Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Natalia Vereshchagina"'
Autor:
Jun-Yi Zhu, Natalia Vereshchagina, Vrinda Sreekumar, Lena F Burbulla, Ana C Costa, Katharina J Daub, Dirk Woitalla, L Miguel Martins, Rejko Krüger, Tobias M Rasse
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83714 (2013)
Mortalin is an essential component of the molecular machinery that imports nuclear-encoded proteins into mitochondria, assists in their folding, and protects against damage upon accumulation of dysfunctional, unfolded proteins in aging mitochondria.
Externí odkaz:
https://doaj.org/article/1f3bb5a580b445a3bc2ee4f2731508f0
Autor:
Ann-Christin Krahl, Thomas R. Jahn, Nina M. Dräger, Shabab B. Hannan, Christopher J. H. Elliott, Yulong Fu, Jun-yi Zhu, Natalia Vereshchagina, Zhe Han, Tobias M. Rasse
Publikováno v:
Autophagy. 17:3160-3174
We investigated in larval and adult Drosophila models whether loss of the mitochondrial chaperone Hsc70-5 is sufficient to cause pathological alterations commonly observed in Parkinson disease. At affected larval neuromuscular junctions, no effects o
Autor:
Jun-Yi, Zhu, Shabab B, Hannan, Nina M, Dräger, Natalia, Vereshchagina, Ann-Christin, Krahl, Yulong, Fu, Christopher J H, Elliott, Zhe, Han, Thomas R, Jahn, Tobias M, Rasse
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
We investigated in larval and adult Drosophila models whether loss of the mitochondrial chaperone Hsc70-5 is sufficient to cause pathological alterations commonly observed in Parkinson disease. At affected larval neuromuscular junctions, no effects o
Autor:
Tobias M. Rasse, Thomas R. Jahn, Jun-yi Zhu, Shabab B. Hannan, Yulong Fu, Nina Draeger, Christopher J. H. Elliott, Ann-Christin Krahl, Zhe Han, Natalia Vereshchagina
We investigate in larval and adult Drosophila models whether loss of the mitochondrial chaperone Hsc70-5/mortalin is sufficient to cause pathological alterations commonly observed in Parkinson disease. At affected larval neuromuscular junctions, no e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::785a102f76d4a41bf7727dd368e233dd
https://doi.org/10.1101/2020.09.17.302141
https://doi.org/10.1101/2020.09.17.302141
Inappropriate regulation of the PI3-kinase/PTEN/Akt kinase-signalling cassette, a key downstream target of insulin/insulin-like growth factor signalling (IIS), is associated with several major human diseases such as diabetes, obesity and cancer. In D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f18ecc572088d876f72c9cf3506b59
https://ora.ox.ac.uk/objects/uuid:209b4470-040e-4281-b9d6-ac758a6e4a46
https://ora.ox.ac.uk/objects/uuid:209b4470-040e-4281-b9d6-ac758a6e4a46
Autor:
David Meredith, Bruno Reynolds, Natalia Vereshchagina, Deborah C.I. Goberdhan, C. A. R. Boyd, Clive Wilson
The PI3K (phosphoinositide 3-kinase)/Akt (also called protein kinase B) signalling cassette plays a central role in the response to growth factors, particularly insulin-like molecules, and its misregulation is a characteristic feature of diabetes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6af3981f91c91d9289a7735271d8c1
https://doi.org/10.1042/bst0350219
https://doi.org/10.1042/bst0350219
Autor:
Clive Wilson, Natalia Vereshchagina
Publikováno v:
Development. 133:4731-4735
The insulin/insulin-like growth factor signalling (IIS) cascade performs a broad range of evolutionarily conserved functions, including the regulation of growth, developmental timing and lifespan, and the control of sugar, protein and lipid metabolis
Autor:
Luke Alphey, Emese Vissi, Daimark Bennett, Sascha Gross, Helen White-Cooper, Natalia Vereshchagina, Balazs Szoor, Jasmin Kirchner
Reversible phosphorylation of myosin regulatory light chain (MRLC) is a key regulatory mechanism controlling myosin activity and thus regulating the actin/myosin cytoskeleton. We show that Drosophila PP1beta, a specific isoform of serine/threonine pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f97588b94b976a4624ef78b9a6f5ff
https://europepmc.org/articles/PMC519135/
https://europepmc.org/articles/PMC519135/
Autor:
Natalia, Vereshchagina, Daimark, Bennett, Balzs, Szor, Jasmin, Kirchner, Sascha, Gross, Emese, Vissi, Helen, White-Cooper, Luke, Alphey
Publikováno v:
Molecular Biology of the Cell; October 2004, Vol. 15 Issue: 10 p4395-405, 11p
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
We have identified two proteins that bind with high specificity to type 1 serine/threonine protein phosphatase (PP1) and have exploited their inhibitory properties to develop an efficient and flexible strategy for conditional inactivation of PP1 in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a9ad0163afdd817f5ff89e23743fe4
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037516890&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037516890&partnerID=MN8TOARS