Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Natalia V. Bogatcheva"'
Autor:
Hongyan Lu, Stephanie Merfeld-Clauss, Yameena Jawed, Keith L. March, Michael E. Coleman, Natalia V. Bogatcheva
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
We have shown previously that adipose stromal cell (ASC)-derived conditioned media (CM) limited lung injury, endothelial barrier dysfunction, and apoptosis. Here, we used endothelial hyperpermeability and apoptosis assays to investigate how concentra
Externí odkaz:
https://doaj.org/article/deb7baf100c04313950ce5aaee2f8b75
Concentrated Secretome of Adipose Stromal Cells Limits Influenza A Virus-Induced Lung Injury in Mice
Publikováno v:
Cells, Vol 10, Iss 4, p 720 (2021)
Despite vaccination and antivirals, influenza remains a communicable disease of high burden, with limited therapeutic options available to patients that develop complications. Here, we report the development and preclinical characterization of Adipos
Externí odkaz:
https://doaj.org/article/d15217308b84466a8ea0a8f9935cc715
Autor:
Hongyan Lu, Todd Cook, Christophe Poirier, Stephanie Merfeld-Clauss, Irina Petrache, Keith L. March, Natalia V. Bogatcheva Ph.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Transplantation of mesenchymal stromal cells (MSCs) has been shown to effectively prevent lung injury in several preclinical models of acute respiratory distress syndrome (ARDS). Since MSC therapy is tested in clinical trials for ARDS, there is an in
Externí odkaz:
https://doaj.org/article/3561acae2c574476af2a9ded24fada2c
Publikováno v:
TP94. TP094 DISCOVERIES IN BACTERIAL AND VIRAL PNEUMONIA PATHOGENESIS.
Autor:
Hongyan Lu, Jacob Saliba, Sarvesh Chelvanambi, Natalia V. Bogatcheva, Keith L. March, Christophe Poirier, Matthias Clauss
Publikováno v:
Molecular Therapy
Influenza A virus (IAV) remains a major worldwide health threat, especially to high-risk populations, including the young and elderly. There is an unmet clinical need for therapy that will protect the lungs from damage caused by lower respiratory inf
Publikováno v:
Biochemistry. Biokhimiia. 84(11)
Mesenchymal stromal cell (MSCs) represent a class of biologics with the prospects for employment as immunomodulatory, tissue-protective, and regenerative therapeutics. In parallel with cellular therapy, cell-free therapy based on MSC-secreted bioacti
Autor:
Irina Petrache, Christophe Poirier, Todd G. Cook, Stephanie Merfeld-Clauss, Keith L. March, Natalia V. Bogatcheva, Hongyan Lu
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Transplantation of mesenchymal stromal cells (MSCs) has been shown to effectively prevent lung injury in several preclinical models of acute respiratory distress syndrome (ARDS). Since MSC therapy is tested in clinical trials for ARDS, there is an in
Publikováno v:
C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION.
Autor:
Paul Jolicoeur, Matthias Clauss, Nathan J. Alves, Homer L. Twigg, Hongyan Lu, Manal Mohamed Saber, Norbert Weissmann, Bernhard Maier, Navneet K. Dhillon, Sarvesh Chelvanambi, Qigui Yu, Noelle Dahl, Patricia Smith, Stuti Agarwal, Farooq Syed, Wei Li, Natalia V. Bogatcheva, Mariola Bednorz, Richard B. Day
Publikováno v:
American journal of respiratory cell and molecular biology. 60(3)
It remains a mystery why HIV-associated end-organ pathologies persist in the era of combined antiretroviral therapy (ART). One possible mechanism is the continued production of HIV-encoded proteins in latently HIV-infected T cells and macrophages. Th