaz Caliskan, Jochen Martin Wettengel, Fatma Cherif, Mayar Ali, Zeynep Ilgin Kolabas, Selin Ulukaya, Izabela Horvath, Shan Zhao, Natalie Krahmer, Sabina Tahirovic, Ali Önder Yildirim, Tobias B. Huber, Benjamin Ondruschka, Ingo Bechmann, Gregor Ebert, Ulrike Protzer, Harsharan Singh Bhatia, Farida Hellal, Ali Ertürk
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), has been associated mainly with a range of neurological symptoms, including brain fog and brain tissue loss, raising concerns about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::159d253f4afb7fc6966bf43e2e6c98fa
https://doi.org/10.1101/2023.04.04.535604
https://doi.org/10.1101/2023.04.04.535604
Autor:
Luiza Maria Lutomska, Viktorian Miok, Natalie Krahmer, Ismael González García, Tim Gruber, Ophélia Le Thuc, Cahuê DB Murat, Beata Legutko, Michael Sterr, Gesine Saher, Heiko Lickert, Timo D. Müller, Siegfried Ussar, Matthias H. Tschöp, Dominik Lutter, Cristina García‐Cáceres
Publikováno v:
Glia 70, 2062-2078 (2022)
Glia
Glia
Hypothalamic astrocytes are particularly affected by energy-dense food consumption. How the anatomical location of these glial cells and their spatial molecular distribution in the arcuate nucleus of the hypothalamus (ARC) determine the cellular resp
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2456
Over the recent years, mass spectrometry (MS)-based proteomics has undergone dramatic advances in sample preparation, instrumentation, and computational methods. Here, we describe in detail, how a workflow quantifies global protein phosphorylation in
Autor:
Giorgia Massacci, Veronica Venafra, Sara Latini, Valeria Bica, Giusj Monia Pugliese, Felix Klingelhuber, Natalie Krahmer, Thomas Fischer, Dimitrios Mougiakakos, Martin Boettcher, Livia Perfetto, Francesca Sacco
SummaryInternal tandem duplications (ITDs) in the FLT3 gene are frequently identified and confer a poor prognosis in patient affected by acute myeloid leukemia (AML). The insertion site of the ITDs in FLT3 significantly impacts the sensitivity to tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f44f0b8e756995d2969918634882a9
https://doi.org/10.1101/2022.05.16.492070
https://doi.org/10.1101/2022.05.16.492070