Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Natalia Realini"'
Autor:
Rosaria Greco, Chiara Demartini, Anna Maria Zanaboni, Miriam Francavilla, Angelo Reggiani, Natalia Realini, Rita Scarpelli, Daniele Piomelli, Cristina Tassorelli
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Targeting fatty acid amide hydrolase (FAAH) is a promising therapeutic strategy to combat certain forms of pain, including migraine headache. FAAH inhibitors, such as the O-biphenyl-3-yl carbamate URB597, have been shown to produce anti-hype
Externí odkaz:
https://doaj.org/article/9559696893eb4c0290426c1f26ad6375
Autor:
Michele Lai, Natalia Realini, Marco La Ferla, Ilaria Passalacqua, Giulia Matteoli, Anand Ganesan, Mauro Pistello, Chiara Maria Mazzanti, Daniele Piomelli
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Acid ceramidase (AC) is a lysosomal cysteine hydrolase that catalyzes the conversion of ceramide into fatty acid and sphingosine. This reaction lowers intracellular ceramide levels and concomitantly generates sphingosine used for sphingosine
Externí odkaz:
https://doaj.org/article/180c41426d6d457d925b68d89b55c644
Publikováno v:
Data in Brief, Vol 8, Iss , Pp 387-393 (2016)
The NMR spectra and data reported in this article refer to the research article titled “A simple and accurate protocol for absolute polar metabolite quantification in cell cultures using q-NMR” [1]. We provide the 1H q-NMR spectra of cell culture
Externí odkaz:
https://doaj.org/article/6755f3b4f3a64f0ca1a8ddf42b484d1f
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 4008 (2019)
Previous studies have shown that the sphingolipid-derived mediator sphingosine-1-phosphate (S1P) reduces food intake by activating G protein-coupled S1P receptor-1 (S1PR1) in the hypothalamus. Here, we examined whether feeding regulates hypothalamic
Externí odkaz:
https://doaj.org/article/7ceca160eb4344d3a66d10fed885b32a
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol 2007, Iss Issue 6, Pp 711-721 (2007)
Daniela Parolaro, Daniela Vigano’, Natalia Realini, Tiziana RubinoNeuroscience Center, DBSF, University of Insubria, Busto Arsizio, ItalyAbstract: This review will discuss the latest knowledge of how the endocannabinoid system might be involved in
Externí odkaz:
https://doaj.org/article/47d168f14dda4e23b9535c4723651f83
Autor:
Giuseppe Astarita, Agnesa Avanesian, Benedetto Grimaldi, Natalia Realini, Zuzana Justinova, Leight V Panlilio, Abdul Basit, Steven R Goldberg, Daniele Piomelli
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116961 (2015)
Methamphetamine is a highly addictive psychostimulant that causes profound damage to the brain and other body organs. Post mortem studies of human tissues have linked the use of this drug to diseases associated with aging, such as coronary atheroscle
Externí odkaz:
https://doaj.org/article/64071fd71a5f4300a0c68727055817c3
Autor:
Giuseppe Pepe, Luca Capocci, Federico Marracino, Natalia Realini, Paola Lenzi, Katiuscia Martinello, Tiziana Francesca Bovier, Terry Jo Bichell, Pamela Scarselli, Clotilde Di Cicco, Aaron B. Bowman, Filomena A. Digilio, Sergio Fucile, Francesco Fornai, Andrea Armirotti, Rosanna Parlato, Alba Di Pardo, Vittorio Maglione
Publikováno v:
Molecular Therapy. 31:282-299
Huntington's disease (HD) is a fatal neurodegenerative disorder with no effective cure currently available. Over the past few years our research has shown that alterations in sphingolipid metabolism represent a critical determinant in HD pathogenesis
Autor:
Giuseppe Pepe, Luca Capocci, Federico Marracino, Natalia Realini, Pamela Scarselli, Clotilde Di Cicco, Andrea Armirotti, Rosanna Parlato, Alba Di Pardo, Vittorio Maglione
Publikováno v:
I: Experimental therapeutics – preclinical.
Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonism
Autor:
Francesca Palese, Silvia Pontis, Natalia Realini, Alexa Torrens, Faizy Ahmed, Francesca Assogna, Clelia Pellicano, Paola Bossù, Gianfranco Spalletta, Kim Green, Daniele Piomelli
The lysosomal cysteine hydrolase N-acylethanolamine acid amidase (NAAA) deactivates palmitoylethanolamide (PEA), a lipid-derived PPAR-α agonist that is critically involved in the control of pain and inflammation. In this study, we asked whether NAAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4cf31b9d60651925f999bf11092cf1
https://escholarship.org/uc/item/9jx4m954
https://escholarship.org/uc/item/9jx4m954
Autor:
Francesca Palese, Silvia Pontis, Natalia Realini, Alexa Torrens, Faizy Ahmed, Francesca Assogna, Clelia Pellicano, Paola Bossù, Gianfranco Spalletta, Kim Green, Daniele Piomelli
The lysosomal cysteine hydrolase N-acylethanolamine acid amidase (NAAA) deactivates the lipidderived mediator palmitoylethanolamide (PEA), an endogenous PPAR-α agonist that is critically involved in the control of inflammation and nociception. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6369fcb2847cdd3df2789acb9e3f700d
https://doi.org/10.1101/2022.02.10.479850
https://doi.org/10.1101/2022.02.10.479850