Impact of obesity and roux‐en‐Y gastric bypass on the pharmacokinetics of (R)‐ and (S)‐omeprazole and intragastric pH

Autor: Leandro F. Pippa, Valvanera Vozmediano, Lieke Mitrov‐Winkelmolen, Daan Touw, Amira Soliman, Rodrigo Cristofoletti, Wilson Salgado Junior, Natalia Valadares de Moraes

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 9, Pp 1528-1541 (2024)

Abstract This study employed physiologically‐based pharmacokinetic–pharmacodynamics (PBPK/PD) modeling to predict the effect of obesity and gastric bypass surgery on the pharmacokinetics and intragastric pH following omeprazole treatment. The sim

Externí odkaz: https://doaj.org/article/5a65cde4a533494db54a046517658249

Influência do diabetes descompensado na disposição cinética, metabolismo e farmacocinética-farmacodinâmica dos enantiômeros do tramadol em pacientes com dor neuropática

Autor: Natalia Valadares de Moraes

Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

O tramadol é um analgésico de ação central eficaz na atenuação de dores agudas e crônicas, entre elas a dor neuropática em pacientes diabéticos. Encontra-se disponível na clínica como mistura de (+)-tramadol e (-)-tramadol. O tramadol é m

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/60/60134/tde-12122011-210534/

Recycled household ash in rice paddies of Bangladesh for sustainable production of rice without altering grain arsenic and cadmium

Autor: Yogesh Gupta, Mahmud Hossain, M. Rafiqul Islam, Md. Moyeed Hasan Talukder, Md. Atiqur Rahman Khokon, Mohammad Mahir Uddin, Humayun Kabir, Manus Carey, Kathryn Ralphs, Natalia Valadares de Moraes, Andrew A. Meharg, Caroline Meharg

Publikováno v: Gupta, Y, Hossain, M, Islam, M R, Talukder, M M H, Khokon, M A R, Uddin, M M, Kabir, H, Carey, M, Ralphs, K, Valadares de Moraes, N, Meharg, A A & Meharg, C 2023, ' Recycled household ash in rice paddies of Bangladesh for sustainable production of rice without altering grain arsenic and cadmium ', Exposure and Health . https://doi.org/10.1007/s12403-023-00539-y

In Bangladesh most agronomic biomass (straw, husk, dried dung) is burnt for domestic cooking use. Consequently, the soil is continuously stripped of mineral nutrients and carbon (C) substrate. Here we investigate if recycling of household ash (ash) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9014602fcb713f2ecb5448fdcda84a65
https://pure.qub.ac.uk/en/publications/4b22a506-9e1f-4016-bcb2-d8b36a20875b

Influência do diabetes descompensado na disposição cinética, metabolismo e farmacocinética-farmacodinâmica dos enantiômeros do tramadol em pacientes com dor neuropática

Autor: Natalia Valadares de Moraes

Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

O tramadol é um analgésico de ação central eficaz na atenuação de dores agudas e crônicas, entre elas a dor neuropática em pacientes diabéticos. Encontra-se disponível na clínica como mistura de (+)-tramadol e (-)-tramadol. O tramadol é m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36b5669145ae95022a10dcc7e6312d9
https://doi.org/10.11606/t.60.2011.tde-12122011-210534

Pharmacokinetics of Carboplatin in Combination with Low-Dose Cyclophosphamide in Female Dogs with Mammary Carcinoma

Autor: Marília Carneiro Machado, Priscila Akemi Yamamoto, Leandro Francisco Pippa, Natália Valadares de Moraes, Fabiane Maria Fernandes Neves, Ricardo Dias Portela, Stella Maria Barrouin-Melo, Anna Hielm-Björkman, Ana Leonor Pardo Campos Godoy, Alessandra Estrela-Lima

Publikováno v: Animals, Vol 12, Iss 22, p 3109 (2022)

This prospective study aimed to evaluate the effect of metronomic cyclophosphamide on carboplatin’s tolerability, efficacy, and pharmacokinetics in dogs with mammary carcinoma. Sixteen female dogs with mammary carcinoma were divided into groups: 30

Externí odkaz: https://doaj.org/article/fa2be0d246804193abc2f835f5da4f68