Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Natalia Wegner"'
Autor:
Patrick J Venables, Shauna Culshaw, Bart C. Hamilton, A. Jimmy Ytterberg, Muslima Chowdhury, Ted R. Mikuls, Geoffrey M. Thiele, Elena B. Lugli, Peter Charles, Jan Potempa, Yonghua Guo, Roman A. Zubarev, Anne-Marie Quirke, Benjamin A Fisher, Natalia Wegner
Publikováno v:
Annals of the Rheumatic Diseases; Vol 73
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases
Background: Rheumatoid arthritis (RA) is characterised by autoimmunity to citrullinated proteins, and there is increasing epidemiologic evidence linking Porphyromonas gingivalis to RA. P gingivalis is apparently unique among periodontal pathogens in
Publikováno v:
Arthritis Research & Therapy
Peptidylarginine deiminases (PADs) convert arginine within a peptide (peptidylarginine) into peptidylcitrulline. Citrullination by human PADs is important in normal physiology and inflammation. Porphyromonas gingivalis, a major pathogen in periodonti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6added9d4545df3cc25aa18584f42b
https://ora.ox.ac.uk/objects/uuid:182d7158-b37f-48ac-8bfe-418a8348516e
https://ora.ox.ac.uk/objects/uuid:182d7158-b37f-48ac-8bfe-418a8348516e
Autor:
Andrew J Kinloch, Karin Lundberg, Robin Wait, Vivianne Malmström, Ngee Han Lim, Natalia Wegner, Tore Saxne, Patrick J Venables
Publikováno v:
Rheumatology. 47:ii52-ii59
Autor:
Sarang Chitale, Alex J. MacGregor, Deborah Symmons, Deborah P M Symmons, Cristina Estrach, Stephanie Ling, Louise K. Mercer, Mark Lunt, Kimme L. Hyrich, Kath D. Watson, James N. Galloway, Saba Alzabin, Nicola J Goodson, William G Dixon, Rebecca Davies, Jane Skinner, David A. Bell, Sarah R. Dawson, Elizabeth Wilson, Wenjia Wang, Geoffrey R. Guile, Tim D. Spector, Lillian Barran, Robert J. Moots, Jonathan Packham, Natalia Wegner, Brent Richards, Derek L. Mattey, Patrick J Venables, Andrew J Kinloch, Aedin Cassidy, Ewa Cairns, Emma L. Healey, Diane Bunn, Suzanne M M Verstappen, Susan J. Fairweather-Tait, William Brintnell, David Sharpley, David G. I. Scott
Publikováno v:
Rheumatology. 50:iii37-iii39
Autor:
Andrew J. Kinloch, Saba Alzabin, Natalia Wegner, William Brintnell, Elizabeth Wilson, Lillian Barra, David A. Bell, Ewa Cairns, Patrick J. Venables
Publikováno v:
Bone and Joint Institute
Autor:
Saba Alzabin, Andrew J Kinloch, Natalia Wegner, William Brintnell, Lillian Barra, Patrick J Venables, David A. Bell, Elizabeth Wilson, Ewa Cairns
Publikováno v:
ResearcherID
Bone and Joint Institute
Bone and Joint Institute
Objective To examine the hypothesis that the subset of rheumatoid arthritis (RA) characterized by antibodies to citrullinated α-enolase is mediated by Porphyromonas gingivalis enolase in the context of DR4 alleles. Methods Recombinant human α-enola
Publikováno v:
Nature reviews. Rheumatology. 6(12)
Antibodies to citrullinated enolase define a subset of rheumatoid arthritis (RA) associated with smoking and DR4 alleles. In this Perspectives article, the authors review epidemiological and genetic links between periodontitis (a disease in whichPorp
Publikováno v:
Nature reviews. Rheumatology. 6(12)
Autoimmunity in rheumatoid arthritis (RA) is characterized by an antibody response to citrullinated proteins. Two of the risk factors for RA-HLA-DRB1 shared epitope alleles and smoking-are also associated with periodontitis, which is largely, but not
Autor:
Marc Feldmann, Vivianne Malmström, Benjamin A Fisher, Patrick J Venables, Karin Lundberg, Natalia Wegner, Andrew J Kinloch
Publikováno v:
ResearcherID
Rheumatoid arthritis (RA) is now clearly a true autoimmune disease with accumulating evidence of pathogenic disease-specific autoimmunity to citrullinated proteins. Citrullination, also termed deimination, is a modification of arginine side chains ca
Autor:
Robin Wait, Ngee Han Lim, Vivianne Malmström, Karin Lundberg, Tore Saxne, Albert J.W. Zendman, Patrick J Venables, Natalia Wegner, Andrew J Kinloch
Publikováno v:
Arthritis and rheumatism. 58(8)
OBJECTIVE: To examine synovial fluid as a site for generating citrullinated antigens, including the candidate autoantigen citrullinated alpha-enolase, in rheumatoid arthritis (RA). METHODS: Synovial fluid was obtained from 20 patients with RA, 20 pat