Výsledky vyhledávání - "Natalia Lautherbach"

Akademický článek

β2-Adrenoceptors activation regulates muscle trophic-related genes following acute resistance exercise in mice

Autor: Ronaldo L. Abdalla-Silva, Gustavo O. Zanetti, Natalia Lautherbach, Aline Zanatta Schavinski, Lilian C. Heck, Dawit A. P. Gonçalves, Isis C. Kettelhut, Luiz C. C. Navegantes, Wilian A. Silveira

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

Resistance exercise (RE) training and pharmacological stimulation of β2-Adrenoceptors (β2-ARs) alone can promote muscle hypertrophy and prevent muscle atrophy. Although the activation of the sympathetic nervous system (SNS) is a well-established re

Externí odkaz: https://doaj.org/article/044b5bfe897a441f8b8fad9b91c15773

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Akademický článek

Urocortin 2 promotes hypertrophy and enhances skeletal muscle function through cAMP and insulin/IGF-1 signaling pathways

Autor: Natalia Lautherbach, Dawit A.P. Gonçalves, Wilian A. Silveira, Sílvia Paula-Gomes, Rafael Rossi Valentim, Neusa M. Zanon, Marcelo G. Pereira, Elen H. Miyabara, Luiz C.C. Navegantes, Isis C. Kettelhut

Publikováno v: Molecular Metabolism, Vol 60, Iss , Pp 101492- (2022)

Objective: Although it is well established that urocortin 2 (Ucn2), a peptide member of the corticotrophin releasing factor (CRF) family, and its specific corticotrophin-releasing factor 2 receptor (CRF2R) are highly expressed in skeletal muscle, the

Externí odkaz: https://doaj.org/article/8fb5755fb87d45968e670b90f0f6b511

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Akademický článek

Interleukin-1 receptor-induced PGE2 production controls acetylcholine-mediated cardiac dysfunction and mortality during scorpion envenomation

Autor: Mouzarllem B. Reis, Fernanda L. Rodrigues, Natalia Lautherbach, Alexandre Kanashiro, Carlos A. Sorgi, Alyne F. G. Meirelles, Carlos A. A. Silva, Karina F. Zoccal, Camila O. S. Souza, Simone G. Ramos, Alessandra K. Matsuno, Lenaldo B. Rocha, Helio C. Salgado, Luiz C. C. Navegantes, Ísis C. Kettelhut, Palmira Cupo, Luiz G. Gardinassi, Lúcia H. Faccioli

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

Cardiac dysfunction is a major complication that precedes death after scorpion envenomation. Here, authors show that heart failure and mortality are caused by excessive acetylcholine release, which requires IL-1R-dependent PGE2 production. Dexamethas

Externí odkaz: https://doaj.org/article/3824a55bb5ce42fc8ddfb1f913df0a2a

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Akademický článek

Insulin/IGF1 signalling mediates the effects of β2‐adrenergic agonist on muscle proteostasis and growth

Autor: Dawit A. Gonçalves, Wilian A. Silveira, Leandro H. Manfredi, Flávia A. Graça, Andrea Armani, Enrico Bertaggia, Brian T. O´Neill, Natalia Lautherbach, Juliano Machado, Leonardo Nogara, Marcelo G. Pereira, Diletta Arcidiacono, Stefano Realdon, C. Ronald Kahn, Marco Sandri, Isis C. Kettelhut, Luiz Carlos C. Navegantes

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 2, Pp 455-475 (2019)

Abstract Background Stimulation of β2‐adrenoceptors can promote muscle hypertrophy and fibre type shift, and it can counteract atrophy and weakness. The underlying mechanisms remain elusive. Methods Fed wild type (WT), 2‐day fasted WT, muscle‐

Externí odkaz: https://doaj.org/article/f341a8776db04f97b5771d9cee49e3e4

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Dissertation/ Thesis

Os efeitos da urocortina 2 no metabolismo de proteínas em músculos esqueléticos de roedores

Autor: Natalia Lautherbach Ennes da Silva

Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

A urocortina 2 (Ucn2) é um peptídeo que pertence à família dos fatores liberadores de corticotrofina (CRF) e, assim como seu receptor específico CRF2R? (corticotropin releasing factor receptor type 2?), encontram-se expressos no músculo esquel�

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/17/17134/tde-22112018-084729/

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Th17 cell-linked mechanisms mediate vascular dysfunction induced by testosterone in a mouse model of gender-affirming hormone therapy

