Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Natalia VanDuyn"'
Autor:
Wei Li, Holly J Garringer, Charles B Goodwin, Briana Richine, Anthony Acton, Natalia VanDuyn, Barry B Muhoberac, Jose Irimia-Dominguez, Rebecca J Chan, Munro Peacock, Richard Nass, Bernardino Ghetti, Ruben Vidal
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117435 (2015)
Ferritin, a 24-mer heteropolymer of heavy (H) and light (L) subunits, is the main cellular iron storage protein and plays a pivotal role in iron homeostasis by modulating free iron levels thus reducing radical-mediated damage. The H subunit has ferro
Externí odkaz:
https://doaj.org/article/6126ab41a1d3406c997dd958c4f8510c
Autor:
Richard Nass, Natalia VanDuyn
Publikováno v:
Journal of Neurochemistry. 128:962-974
Parkinson’s disease (PD) is the most prevalent neurodegenerative motor disorder worldwide, and results in the progressive loss of dopamine (DA) neurons in the substantia nigra pars compacta. Gene-environment interactions are believed to play a sign
Autor:
Martina Rudgalvyte, Liisa Heikkinen, Merja Lakso, Juhani Peltonen, Richard Nass, Garry Wong, Vuokko Aarnio, Natalia VanDuyn
Publikováno v:
Toxicology Letters. 222:189-196
Methylmercury (MeHg) is a persistent environmental and dietary contaminant that causes serious adverse developmental and physiologic effects at multiple cellular levels. In order to understand more fully the consequences of MeHg exposure at the molec
Publikováno v:
NeuroToxicology. 38:51-60
Exposure to high levels of manganese (Mn) results in a neurological condition termed manganism, which is characterized by oxidative stress, abnormal dopamine (DA) signaling, and cell death. Epidemiological evidence suggests correlations with occupati
C. elegans as a Genetic Model System to Identify Parkinson's Disease- Associated Therapeutic Targets
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 11:957-964
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms and the selective loss of dopaminergic neurons. The etiology of idiopathic PD is likely a combination of genetic and environmental factors. Despite
Autor:
Natalia VanDuyn, Jennifer LeVora, Jason M. Unrine, Shaoyu Zhou, Richard Nass, Raja S. Settivari
Publikováno v:
Journal of Neurochemistry. 124:147-157
Aluminum (Al(3+)) is the most prevalent metal in the earth's crust and is a known human neurotoxicant. Al(3+) has been shown to accumulate in the substantia nigra of patients with Parkinson's disease (PD), and epidemiological studies suggest correlat
Autor:
Matthew Mort, Yunlong Liu, Howard J. Edenberg, David Neil Cooper, Sean D. Mooney, Natalia VanDuyn, Jeremy R. Sanford, Xin Wang
Publikováno v:
Genome Research. 19:381-394
Metazoan genes are encrypted with at least two superimposed codes: the genetic code to specify the primary structure of proteins and the splicing code to expand their proteomic output via alternative splicing. Here, we define the specificity of a cen
Autor:
Munro Peacock, Briana M. Richine, Natalia VanDuyn, Rebecca J. Chan, Bernardino Ghetti, Anthony J. Acton, Ruben Vidal, Barry B. Muhoberac, Charles B. Goodwin, Richard Nass, Holly J. Garringer, Wei Li, Jose Irimia-Dominguez
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117435 (2015)
PLoS ONE
PLoS ONE
Ferritin, a 24-mer heteropolymer of heavy (H) and light (L) subunits, is the main cellular iron storage protein and plays a pivotal role in iron homeostasis by modulating free iron levels thus reducing radical-mediated damage. The H subunit has ferro
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 118(2)
Methylmercury (MeHg) exposure from occupational, environmental, and food sources is a significant threat to public health. MeHg poisonings in adults may result in severe psychological and neurological deficits, and in utero exposures can confer embry