Zobrazeno 1 - 4
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pro vyhledávání: '"Natalia Melnichuk"'
Publikováno v:
The 1st International Electronic Conference on Pharmaceutics.
(1) Background: It is known that RNA in Na+ salt form has only immunomodulatory activity, and in acid form additionally acquires anti-inflammatory activity and in combination with D-mannitol acquires an even broader antiviral effect. The study aimed
Autor:
Natalia Melnichuk, Zenoviy Tkachuk
Publikováno v:
Proceedings of 3rd International Electronic Conference on Medicinal Chemistry.
The influenza (flu) virus infection induces an upexpression of tlr3, tlr7, tlr8, nfκb1, nfκbiα, nos2, xdh and other genes in mice lung. The nos2 and xdh upexpression causes overproduction of free radicals that lead to lung tissue damage. The upexp
Publikováno v:
Proceedings of 2nd International Electronic Conference on Medicinal Chemistry.
The influenza virus surface glycoprotein hemagglutinin (HA) is responsible for viral attachment to sialic acid-containing host cell receptors and it facilitates the initial stage of viral infection. Natural and synthetic oligoribonucleotides (ORNs) h
Autor:
Zenoviy Tkachuk, Kristina Naumenko, Svitlana Zagorodnya, Baranova Gv, Anna Golovan, Natalia Melnichuk
Publikováno v:
Proceedings of 2nd International Electronic Conference on Medicinal Chemistry.
Inhibition of virus-cell interactions, which are required for virus replication, constitutes an exciting area of research for the discovery of novel antiviral agents. RNA based drugs are in clinical use for treatment of infectious diseases as immunom