Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Natalia Liem"'
Autor:
Liang Kee Goh, Natalia Liem, Aadhitthya Vijayaraghavan, Gengbo Chen, Pei Li Lim, Kae-Jack Tay, Michelle Chang, John Soon Wah Low, Adita Joshi, Hong Hong Huang, Emarene Kalaw, Puay Hoon Tan, Wen-Son Hsieh, Wei Peng Yong, Joshi Alumkal, Hong Gee Sim
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91666 (2014)
We aimed to identify a prostate cancer DNA hypermethylation microarray signature (denoted as PHYMA) that differentiates prostate cancer from benign prostate hyperplasia (BPH), high from low-grade and lethal from non-lethal cancers. This is a non-rand
Externí odkaz:
https://doaj.org/article/d7fee0e656a4443f97c9947f46d69f2b
Autor:
Foong Ying Wong, Natalia Liem, Chen Xie, Fui Leng Yan, Wing Cheong Wong, Lingzhi Wang, Wei-Peng Yong
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50786 (2012)
Although gemcitabine is highly active in several cancer types, intrinsic and acquired drug resistance remains a major challenge. Overexpression of Bcl-2 has been associated with gemcitabine resistance. The aim of this study is to determine whether go
Externí odkaz:
https://doaj.org/article/f5c5027d887e4efabdbe7242f902ef83
Autor:
Wei Peng Yong, Vaidehi Krishnan, Natalia Liem, Praveen C. Peethala, Fui Leng Yan, Mei Shi Yeo, Shi Hui Tan, Vinod Vijay Subhash
Table S1. Primers used to amplify ATM gene; Figure S1. siRNA knock down of ATM in HGC 27 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa776843d46e11e58dc84836c9d7968
https://doi.org/10.1158/1535-7163.22508752
https://doi.org/10.1158/1535-7163.22508752
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:Drinking mineral water has shown some benefit in reducing urinary stone recurrences in some studies. Our pilot study in 10 healthy subjects revealed significant reduction...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5066df3458e8577d2c59f868978bc04f
https://doi.org/10.1097/ju.0000000000000898.09
https://doi.org/10.1097/ju.0000000000000898.09
Autor:
Jason Yongsheng Chan, Khay Guan Yeoh, Natalia Liem, Yong Wei Peng, Manish Mani Subramaniam, Xn Yii Lim, Barry Iacopetta, Pei Li Lim, Manuel Salto-Tellez, Marie Loh, Richie Soong
Publikováno v:
Molecular Carcinogenesis. 53:98-108
The degree of gene hypermethylation in non-neoplastic colonic mucosa (NNCM) is a potentially important event in the development of colorectal cancer (CRC), particularly for the subgroup with a CpG island methylator phenotype (CIMP). In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91baa51d9a808a414db9d021be137265
https://doi.org/10.1002/mc.21951
https://doi.org/10.1002/mc.21951
Autor:
Veena Gopalakrishnan, Chia Huey Ooi, Natalia Liem, Julian Lee, Minghui Lee, Yonghui Wu, Dan Huang, Hermioni Zouridis, Iain Beehuat Tan, Lai Ling Cheng, Khay Guan Yeoh, Wei Peng Yong, Jeanie Wu, Patrick Tan, Tatiana Ivanova, Sun Young Rha, Luo Qin, Bin Tean Teh
Publikováno v:
Gut. 62:22-33
Objective Cisplatin is a widely used gastric cancer (GC) chemotherapy; however, genetic factors regulating GC responses to cisplatin remain obscure. Identifying genes regulating cisplatin resistance could aid clinicians in tailoring treatments, by di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19751692073338ca1aca1d4ff376e012
https://doi.org/10.1136/gutjnl-2011-301113
https://doi.org/10.1136/gutjnl-2011-301113
Autor:
Wei Peng Yong, Shi Hui Tan, Fui Leng Yan, Mei Shi Yeo, Praveen C. Peethala, Natalia Liem, Vaidehi Krishnan, Vinod Vijay Subhash
Publikováno v:
Molecular cancer therapeutics. 15(12)
Identification of synthetically lethal cellular targets and synergistic drug combinations is important in cancer chemotherapy as they help to overcome treatment resistance and increase efficacy. The Ataxia Telangiectasia Mutated (ATM) kinase is a nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98afed32e6bb1171467d0dba41c6bf52
https://pubmed.ncbi.nlm.nih.gov/27638859
https://pubmed.ncbi.nlm.nih.gov/27638859
Autor:
Wei Peng Yong, Chee Leong Cheng, Pei Li Lim, Aparna Vaithilingam, Natalia Liem, Manuel Salto-Tellez, Richie Soong, Marie Loh
Publikováno v:
Diagnostic Molecular Pathology. 19:243-247
The recent emergence of high-throughput arrays for methylation analysis has made the influence of tumor content on the interpretation of methylation levels increasingly pertinent. However, to what degree does tumor content have an influence, and what
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8152ce86ae40e610a17e5744dd4f4f
https://doi.org/10.1097/pdm.0b013e3181de4396
https://doi.org/10.1097/pdm.0b013e3181de4396
Autor:
Glenn M. Marshall, Richard B. Lock, Alison M. Rice, Michelle Haber, Chengyuan Xue, Natalia Liem, Christopher G. Milross, Monica L. Farnsworth, Mayamin Tajbakhsh, Murray D. Norris
Publikováno v:
Blood. 99:4100-4108
Acute lymphoblastic leukemia cells from 19 children, including 7 who remain in first complete remission (CR1), were engrafted into nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice. High-level infiltration of bone marrow, spleen, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d372e6a9c39c39e281bb15809373525
https://doi.org/10.1182/blood.v99.11.4100
https://doi.org/10.1182/blood.v99.11.4100
Autor:
Marie Loh, Benedict Yan, Zuan Yu Mok, Manuel Salto-Tellez, Wei Peng Yong, Brendan Pang, Aparna Vaithilingam, Eiram Elahi, Chee Leong Cheng, Barry Iacopetta, Richie Soong, Natalia Liem, Nur Sabrina Sapari, Pei Li Lim
Publikováno v:
BMC Gastroenterology
Background Methylation-induced silencing of promoter CpG islands in tumor suppressor genes plays an important role in human carcinogenesis. In colorectal cancer, the CpG island methylator phenotype (CIMP) is defined as widespread and elevated levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27552f80928f60ce6e237df4ad73cb3e
https://doi.org/10.1186/1471-230x-14-55
https://doi.org/10.1186/1471-230x-14-55