Safety and Potential Efficacy of Escalating Dose of Ustekinumab in Pediatric Crohn Disease (the Speed-up Study)

Autor: Anat Yerushalmy-Feler, Gemma Pujol-Muncunill, Javier Martin-de-Carpi, Kaija-Leena Kolho, Arie Levine, Christine Olbjørn, Maya Granot, Matteo Bramuzzo, Helena Rolandsdotter, Natalia Mouratidou, Ondrej Hradsky, Luca Scarallo, Manar Matar, Ramit Magen Rimon, Firas Rinawi, Tzippi Shalem, Hisham Najajra, Tim de Meij, Marina Aloi, Marta Velasco Rodríguez-Belvís, Patrizia Alvisi, Anna-Maria Schneider, Patrick van Rheenen, Víctor Manuel Navas-López, Fevronia Kiparissi, Josefa Barrio, Dan Turner, Shlomi Cohen

Publikováno v: Journal of Pediatric Gastroenterology and Nutrition, 75(6), 717-723. Lippincott Williams and Wilkins
Yerushalmy-Feler, A, Pujol-Muncunill, G, Martin-de-Carpi, J, Kolho, K-L, Levine, A, Olbjørn, C, Granot, M, Bramuzzo, M, Rolandsdotter, H, Mouratidou, N, Hradsky, O, Scarallo, L, Matar, M, Rimon, R M, Rinawi, F, Shalem, T, Najajra, H, de Meij, T, Aloi, M, Rodríguez-Belvís, M V, Alvisi, P, Schneider, A-M, van Rheenen, P, Navas-López, V C M, Kiparissi, F, Barrio, J, Turner, D & Cohen, S 2022, ' Safety and Potential Efficacy of Escalating Dose of Ustekinumab in Pediatric Crohn Disease (the Speed-up Study) : A Multicenter Study from the Pediatric IBD Porto Group of ESPGHAN ', Journal of Pediatric Gastroenterology and Nutrition, vol. 75, no. 6, pp. 717-723 . https://doi.org/10.1097/MPG.0000000000003608

OBJECTIVES: Escalation of the ustekinumab (UST) maintenance dosage was effective in adults with Crohn disease (CD), but no data are available for children. We evaluated the effectiveness and safety of dose escalation of UST in pediatric CD. METHODS:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9790dae26a87ed87de98ba1e23fe231b
https://research.rug.nl/en/publications/a0741af3-0a6b-4f24-bc40-ec3617ad0395

Patients with both Langerhans cell histiocytosis and Crohn’s disease highlight a common role of interleukin‐23

Autor: Martin Jädersten, Egle Kvedaraite, Jan-Inge Henter, Natalia Mouratidou, Jenée Mitchell, George Kannourakis, Fleur Cohen-Aubart, Yenan T. Bryceson, Magda Lourda, Selma Olsson Åkefeldt, Maja Ideström, George Z. Rassidakis, Tatiana von Bahr Greenwood, Julien Haroche, HongYa Han, Bianca Tesi, Mattias Svensson

Publikováno v: Acta Paediatrica (Oslo, Norway : 1992)
Acta Paediatrica
Acta Paediatrica, Wiley, In press, ⟨10.1111/apa.15590⟩

International audience; Aim: To present the first case series of patients with Langerhans cell histiocytosis (LCH) also affected by Crohn's disease (CD), both of which are granulomatous diseases, and in LCH investigate the role of interleukin (IL)-23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c9d399cd737e8e7b6016cee4247f68
https://doi.org/10.1111/apa.15590

Identification of Childhood-Onset Inflammatory Bowel Disease in Swedish Healthcare Registers: A Validation Study

Autor: Natalia, Mouratidou, Petter, Malmborg, Jacob, Järås, Vignir, Sigurdsson, Olof, Sandström, Ulrika L, Fagerberg, Gabriella, Bröms, Jonas F, Ludvigsson, Ola, Olén

Publikováno v: Clinical epidemiology. 14

The Swedish National Patient Register (NPR) is often used in observational studies of childhood-onset inflammatory bowel disease (IBD) (18 years of age) and its subtypes, but the validity of previously used register-based algorithms for capturing chi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::996cbbdf65f491147d048c7c93795b09
https://pubmed.ncbi.nlm.nih.gov/35520278