Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Natalia Putkaradze"'
Autor:
Gonzalo Nahuel Bidart, David Teze, Charlotte Uldahl Jansen, Eleonora Pasutto, Natalia Putkaradze, Anna-Mamusu Sesay, Folmer Fredslund, Leila Lo Leggio, Olafur Ögmundarson, Sumesh Sukumara, Katrine Qvortrup, Ditte Hededam Welner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Blue denim, a billion-dollar industry, is currently dyed with indigo in an unsustainable process requiring harsh reducing and alkaline chemicals. Forming indigo directly in the yarn through indican (indoxyl-β-glucoside) is a promising alter
Externí odkaz:
https://doaj.org/article/d6c0a335cc824cc389dba6bbedc73dd5
Autor:
Rita Del Giudice, Natalia Putkaradze, Bruna Marques dos Santos, Cecilie Cetti Hansen, Christoph Crocoll, Mohammed Saddik Motawia, Folmer Fredslund, Tomas Laursen, Ditte Hededam Welner
Publikováno v:
Del Giudice, R, Putkaradze, N, dos Santos, B M, Hansen, C C, Crocoll, C, Motawia, M S, Fredslund, F, Laursen, T & Welner, D H 2022, ' Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis ', Plant Journal, vol. 111, no. 6, pp. 1539-1549 . https://doi.org/10.1111/tpj.15904
Cyanogenic glucosides are important defense molecules in plants with useful biological activities in animals. Their last biosynthetic step consists of a glycosylation reaction that confers stability and increases structural diversity and is catalyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897dc0dfe10ca6ba66cd58e48bedc4b9
https://doi.org/10.1111/tpj.15904
https://doi.org/10.1111/tpj.15904
Publikováno v:
Biotechnology Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::641f4b432c2872d397dc1060ad1c1917
https://doi.org/10.1002/biot.202200609
https://doi.org/10.1002/biot.202200609
Autor:
Gonzalo N. Bidart, Natalia Putkaradze, Folmer Fredslund, Christian Kjeldsen, Ander Garralda Ruiz, Jens Ø. Duus, David Teze, Ditte H. Welner
Publikováno v:
ACS Sustainable Chemistry & Engineering. 10:5078-5083
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69451d9566c4a1540865a31f79ccc702
https://doi.org/10.1021/acssuschemeng.1c07593
https://doi.org/10.1021/acssuschemeng.1c07593
Autor:
Gonzalo Bidart, David Teze, Charlotte Jansen, Eleonora Pasutto, Natalia Putkaradze, Anna-Mamusu Sesay, Folmer Fredslund, Leila Lo Leggio, Olafur Ögmundarson, Sumesh Sukumara, Katrine Qvortrup, Ditte Welner
Blue denim, a billion-dollar industry, is currently dyed with indigo in an unsustainable process requiring harsh reducing and alkaline chemicals. Several innovations aim to replace the damaging chemicals and processes with ecologically attractive alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a1216743434c5e2fcca50cf2eee0dc
https://doi.org/10.21203/rs.3.rs-2416810/v1
https://doi.org/10.21203/rs.3.rs-2416810/v1
Autor:
Katja Härtl, Thomas Hoffmann, Rita Bernhardt, Guangxin Sun, Wilfried Schwab, Tarik Fida, Natalia Putkaradze, Sina Bohnacker, Rafal Jonczyk
Publikováno v:
Plant Physiology. 184:1744-1761
C13-apocarotenoids (norisoprenoids) are carotenoid-derived oxidation products that perform important physiological functions in plants. Although their biosynthetic pathways have been extensively studied, their metabolism including glycosylation remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b473ca01b8ee99f7102eb35efaf461d7
https://doi.org/10.1104/pp.20.00953
https://doi.org/10.1104/pp.20.00953
Publikováno v:
ChemBioChem. 20:655-658
In this study, the ability of CYP109E1 from Bacillus megaterium DSM319 to metabolize cholesterol was investigated. This steroid was identified as a new substrate to be converted by CYP109E1 with adrenodoxin and adrenodoxin reductase as redox partners
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217795cb5d57052e0ee438161f897134
https://doi.org/10.1002/cbic.201800595
https://doi.org/10.1002/cbic.201800595
Publikováno v:
The FEBS Journal. 286:1240-1249
Bacterial P450s have considerable potential for biotechnological applications. The P450 CYP106A2 from Bacillus megaterium ATCC 13368 converts progesterone to several hydroxylated products that are important precursors for pharmaceutical substances. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12270a3cac3a8e154b549a4262c29bed
https://doi.org/10.1111/febs.14722
https://doi.org/10.1111/febs.14722
Autor:
Rita Bernhardt, Philip Hartz, Natalia Putkaradze, Michael C. Hutter, Mario Thevis, Josef Zapp
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 212
The human microsomal cytochrome P450 enzyme CYP46A1 plays a crucial role in cholesterol elimination from the brain. It performs a 24-hydroxylation of cholesterol and is of outstanding significance for memory and cognition. This study demonstrates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb9edd6142c34adcb895c50b7650dc8
https://pubmed.ncbi.nlm.nih.gov/34089835
https://pubmed.ncbi.nlm.nih.gov/34089835
Publikováno v:
Putkaradze, N, Tezé, D, Fredslund, F & Welner, D H 2021, ' Natural product C-glycosyltransferases-a scarcely characterised enzymatic activity with biotechnological potential ', Natural Product Reports, vol. 38, pp. 432-443 . https://doi.org/10.1039/d0np00040j
Covering: up to 2020C-Glycosyltransferases are enzymes that catalyse the transfer of sugar molecules to carbon atoms in substituted aromatic rings of a variety of natural products. The resulting β-C-glycosidic bond is more stable in vivo than most O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ead9b6096f2f2b4a7bbda8b4858a0f
https://orbit.dtu.dk/en/publications/f31552f4-f6b6-4cbd-818f-87ae0bc1cf76
https://orbit.dtu.dk/en/publications/f31552f4-f6b6-4cbd-818f-87ae0bc1cf76