Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Natalia Teruel"'
Autor:
Carlos A Rodríguez-Salazar, Sarah van Tol, Olivier Mailhot, Maria Gonzalez-Orozco, Gabriel T Galdino, Abbey N Warren, Natalia Teruel, Padmanava Behera, Kazi Sabrina Afreen, Lihong Zhang, Terry L Juelich, Jennifer K Smith, María Inés Zylber, Alexander N Freiberg, Rafael J Najmanovich, Maria I Giraldo, Ricardo Rajsbaum
Publikováno v:
PLoS Biology, Vol 22, Iss 2, p e3002544 (2024)
Ebolavirus (EBOV) belongs to a family of highly pathogenic viruses that cause severe hemorrhagic fever in humans. EBOV replication requires the activity of the viral polymerase complex, which includes the cofactor and Interferon antagonist VP35. We p
Externí odkaz:
https://doaj.org/article/99a4e0e8910746299e1402b8c51819c3
The recently reported Omicron (B.1.1.529) SARS-CoV-2 variant has a large number of mutations in the Spike (S) protein compared to previous variants. Here we evaluate the potential effect of Omicron S mutations on S protein dynamics and ACE2 binding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff55599d5eca7b3120872f4e89747bb1
https://doi.org/10.1101/2021.12.14.472622
https://doi.org/10.1101/2021.12.14.472622
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 8, p e1009286 (2021)
The SARS-CoV-2 Spike protein needs to be in an open-state conformation to interact with ACE2 to initiate viral entry. We utilise coarse-grained normal mode analysis to model the dynamics of Spike and calculate transition probabilities between states
Externí odkaz:
https://doaj.org/article/8d83078b6d3d4c518b26ee6537a0c4cb