Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Natalia Malikowska-Racia"'
Autor:
Piotr Popik, Ewelina Cyrano, Diana Piotrowska, Malgorzata Holuj, Joanna Golebiowska, Natalia Malikowska-Racia, Agnieszka Potasiewicz, Agnieszka Nikiforuk
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Traditional methods of rat social behavior assessment are extremely time-consuming and susceptible to the subjective biases. In contrast, novel digital techniques allow for rapid and objective measurements. This study sought to assess the feasibility
Externí odkaz:
https://doaj.org/article/be7c51615a5846f184bc09f5d99008ac
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Posttraumatic stress disorder (PTSD) has been associated with abnormal regulation of the hypothalamic-pituitary-adrenal gland axis (HPA). Women demonstrate a more robust HPA response and are twice as likely to develop PTSD than men. The role of sex h
Externí odkaz:
https://doaj.org/article/1fcd0e0f6d2344759f53d7d112e853c0
Autor:
Kinga Sałaciak, Natalia Malikowska-Racia, Klaudia Lustyk, Agata Siwek, Monika Głuch-Lutwin, Grzegorz Kazek, Justyna Popiół, Jacek Sapa, Henryk Marona, Dorota Żelaszczyk, Karolina Pytka
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 744 (2021)
The increasing number of patients reporting depressive symptoms requires the design of new antidepressants with higher efficacy and limited side effects. As our previous research showed, 2-methoxyphenylpiperazine derivatives are promising candidates
Externí odkaz:
https://doaj.org/article/ffe77bfce64941849e5dbfd0d2020f70
Autor:
Piotr Popik, Adam Hogendorf, Ryszard Bugno, Shaun Yon-Seng Khoo, Pawel Zajdel, Natalia Malikowska-Racia, Agnieszka Nikiforuk, Joanna Golebiowska
Publikováno v:
Psychopharmacology. 239:1689-1703
Rationale Ketamine and psilocybin belong to the rapid-acting antidepressants but they also produce psychotomimetic effects including timing distortion. It is currently debatable whether these are essential for their therapeutic actions. As depressed
Autor:
Maciej Pawłowski, Xavier Bantreil, Natalia Malikowska-Racia, Ryszard Bugno, Joanna Golebiowska, Jean Martinez, Frédéric Lamaty, Séverine Chaumont-Dubel, Gilles Subra, Paweł Zajdel, Grzegorz Satała, Piotr Popik, Katarzyna Grychowska, Andrzej J. Bojarski, Philippe Marin, Szczepan Mogilski, Rafał Kurczab, Agnieszka Nikiforuk, Tomasz Kos
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2021, 64 (18), pp.13279-13298. ⟨10.1021/acs.jmedchem.1c00224⟩
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (18), pp.13279-13298. ⟨10.1021/acs.jmedchem.1c00224⟩
Journal of Medicinal Chemistry, 2021, 64 (18), pp.13279-13298. ⟨10.1021/acs.jmedchem.1c00224⟩
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (18), pp.13279-13298. ⟨10.1021/acs.jmedchem.1c00224⟩
International audience; In line with recent clinical trials demonstrating that ondansetron, a 5-HT3 receptor (5-HT3R) antagonist, ameliorates cognitive deficits of schizophrenia and the known procognitive effects of 5-HT6 receptor (5-HT6R) antagonist
Autor:
Natalia Malikowska-Racia, Joanna Golebiowska, Agnieszka Nikiforuk, Shaun Yon-Seng Khoo, Piotr Popik
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 67
(S)-ketamine-induced rapid-acting antidepressant effects have revolutionized the pharmacotherapy of major depression; however, this medication also produces psychotomimetic effects such as timing distortion. While (R)-ketamine produces fewer dissocia
Autor:
Katarzyna Grychowska, Agnieszka Olejarz-Maciej, Klaudia Blicharz, Wojciech Pietruś, Tadeusz Karcz, Rafał Kurczab, Paulina Koczurkiewicz, Agata Doroz-Płonka, Gniewomir Latacz, Abdul Raheem Keeri, Kamil Piska, Grzegorz Satała, Joanna Pęgiel, Wojciech Trybała, Magdalena Jastrzębska-Więsek, Andrzej J. Bojarski, Frédéric Lamaty, Anna Partyka, Maria Walczak, Martyna Krawczyk, Natalia Malikowska-Racia, Piotr Popik, Paweł Zajdel
The incorporation of the fluorine motif is a strategy widely applied in drug design for modulating the activity, physicochemical parameters, and metabolic stability of chemical compounds. In this study, we attempted to reduce the affinity for ether-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f37b26f52cb6eaf288753ac901311bc
https://ruj.uj.edu.pl/xmlui/handle/item/293057
https://ruj.uj.edu.pl/xmlui/handle/item/293057
Autor:
Grzegorz Kazek, Henryk Marona, Karolina Pytka, Dorota Żelaszczyk, Jacek Sapa, Natalia Malikowska-Racia, Justyna Popiół, Agata Siwek, Kinga Sałaciak, Klaudia Lustyk, Monika Głuch-Lutwin
Publikováno v:
Pharmaceuticals, Vol 14, Iss 744, p 744 (2021)
Pharmaceuticals
Volume 14
Issue 8
Pharmaceuticals
Volume 14
Issue 8
The increasing number of patients reporting depressive symptoms requires the design of new antidepressants with higher efficacy and limited side effects. As our previous research showed, 2-methoxyphenylpiperazine derivatives are promising candidates
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Posttraumatic stress disorder (PTSD) has been associated with abnormal regulation of the hypothalamic-pituitary-adrenal gland axis (HPA). Women demonstrate a more robust HPA response and are twice as likely to develop PTSD than men. The role of sex h
Publikováno v:
Neurotoxicity Research
Nowadays cognitive impairments are a growing unresolved medical issue which may accompany many diseases and therapies, furthermore, numerous researchers investigate various neurobiological aspects of human memory to find possible ways to improve it.