Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Natalia T, Freund"'
Autor:
Rita C. Acúrcio, Ron Kleiner, Daniella Vaskovich‐Koubi, Bárbara Carreira, Yulia Liubomirski, Carolina Palma, Adva Yeheskel, Eilam Yeini, Ana S. Viana, Vera Ferreira, Carlos Araújo, Michael Mor, Natalia T. Freund, Eran Bacharach, João Gonçalves, Mira Toister‐Achituv, Manon Fabregue, Solene Matthieu, Capucine Guerry, Ana Zarubica, Sarit Aviel‐Ronen, Helena F. Florindo, Ronit Satchi‐Fainaro
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract The first approved vaccines for human use against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are nanotechnology‐based. Although they are modular, rapidly produced, and can reduce disease severity, the currently availa
Externí odkaz:
https://doaj.org/article/b5734eacdf3b49c7be9c99d042cb5913
Autor:
Matteo Broketa, Aurélien Sokal, Michael Mor, Pablo Canales-Herrerias, Angga Perima, Annalisa Meola, Ignacio Fernández, Bruno Iannascoli, Guilhem Chenon, Alexis Vandenberghe, Laetitia Languille, Marc Michel, Bertrand Godeau, Sébastien Gallien, Giovanna Melica, Marija Backovic, Felix A. Rey, Jean Baudry, Natalia T. Freund, Matthieu Mahévas, Pierre Bruhns
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
SARS-CoV-2 mRNA vaccination generates protective B cell responses targeting the SARS-CoV-2 spike glycoprotein. Whereas anti-spike memory B cell responses are long lasting, the anti-spike humoral antibody response progressively wanes, making booster v
Externí odkaz:
https://doaj.org/article/7231211eeec64200bc51bc6db3b32475
Autor:
Ruofan Li, Michael Mor, Bingting Ma, Alex E. Clark, Joel Alter, Michal Werbner, Jamie Casey Lee, Sandra L. Leibel, Aaron F. Carlin, Moshe Dessau, Meital Gal-Tanamy, Ben A. Croker, Ye Xiang, Natalia T. Freund
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The neutralization of SARS-CoV-2 and variants of concern by nine monoclonal antibodies (mAb) isolated from convalescent donors infected with the Wuhan-Hu-1 strain alongside structural characterization of two of the mAbs in complex with the RBD and sp
Externí odkaz:
https://doaj.org/article/937c5f018769457995044ba9c3add8b9
Autor:
Ron Yefet, Nadav Friedel, Hadas Tamir, Ksenia Polonsky, Michael Mor, Lilach Cherry-Mimran, Eyal Taleb, David Hagin, Eli Sprecher, Tomer Israely, Natalia T. Freund
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105957- (2023)
Summary: Monkeypox virus (MPXV) resides in two forms; mature and enveloped, and depending on it, distinct proteins are displayed on the viral surface. Here, we expressed two MPXV antigens from the mature, and one from the enveloped form, and tested t
Externí odkaz:
https://doaj.org/article/19aea2903fef4c11adc9ce570a0ca458
Autor:
Natalia T. Freund
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 10, Pp 3551-3553 (2021)
Neutralizing antibodies are the basis of almost all approved prophylactic vaccines and the foundation of effective protection from pathogens, including the recently emerging SARS Coronavirus 2 (SARS-CoV-2). However, the contribution of antibodies to
Externí odkaz:
https://doaj.org/article/db08bf7f0e154401ac14d92b366b0fc5
Autor:
Avia Watson, Hao Li, Bingting Ma, Ronen Weiss, Daniele Bendayan, Lilach Abramovitz, Noam Ben-Shalom, Michael Mor, Erica Pinko, Michal Bar Oz, Zhenqi Wang, Fengjiao Du, Yu Lu, Jan Rybniker, Rony Dahan, Hairong Huang, Daniel Barkan, Ye Xiang, Babak Javid, Natalia T. Freund
