Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Natalia V. Gounko"'
Autor:
Dorien Vandael, Katlijn Vints, Pieter Baatsen, Małgorzata A. Śliwińska, Sergio Gabarre, Lies De Groef, Lieve Moons, Vasily Rybakin, Natalia V. Gounko
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The neuropeptide corticotropin-releasing factor (CRF) exerts a pivotal role in modulating neuronal activity in the mammalian brain. The effects of CRF exhibit notable variations, depending on factors such as duration of exposure, concentrati
Externí odkaz:
https://doaj.org/article/f595abeb016948aea2354deb0f1a17dc
Autor:
Dorien Vandael, Keimpe Wierda, Katlijn Vints, Pieter Baatsen, Lies De Groef, Lieve Moons, Vasily Rybakin, Natalia V. Gounko
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Biological responses to stress are complex and highly conserved. Corticotropin-releasing factor (CRF) plays a central role in regulating these lifesaving physiological responses to stress. We show that, in mice, CRF rapidly changes Schaffer
Externí odkaz:
https://doaj.org/article/2e96ad286fab419aba2058c80009d536
Autor:
Sergio Gabarre, Frank Vernaillen, Pieter Baatsen, Katlijn Vints, Christopher Cawthorne, Steven Boeynaems, Emiel Michiels, Dorien Vandael, Natalia V. Gounko, Sebastian Munck
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Array tomography (AT) is a high-resolution imaging method to resolve fine details at the organelle level and has the advantage that it can provide 3D volumes to show the tissue context. AT can be carried out in a correlative way,
Externí odkaz:
https://doaj.org/article/c9f3ae87e1b64782be311c18eb494bac
Autor:
Nuno Apóstolo, Samuel N. Smukowski, Jeroen Vanderlinden, Giuseppe Condomitti, Vasily Rybakin, Jolijn ten Bos, Laura Trobiani, Sybren Portegies, Kristel M. Vennekens, Natalia V. Gounko, Davide Comoletti, Keimpe D. Wierda, Jeffrey N. Savas, Joris de Wit
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Mossy fiber synapses are key in CA3 microcircuit function. Here, the authors profile the mossy fiber synapse proteome and cell-surface interactome. They uncover a diverse repertoire of cell-surface proteins and identify the receptor IgSF8 as a regula
Externí odkaz:
https://doaj.org/article/73f057183b374a89915c293d2ed3556b
Autor:
Pieter Baatsen, Sergio Gabarre, Katlijn Vints, Rosanne Wouters, Dorien Vandael, Rose Goodchild, Sebastian Munck, Natalia V. Gounko
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Life science research often needs to define where molecules are located within the complex environment of a cell or tissue. Genetically encoded fluorescent proteins and or fluorescence affinity-labeling are the go-to methods. Although recent fluoresc
Externí odkaz:
https://doaj.org/article/3468df905ce2402a9259823135d771b7
Autor:
Karen Rosier, Molly T. McDevitt, Joél Smet, Brendan J. Floyd, Maxime Verschoore, Maria J. Marcaida, Craig A. Bingman, Irma Lemmens, Matteo Dal Peraro, Jan Tavernier, Benjamin F. Cravatt, Natalia V. Gounko, Katlijn Vints, Yenthe Monnens, Kritika Bhalla, Laetitia Aerts, Edrees H. Rashan, Arnaud V. Vanlander, Rudy Van Coster, Luc Régal, David J. Pagliarini, John W.M. Creemers
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103460- (2021)
Summary: Deficiency of the serine hydrolase prolyl endopeptidase-like (PREPL) causes a recessive metabolic disorder characterized by neonatal hypotonia, feeding difficulties, and growth hormone deficiency. The pathophysiology of PREPL deficiency and
Externí odkaz:
https://doaj.org/article/a2916c2ecc194c18bb66fc5774a5e60f
Autor:
Tijs Vandoorne, Koen Veys, Wenting Guo, Adria Sicart, Katlijn Vints, Ann Swijsen, Matthieu Moisse, Guy Eelen, Natalia V. Gounko, Laura Fumagalli, Raheem Fazal, Christine Germeys, Annelies Quaegebeur, Sarah-Maria Fendt, Peter Carmeliet, Catherine Verfaillie, Philip Van Damme, Bart Ghesquière, Katrien De Bock, Ludo Van Den Bosch
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
While energy metabolism has been repeatedly linked to ALS, motor neuron metabolism remains poorly studied. Here, authors show that human iPSCs rewire specific metabolic routes when they differentiate into functional motor neurons and that ALS-causing
Externí odkaz:
https://doaj.org/article/fa80c26ad33443938150866628a1b0dd
Autor:
Victor Briz, Leonardo Restivo, Emanuela Pasciuto, Konrad Juczewski, Valentina Mercaldo, Adrian C. Lo, Pieter Baatsen, Natalia V. Gounko, Antonella Borreca, Tiziana Girardi, Rossella Luca, Julie Nys, Rogier B. Poorthuis, Huibert D. Mansvelder, Gilberto Fisone, Martine Ammassari-Teule, Lutgarde Arckens, Patrik Krieger, Rhiannon Meredith, Claudia Bagni
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Brain cytoplasmic (BC1) RNA is a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety. Here, the authors show that in the cortex, BC1 RNA is required for sensory deprivation-induced structural plasticity of dendri
Externí odkaz:
https://doaj.org/article/c904b79eda0c41d194c02e95b2cd0dea
Publikováno v:
Molecular Metabolism, Vol 4, Iss 3, Pp 246-252 (2015)
Objective: Although both insulin and glucagon are intimately involved in the regulation of glucose homeostasis, the intrinsic control of glucagon secretion, including the biogenesis and exocytosis of glucagon-containing granules, is far less understo
Externí odkaz:
https://doaj.org/article/1370223d2e114ee9b608a2cafa9da5d6
Autor:
Adekunle T. Bademosi, Marianna Decet, Sabine Kuenen, Carles Calatayud, Jef Swerts, Sandra F. Gallego, Nils Schoovaerts, Spyridoula Karamanou, Nikolaos Louros, Ella Martin, Jean-Baptiste Sibarita, Katlijn Vints, Natalia V. Gounko, Frédéric A. Meunier, Anastassios Economou, Wim Versées, Frederic Rousseau, Joost Schymkowitz, Sandra-F. Soukup, Patrik Verstreken
Publikováno v:
Neuron. 111:1402-1422.e13
Neuronal activity causes use-dependent decline in protein function. However, it is unclear how this is coupled to local quality control mechanisms. We show in Drosophila that the endocytic protein Endophilin-A (EndoA) connects activity-induced calciu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0810cbd9c9d27c4f1798bb2adf77be17
https://doi.org/10.1016/j.neuron.2023.02.001
https://doi.org/10.1016/j.neuron.2023.02.001