Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Natalia Maltseva"'
Autor:
Youngchang Kim, Seung Hwan Lee, Priyanka Gade, Maren Nattermann, Natalia Maltseva, Michael Endres, Jing Chen, Philipp Wichmann, Yang Hu, Daniel G. Marchal, Yasuo Yoshikuni, Tobias J. Erb, Ramon Gonzalez, Karolina Michalska, Andrzej Joachimiak
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract 2-Hydroxyacyl-CoA lyase/synthase (HACL/S) is a thiamine diphosphate (ThDP)-dependent versatile enzyme originally discovered in the mammalian α-oxidation pathway. HACL/S natively cleaves 2-hydroxyacyl-CoAs and, in its reverse direction, cond
Externí odkaz:
https://doaj.org/article/6aa21acb3e0a48658c899fdf3ca1d48f
Autor:
Youngchang Kim, Natalia Maltseva, Christine Tesar, Robert Jedrzejczak, Michael Endres, Heng Ma, Haley L. Dugan, Christopher T. Stamper, Changsoo Chang, Lei Li, Siriruk Changrob, Nai-Ying Zheng, Min Huang, Arvind Ramanathan, Patrick Wilson, Karolina Michalska, Andrzej Joachimiak
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108976- (2024)
Summary: Coronavirus nucleocapsid protein (NP) of SARS-CoV-2 plays a central role in many functions important for virus proliferation including packaging and protecting genomic RNA. The protein shares sequence, structure, and architecture with nucleo
Externí odkaz:
https://doaj.org/article/e75293ccbb074ec98180a116ff5e64b9
Autor:
Youngchang Kim, Jacek Wower, Natalia Maltseva, Changsoo Chang, Robert Jedrzejczak, Mateusz Wilamowski, Soowon Kang, Vlad Nicolaescu, Glenn Randall, Karolina Michalska, Andrzej Joachimiak
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Youngchang Kim, Jacek Wower, and colleagues explore the sequence specificity, metal ion dependence and catalytic mechanism of the Nsp15 endoribonuclease NendoU from SARS-CoV-2. The authors also solve five new crystal structures of the enzyme in compl
Externí odkaz:
https://doaj.org/article/c2e1555f80bc4eb28bc2085247f56486
Autor:
Magdalena Makowska-Grzyska, Youngchang Kim, Suresh Kumar Gorla, Yang Wei, Kavitha Mandapati, Minjia Zhang, Natalia Maltseva, Gyan Modi, Helena I Boshoff, Minyi Gu, Courtney Aldrich, Gregory D Cuny, Lizbeth Hedstrom, Andrzej Joachimiak
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0138976 (2015)
Tuberculosis (TB) remains a worldwide problem and the need for new drugs is increasingly more urgent with the emergence of multidrug- and extensively-drug resistant TB. Inosine 5'-monophosphate dehydrogenase 2 (IMPDH2) from Mycobacterium tuberculosis
Externí odkaz:
https://doaj.org/article/49962dbbbacf43ff908481f32290ecf0
Autor:
Natalia Maltseva
Publikováno v:
Ukrainian musicology. 47:114-120
Peculiarities of work on piano technique in the class of the Kyiv teacher of NMAU named after P.I. Tchaikovsky Aza Roshchina - a bright representative of the Kiev piano school is considered. The main directions of work on the technical apparatus are
Autor:
Deviprasad R. Gollapalli, Gregory D. Cuny, Adhar C. Manna, Natalia Maltseva, Barry B. Snider, Yubo Zhang, Mohana Rao Vippila, Ann P. Lawson, Lizbeth Hedstrom, Minjia Zhang, Youngchang Kim, David M Rothstein, Shibin Chacko, Petr Kuzmic, Xingyou Wang, Andrzej Joachimiak, Ryan T Cullinane, Gyan Modi, Gary M Marqus, Ambrose L. Cheung, Judy L.M. Kotler
Publikováno v:
ACS Infectious Diseases. 7:3062-3076
Many bacterial pathogens, including Staphylococcus aureus, require inosine 5'-monophosphate dehydrogenase (IMPDH) for infection, making this enzyme a promising new target for antibiotics. Although potent selective inhibitors of bacterial IMPDHs have
Autor:
Brooke Schuster, Mason R Firpo, Dominique Missiakas, Susan Baker, Hyun Lee, Jennifer K. DeMarco, Marco Vignuzzi, Krysten A. Jones, Bjoern Meyer, Vishnu Nair, Robert Jedrzejczak, Savaş Tay, Bryan C. Dickinson, Jason Botten, Emily A. Bruce, Vincent Mastrodomenico, Amornrat O'Brien, Kenneth E. Palmer, Madaline M. Schmidt, Bryan C. Mounce, Nir Drayman, Christopher B. Brooke, Nicholas S. Heaton, Natalia Maltseva, Saara-Anne Azizi, Glenn Randall, Heather M. Froggatt, Andrzej Joachimiak, Siquan Chen, Rahul S. Kathayat, Steve Dvorkin, Anastasia Tomatsidou, Miguel Ángel Muñoz-Alía, William E. Severson, Kevin Furlong, Vlad Nicolaescu, Kemin Tan, Kyu-yeon Han
Publikováno v:
bioRxiv
There is an urgent need for anti-viral agents that treat SARS-CoV-2 infection. The shortest path to clinical use is repurposing of drugs that have an established safety profile in humans. Here, we first screened a library of 1,900 clinically safe dru
Autor:
L Rodrigo Rosas-Becerra, Nelly Selem-Mojica, Robert Jedrzejczak, Natalia Maltseva, Karolina Michalska, Andrzej Joachimiak, Deborah T. Hung, Francisco Barona-Gómez, Samantha Wellington
Publikováno v:
Protein Science : A Publication of the Protein Society
Intracellular growth and pathogenesis of Chlamydia species is controlled by the availability of tryptophan, yet the complete biosynthetic pathway for l‐Trp is absent among members of the genus. Some representatives, however, preserve genes encoding
Autor:
Alfa Herrera, Youngchang Kim, Jiexi Chen, Robert Jedrzejczak, Shantanu Shukla, Natalia Maltseva, Grazyna Joachimiak, Lukas Welk, Grant Wiersum, Lukasz Jaroszewski, Adam Godzik, Andrzej Joachimiak, Karla J. F. Satchell
Publikováno v:
J Bacteriol
Alpha-pore-forming toxins (α-PFTs) are secreted by many species of bacteria, including Escherichia coli, Aeromonas hydrophila, and Bacillus thuringiensis, as part of their arsenal of virulence factors, and are often cytotoxic. In particular, for α-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c475b7a7442fadd823711cfb26167645
https://europepmc.org/articles/PMC9112891/
https://europepmc.org/articles/PMC9112891/
Autor:
Popov, Anatoly, Gritsenko, Ekaterina, Trishkina, Elizaveta, Natalia, Maltseva, Demidyuk, Valentina
Publikováno v:
AIP Conference Proceedings; 11/1/2022, Vol. 2647 Issue 1, p1-7, 7p