Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Natalia Tretyakova"'
Publikováno v:
Toxics, Vol 9, Iss 10, p 247 (2021)
1,3-Butadiene (BD) is a common environmental and industrial chemical widely used in plastic and rubber manufacturing and also present in cigarette smoke and automobile exhaust. BD is classified as a known human carcinogen based on evidence of carcino
Externí odkaz:
https://doaj.org/article/59ee0b9d77924d828d0f4a8d27dcaa83
Autor:
Joel Hrit, Leeanne Goodrich, Cheng Li, Bang-An Wang, Ji Nie, Xiaolong Cui, Elizabeth Allene Martin, Eric Simental, Jenna Fernandez, Monica Yun Liu, Joseph R Nery, Rosa Castanon, Rahul M Kohli, Natalia Tretyakova, Chuan He, Joseph R Ecker, Mary Goll, Barbara Panning
Publikováno v:
eLife, Vol 7 (2018)
TET enzymes convert 5-methylcytosine to 5-hydroxymethylcytosine and higher oxidized derivatives. TETs stably associate with and are post-translationally modified by the nutrient-sensing enzyme OGT, suggesting a connection between metabolism and the e
Externí odkaz:
https://doaj.org/article/a02f6ba8c3d5438d937c2000b1fe0c50
Autor:
Lisa N. Chesner, Amanda Degner, Dewakar Sangaraju, Shira Yomtoubian, Susith Wickramaratne, Bhaskar Malayappan, Natalia Tretyakova, Colin Campbell
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 5, p 1086 (2017)
Xenobiotic-induced interstrand DNA–DNA cross-links (ICL) interfere with transcription and replication and can be converted to toxic DNA double strand breaks. In this work, we investigated cellular responses to 1,4-bis-(guan-7-yl)-2,3-butanediol (bi
Externí odkaz:
https://doaj.org/article/d28908a74a2646839753a2cae78c2618
Autor:
Natalia Tretyakova, Loïc Le Marchand, Daniel O. Stram, Maarit Tiirikainen, Sungshim L. Park, Amanda Esades, Srikanth Kotapati, Yesha M. Patel, Emily J. Boldry
Background: 1,3-Butadiene (BD) is an important carcinogen in tobacco smoke that undergoes metabolic activation to DNA-reactive epoxides. These species can be detoxified via glutathione conjugation and excreted in urine as the corresponding N-acetylcy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a07abec4c556008d55c31acf4dd124
https://doi.org/10.1158/1055-9965.c.6515661.v1
https://doi.org/10.1158/1055-9965.c.6515661.v1
Autor:
Loïc Le Marchand, Natalia Tretyakova, Sharon E. Murphy, Maarit Tiirikainen, Lynne R. Wilkens, Srikanth Kotapati, Sungshim Lani Park
Supplemental Table 1. Spearman's partial correlations (r)a between 1,3 butadiene urinary metabolites and nicotine equivalents.Supplemental Table 2. Geometric means (95% Confidence Limits) for the 1,3 butadiene metabolite, MHBMA (ng/mg Cr),stratified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4daffe2a50a8dcc98d6ba308291d0cf4
https://doi.org/10.1158/1055-9965.22435761
https://doi.org/10.1158/1055-9965.22435761
Autor:
Loïc Le Marchand, Natalia Tretyakova, Sharon E. Murphy, Maarit Tiirikainen, Lynne R. Wilkens, Srikanth Kotapati, Sungshim Lani Park
Background: We hypothesize that the differences in lung cancer risk in Native Hawaiians, whites, and Japanese Americans may, in part, be due to variation in the metabolism of 1,3-butadiene, one of the most abundant carcinogens in cigarette smoke.Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d767cb874f3db4ce45a3bcaa762fca
https://doi.org/10.1158/1055-9965.c.6515088
https://doi.org/10.1158/1055-9965.c.6515088
Autor:
Natalia Tretyakova, Loïc Le Marchand, Daniel O. Stram, Maarit Tiirikainen, Sungshim L. Park, Amanda Esades, Srikanth Kotapati, Yesha M. Patel, Emily J. Boldry
Experimental details Supplement S-1. Details of HPLC-ESI-MS/MS methodology. Tables Supplementary Table 1. Geometric means (95% confidence limits) for urinary MHBMA and DHBMA by race/ethnicity and sex. Values are given in ng/mg creatinine (Cr). Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f765ae70e6c29147c2e489eeba1464
https://doi.org/10.1158/1055-9965.22436994.v1
https://doi.org/10.1158/1055-9965.22436994.v1
Autor:
Leona D. Samson, Forest M. White, Michael T. Hemann, Jacqueline A. Lees, Natalia Tretyakova, Yimin Chen, Amanda Vargas, Kelly Barford, Edvinas Cerniauskas, Dewakar Sangaraju, Patrizia Mazzucato, Zachary D. Nagel, Monica Stanciu, Christian J. Braun, José L. McFaline-Figueroa
Supplementary Figures S1-S14. p53 levels in p53 knockdown GBM cells (S1); TMZR3 cells obtained from a p53 deficient background display increased ploidy (S2); H2AX activation in temozolomide treated parental and TMZR3 GBM cells (S3); In-cell Host cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d61595daab9ce727fba79788a9a5d5e
https://doi.org/10.1158/0008-5472.22405706.v1
https://doi.org/10.1158/0008-5472.22405706.v1
Autor:
Leona D. Samson, Forest M. White, Michael T. Hemann, Jacqueline A. Lees, Natalia Tretyakova, Yimin Chen, Amanda Vargas, Kelly Barford, Edvinas Cerniauskas, Dewakar Sangaraju, Patrizia Mazzucato, Zachary D. Nagel, Monica Stanciu, Christian J. Braun, José L. McFaline-Figueroa
Supplementary Tables S1-S2. O6-methylguanine adducts levels in parental and TMZR3 GBM cells 3 hours post-TMZ exposure (S1); shRNA constructs used in this study (S2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03141e6265910024dfffd4d88b95bfac
https://doi.org/10.1158/0008-5472.22405700.v1
https://doi.org/10.1158/0008-5472.22405700.v1
1,3-Butadiene (BD) is an important industrial and environmental chemical classified as a human carcinogen based on epidemiologic studies in occupationally exposed workers and animal studies in laboratory rats and mice. BD is metabolically activated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404ff08b6f6e6853dd8d2c65d486d911
https://doi.org/10.1158/0008-5472.c.6499391.v1
https://doi.org/10.1158/0008-5472.c.6499391.v1