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Antibody responses against Mycobacteria infection have been reported, but whether and how they impact anti-bacteria immunity in the host is unclear. Here the authors characterize human anti-Mycobacteria antibodies to find them targeting a Mycobacteri
Externí odkaz:
https://doaj.org/article/12d17b4408464c90aef7ffb8954e3827
Autor:
Keren Masha Rabinowitz, Michal Navon, Hadar Edelman-Klapper, Eran Zittan, Ariella Bar-Gil Shitrit, Idan Goren, Irit Avni-Biron, Jacob E. Ollech, Lev Lichtenstein, Hagar Banai-Eran, Henit Yanai, Yifat Snir, Maor H. Pauker, Adi Friedenberg, Adva Levy-Barda, Arie Segal, Yelena Broitman, Eran Maoz, Baruch Ovadia, Maya Aharoni Golan, Eyal Shachar, Shomron Ben-Horin, Nitsan Maharshak, Michal Mor, Haim Ben Zvi, Rami Eliakim, Revital Barkan, Tali Sharar-Fischler, Sophy Goren, Noy Krugliak, Edward Pichinuk, Michael Mor, Michal Werbner, Joel Alter, Hanan Abu-Taha, Kawsar Kaboub, Moshe Dessau, Meital Gal-Tanamy, Dani Cohen, Natalia T. Freund, Iris Dotan, on behalf of the Responses to COVID-19 Vaccine Israeli IBD Group
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1186 (2022)
Patients with inflammatory bowel disease (IBD) treated with anti-tumor-necrosis factor-alpha (TNFα) exhibited lower serologic responses one-month following the second dose of the COVID-19 BNT162b2 vaccine compared to those not treated with anti-TNF
Externí odkaz:
https://doaj.org/article/002599bbb4e74664a74f8cb9e8c3051d
Autor:
Michael Mor, Michal Werbner, Joel Alter, Modi Safra, Elad Chomsky, Jamie C Lee, Smadar Hada-Neeman, Ksenia Polonsky, Cameron J Nowell, Alex E Clark, Anna Roitburd-Berman, Noam Ben-Shalom, Michal Navon, Dor Rafael, Hila Sharim, Evgeny Kiner, Eric R Griffis, Jonathan M Gershoni, Oren Kobiler, Sandra Lawrynowicz Leibel, Oren Zimhony, Aaron F Carlin, Gur Yaari, Moshe Dessau, Meital Gal-Tanamy, David Hagin, Ben A Croker, Natalia T Freund
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009165 (2021)
The interactions between antibodies, SARS-CoV-2 and immune cells contribute to the pathogenesis of COVID-19 and protective immunity. To understand the differences between antibody responses in mild versus severe cases of COVID-19, we analyzed the B c
Externí odkaz:
https://doaj.org/article/0c87d14936274858891d55d77c97b63d
Autor:
Christopher O. Barnes, Harry B. Gristick, Natalia T. Freund, Amelia Escolano, Artem Y. Lyubimov, Harald Hartweger, Anthony P. West, Aina E. Cohen, Michel C. Nussenzweig, Pamela J. Bjorkman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Structure determination of glycosylated HIV-1 envelope (Env) trimers complexed with broadly neutralizing antibodies (bNAbs) promotes a better understanding of bNAb epitopes. Here the authors present the structures of natively-glycosylated Env in comp
Externí odkaz:
https://doaj.org/article/7030291af4434b7f82b5c09a827a0481
Autor:
Andrew T. McGuire, Matthew D. Gray, Pia Dosenovic, Alexander D. Gitlin, Natalia T. Freund, John Petersen, Colin Correnti, William Johnsen, Robert Kegel, Andrew B. Stuart, Jolene Glenn, Michael S. Seaman, William R. Schief, Roland K. Strong, Michel C. Nussenzweig, Leonidas Stamatatos
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
The induction of broadly neutralizing antibodies (bNAbs) is a goal of HIV-1 vaccine research. Here the authors demonstrate the ability of an HIV Env-derived immunogen to bind germline precursors of a class of bNAbs and to activate the corresponding B
Externí odkaz:
https://doaj.org/article/a9b9f94f37144c97936aee7cddb44bba