Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Natalia Tsymbalyuk"'
Autor:
Bolanle M. Famakin, Orest Tsymbalyuk, Natalia Tsymbalyuk, Svetlana Ivanova, Seung Kyoon Woo, Min Seong Kwon, Volodymyr Gerzanich, J. Marc Simard
Publikováno v:
Neurology Research International, Vol 2020 (2020)
Limited, and underutilized, therapeutic options for acute stroke require new approaches to treatment. One such potential approach involves better understanding of innate immune response to brain injury such as acute focal cerebral ischemia. This incl
Externí odkaz:
https://doaj.org/article/5c28bfe1c460459795d7e9974e458716
Autor:
Seung Kyoon, Woo, Natalia, Tsymbalyuk, Orest, Tsymbalyuk, Svetlana, Ivanova, Volodymyr, Gerzanich, J Marc, Simard
Publikováno v:
Neurosci Lett
BACKGROUND. Preclinical and emerging clinical data show that glibenclamide reduces space occupying edema and brain swelling following cerebral ischemia. Glibenclamide is a potent inhibitor of numerous sulfonylurea receptor (SUR)-regulated channels, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::173a7294368e564dd4afef812c103e25
https://pubmed.ncbi.nlm.nih.gov/31899311
https://pubmed.ncbi.nlm.nih.gov/31899311
Autor:
Orest Tsymbalyuk, Volodymyr Gerzanich, Svetlana Ivanova, Natalia Tsymbalyuk, Seung Kyoon Woo, J. Marc Simard
Publikováno v:
Neuroscience Letters. 718:134729
Background Preclinical and emerging clinical data show that glibenclamide reduces space occupying edema and brain swelling following cerebral ischemia. Glibenclamide is a potent inhibitor of numerous sulfonylurea receptor (SUR)-regulated channels, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5556b4556d8bc4178cc7217d17273682
https://doi.org/10.1016/j.neulet.2019.134729
https://doi.org/10.1016/j.neulet.2019.134729
Autor:
J. Marc Simard, Bolanle M. Famakin, Svetlana Ivanova, Cigdem Tosun, Natalia Tsymbalyuk, Rudy J. Castellani, Volodymyr Gerzanich, Min Seong Kwon, Rupal I. Mehta
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 74:835-849
The nonselective monovalent cation channel transient receptor potential melastatin 4 (Trpm4) is transcriptionally upregulated in neural and vascular cells in animal models of brain infarction. It associates with sulfonylurea receptor 1 (Sur1) to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453317ab2c3202beb1830be9b0d7fbab
https://doi.org/10.1097/nen.0000000000000223
https://doi.org/10.1097/nen.0000000000000223
Publikováno v:
Journal of neuropathology and experimental neurology. 76(10)
In nutrient restricted environments, the yeast endosulfines Igo1/2 are activated via TORC1 inhibition and function critically to initiate and coordinate the cellular stress response that promotes survival. We examined expression of αEnsa, the mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ba5f9c24017675f487d6e004be6c67
https://pubmed.ncbi.nlm.nih.gov/28922851
https://pubmed.ncbi.nlm.nih.gov/28922851
Autor:
Natalia Tsymbalyuk, Seung Kyoon Woo, Svetlana Ivanova, Ryan Lee, Oksana Voloshyn, J. Marc Simard, Volodymyr Gerzanich, Vladimir V. Yurovsky
Publikováno v:
Translational Stroke Research
Glibenclamide improves outcomes in rat models of stroke, with treatment as late as 6 h after onset of ischemia shown to be beneficial. Because the molecular target of glibenclamide, the sulfonylurea receptor 1 (Sur1)-regulated NCCa-ATP channel, is up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984ff54e03037d198a8edb8ea8a791a5
http://europepmc.org/articles/PMC3362710
http://europepmc.org/articles/PMC3362710
Autor:
Natalia Tsymbalyuk, J. Marc Simard, Volodymyr Gerzanich, Vladimir V. Yurovsky, Svetlana Ivanova, Orest Tsymbalyuk
Publikováno v:
Stroke. 41:531-537
Background and Purpose— Treating patients with malignant cerebral infarctions remains a major unsolved problem in medicine. Decompressive craniectomy (DC) improves the bleak outlook but is suboptimal. Using a rat model of severe ischemia/reperfusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd396bf6b9e30965e3f61f6eadf26fec
https://doi.org/10.1161/strokeaha.109.572644
https://doi.org/10.1161/strokeaha.109.572644
Autor:
Vladimir V. Yurovsky, J. Marc Simard, Volodymyr Gerzanich, Svetlana Ivanova, Ludmila Melnichenko, Natalia Tsymbalyuk
Background and Purpose— Ischemia/hypoxia induces de novo expression of the sulfonylurea receptor 1-regulated NC(Ca-ATP) channel. In rodent models of ischemic stroke, early postevent administration of the sulfonylurea, glibenclamide, is highly effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0391a0010f85376f79f2eeecd9affdd
https://europepmc.org/articles/PMC2744391/
https://europepmc.org/articles/PMC2744391/
