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Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 197, no. 2, pp. 263-8
Journal of Experimental Medicine, vol. 197, no. 2, pp. 263-8
Toll-like receptors (TLRs) and members of the proinflammatory interleukin 1 receptor (IL-1R) family are dependent on the presence of MyD88 for efficient signal transduction. The bipartite nature of MyD88 (N-terminal death domain [DD] and COOH-termina