Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Natalia Maciejewska"'
Autor:
Agnieszka Chylewska, Aleksandra M. Dąbrowska, Sandra Ramotowska, Natalia Maciejewska, Mateusz Olszewski, Maciej Bagiński, Mariusz Makowski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/76ac7ca46fb544dd832d66a166e6053f
Autor:
Mateusz Olszewski, Natalia Maciejewska, Anoop Kallingal, Agnieszka Chylewska, Aleksandra M. Dąbrowska, Małgorzata Biedulska, Mariusz Makowski, José M. Padrón, Maciej Baginski
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractHuman DNA topoisomerases are essential for crucial cellular processes, including DNA replication, transcription, chromatin condensation, and maintenance of its structure. One of the significant strategies employed in cancer treatment involves
Externí odkaz:
https://doaj.org/article/3e3a34c4c647494a825b38608feb0e37
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractAnthraquinones have attracted considerable interest in the realm of cancer treatment owing to their potent anticancer properties. This study evaluates the potential of a series of new anthraquinone derivatives as anticancer agents for non-sma
Externí odkaz:
https://doaj.org/article/69a7a227d5d0437baf6ce40fa63d7d05
Autor:
Jan Jakub Lica, Katarzyna Gucwa, Mateusz Heldt, Anna Stupak, Natalia Maciejewska, Natalia Ptaszyńska, Anna Łęgowska, Bhaskar Pradhan, Agata Gitlin-Domagalska, Dawid Dębowski, Joanna Jakóbkiewicz-Banecka, Krzysztof Rolka
Publikováno v:
Molecules, Vol 29, Iss 3, p 678 (2024)
The fusion of penetrating peptides (PPs), e.g., cell penetration peptides (CPPs) or antimicrobial peptides (AMPs), together with antimicrobial agents is an expanding research field. Specific AMPs, such as lactoferricin B (LfcinB), have demonstrated s
Externí odkaz:
https://doaj.org/article/b458baa1fa6644fcaa0748090d7daa1a
Autor:
Natalia Maciejewska, Mateusz Olszewski, Jakub Jurasz, Maciej Baginski, Maryna Stasevych, Viktor Zvarych, Marco Folini, Nadia Zaffaroni
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-10 (2022)
Abstract Telomerase reactivation is one of the hallmarks of cancer, which plays an important role in cellular immortalization and the development and progression of the tumor. Chemical telomerase inhibitors have been shown to trigger replicative sene
Externí odkaz:
https://doaj.org/article/7609c4d1d9d748899394df7ad49ec4c3
Autor:
Małgorzata Ryczkowska, Natalia Maciejewska, Mateusz Olszewski, Milena Witkowska, Sławomir Makowiec
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The anticancer properties of quinolones is a topic of interest among researchers in the scientific world. Because these compounds do not cause side effects, unlike the commonly used cytostatics, they are considered a promising source of new
Externí odkaz:
https://doaj.org/article/e14121f0571f4930bf5c2ae8b0ece9d0
Autor:
Małgorzata Ryczkowska, Natalia Maciejewska, Mateusz Olszewski, Milena Witkowska, Sławomir Makowiec
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Colorectal cancer (CRC) is the most commonly diagnosed cancer in Europe and the United States and the second leading cause of cancer related mortality. A therapeutic strategy used for the treatment of CRC involves targeting the intracellular
Externí odkaz:
https://doaj.org/article/fb224a41963143b185f729852d6f25eb
Autor:
Natalia Maciejewska, Mateusz Olszewski, Jakub Jurasz, Marcin Serocki, Maria Dzierzynska, Katarzyna Cekala, Ewa Wieczerzak, Maciej Baginski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Lung cancer is considered to account for approximately one-fifth of all malignant tumor-related deaths worldwide and is therefore one of the most lethal malignancies. Pyrazole scaffold possesses a wide range of biological and pharmacological
Externí odkaz:
https://doaj.org/article/35871e08810047eba122a7a0eabb4f8b
Autor:
Paulina Mech-Warda, Artur Giełdoń, Anna Kawiak, Natalia Maciejewska, Mateusz Olszewski, Mariusz Makowski, Agnieszka Chylewska
Publikováno v:
Molecules, Vol 27, Iss 12, p 3704 (2022)
Pyrazine and its derivatives are a large group of compounds that exhibit broad biological activity, the changes of which can be easily detected by a substituent effect or a change in the functional group. The present studies combined theoretical rese
Externí odkaz:
https://doaj.org/article/b025e96e856f492199b2e733258b6e6d
Autor:
Jan Jakub Lica, Miłosz Wieczór, Grzegorz Jan Grabe, Mateusz Heldt, Marta Jancz, Majus Misiak, Katarzyna Gucwa, Wioletta Brankiewicz, Natalia Maciejewska, Anna Stupak, Maciej Bagiński, Krzysztof Rolka, Andrzej Hellmann, Andrzej Składanowski
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4931 (2021)
Poor efficiency of chemotherapeutics in the eradication of Cancer Stem Cells (CSCs) has been driving the search for more active and specific compounds. In this work, we show how cell density-dependent stage culture profiles can be used in drug develo
Externí odkaz:
https://doaj.org/article/6d06abadc9dd4b6e96a596944728f694