Autor: Jeimison D. Santos, José T. Oliveira-Neto, Paula R. Barros, Luis E. A. Damasceno, Natalia Lautherbach, Ana P. Assis, Carlos A. A. Silva, Carlos A. Sorgi, Lucia H. Faccioli, Isis C. Kettelhut, Hélio C. Salgado, Fernando S. Carneiro, José C. Alves-Filho, Rita C. Tostes

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 323:H322-H335

Clinical data point to adverse cardiovascular events elicited by testosterone replacement therapy. Testosterone is the main hormone used in gender-affirming hormone therapy (GAHT) by transmasculine people. However, the cardiovascular impact of testos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd33ee9d555e313ed0e090b87ad53946
https://doi.org/10.1152/ajpheart.00182.2022

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Glucocorticoids decrease thermogenic capacity and increase triacylglycerol synthesis by glycerokinase activation in the brown adipose tissue of rats

Autor: Ana Paula Assis, Karine Emanuelle Silva, Natalia Lautherbach, Henrique Jorge Novaes Morgan, Maria Antonieta Rissato Garófalo, Neusa Maria Zanon, Luiz Carlos Carvalho Navegantes, Valéria Ernestânia Chaves, Isis do Carmo Kettelhut

Publikováno v: LipidsREFERENCES. 57(6)

Although it is well established that glucocorticoids inactivate thermogenesis and promote lipid accumulation in interscapular brown adipose tissue (IBAT), the underlying mechanisms remain unknown. We found that dexamethasone treatment (1 mg/kg) for 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c9c263708aabbf2bbe3f466744e285
https://pubmed.ncbi.nlm.nih.gov/36098349

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Interleukin-1 receptor-induced PGE2 production controls acetylcholine-mediated cardiac dysfunction and mortality during scorpion envenomation

Autor: Lenaldo B. Rocha, Camila O S Souza, Alyne F. G. Meirelles, Carlos Arterio Sorgi, Karina F. Zoccal, Mouzarllem B Reis, Natalia Lautherbach, Lúcia Helena Faccioli, Alexandre Kanashiro, Luiz Carlos Carvalho Navegantes, Alessandra Kimie Matsuno, Isis do Carmo Kettelhut, Helio Cesar Salgado, Carlos A. Silva, Palmira Cupo, Fernanda Luciano Rodrigues, Simone G. Ramos, Luiz Gustavo Gardinassi

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Scorpion envenomation is a leading cause of morbidity and mortality among accidents caused by venomous animals. Major clinical manifestations that precede death after scorpion envenomation include heart failure and pulmonary edema. Here, we demonstra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d612771e3e8786a268fc3aeb19f9792
https://doaj.org/article/3824a55bb5ce42fc8ddfb1f913df0a2a

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Calcitonin gene-related peptide exerts inhibitory effects on autophagy in the heart of mice

Autor: Natalia Lautherbach, Henrique Jorge Novaes Morgan, Aline Zanatta Schavinski, Silvia Paula-Gomes, Juliano Machado, Luiz Carlos Carvalho Navegantes, Isis do Carmo Kettelhut

Publikováno v: Peptides 146:170677 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Calcitonin Gene-Related Peptide (CGRP) is a potent vasodilator peptide widely distributed in the central nervous system and various peripheral tissues, including cardiac muscle. However, its role in heart protein metabolism remains unknown. We examin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6682398cfd00e161c172552ae2cb61ff
https://pubmed.ncbi.nlm.nih.gov/34695513

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Insulin/IGF1 signalling mediates the effects of β 2 ‐adrenergic agonist on muscle proteostasis and growth

Autor: Flávia A. Graça, C. Ronald Kahn, Brian T O Neill, Wilian A. Silveira, Diletta Arcidiacono, Luiz Carlos Carvalho Navegantes, Natalia Lautherbach, Leonardo Nogara, Andrea Armani, Marco Sandri, Stefano Realdon, L. H. Manfredi, Dawit A. P. Gonçalves, Isis do Carmo Kettelhut, Enrico Bertaggia, Juliano Machado, Marcelo G. Pereira

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 2, Pp 455-475 (2019)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da UFMG
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG

CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior FAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulo Outra Agência Background: Stimulation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8522d9bd923d25725b2b9f76a5d876
https://doi.org/10.1002/jcsm.12395

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