Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Natalia Salvadores"'
Autor:
Sebastián Oyarce-Pezoa, Guilherme Gischkow Rucatti, Francisco Muñoz-Carvajal, Nicole Sanhueza, Wileidy Gomez, Sandra Espinoza, Mario Leiva, Nicolás García, Daniela P. Ponce, Carol D. SanMartín, Diego Rojas-Rivera, Natalia Salvadores, Maria I. Behrens, Ute Woehlbier, Melissa Calegaro-Nassif, Mario Sanhueza
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized by protein accumulation in the brain as a main neuropathological hallmark. Among them, Aβ42 peptides tend to aggregate and create oligomers and plaques. M
Externí odkaz:
https://doaj.org/article/2ea3471a475747d3ac630b2c4a0a31ae
Autor:
Natalia Salvadores, Ines Moreno-Gonzalez, Nazaret Gamez, Gabriel Quiroz, Laura Vegas-Gomez, Marcela Escandón, Sebastian Jimenez, Javier Vitorica, Antonia Gutierrez, Claudio Soto, Felipe A. Court
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Alzheimer’s disease (AD) is a major adult-onset neurodegenerative condition with no available treatment. Compelling reports point amyloid-β (Aβ) as the main etiologic agent that triggers AD. Although there is extensive evidence of detrim
Externí odkaz:
https://doaj.org/article/fededd33034440f988ac2569fa67e475
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/2cf8f8aa1a554dc4b419bf25c4e73edd
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Alzheimer’s disease (AD) represents the most common age-related neurodegenerative disorder, affecting around 35 million people worldwide. Despite enormous efforts dedicated to AD research over decades, there is still no cure for the disease. Misfol
Externí odkaz:
https://doaj.org/article/61e8c67cda4b4c32a05f2587670f81da
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Aging constitutes the main risk factor for the development of neurodegenerative diseases. This represents a major health issue worldwide that is only expected to escalate due to the ever-increasing life expectancy of the population. Interestingly, ax
Externí odkaz:
https://doaj.org/article/d526211ee3f64b55a268e7e8875be0c3
Publikováno v:
Cell Reports, Vol 7, Iss 1, Pp 261-268 (2014)
Alzheimer's disease (AD) diagnosis is hampered by the lack of early, sensitive, and objective laboratory tests. We describe a sensitive method for biochemical diagnosis of AD based on specific detection of misfolded Aβ oligomers, which play a centra
Externí odkaz:
https://doaj.org/article/24353b6d253444b9bfec6e529e9665f4
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89970 (2014)
The structural integrity of cerebral vessels is compromised during ageing. Abnormal amyloid (Aβ) deposition in the vasculature can accelerate age-related pathologies. The cerebrovascular response associated with ageing and microvascular Aβ depositi
Externí odkaz:
https://doaj.org/article/75e6be1822804e9a9323059825a4fad2
Publikováno v:
Frontiers Research Topics ISBN: 9782832511268
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599a70d7da71fc9eea0f9e050e45bc4a
https://doi.org/10.3389/978-2-8325-1126-8
https://doi.org/10.3389/978-2-8325-1126-8
Autor:
Laura Vegas, Felipe A. Court, Ines Moreno-Gonzalez, Gabriel Quiroz, Claudio Soto, Javier Vitorica, Antonia Gutierrez, Marcela Escandón, Sebastian Jimenez, Nazaret Gamez Ruiz, Natalia Salvadores
Alzheimer’s disease (AD) is a major adult-onset neurodegenerative condition with no available treatment. Compelling reports point amyloid-β (Aβ) as the main etiologic agent that triggers AD. Although there is extensive evidence of detrimental cro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f275a9976d7cf6c383742fbcf861029
https://doi.org/10.1101/2021.08.27.457960
https://doi.org/10.1101/2021.08.27.457960
Autor:
Felipe A. Court, Natalia Salvadores
Publikováno v:
Expert opinion on therapeutic targets. 24(7)
Necroptosis is a programmed form of necrotic cell death. Growing evidence demonstrates that necroptosis contributes to cell demise in different pathological conditions including age-dependent neurodegenerative diseases (NDs). These findings open new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8078544a3916f28a621bff75eda91511
https://pubmed.ncbi.nlm.nih.gov/32310729
https://pubmed.ncbi.nlm.nih.gov/32310729